Gene Expression Literature Summary

• Symbol: Hormad1
• Name: HORMA domain containing 1
• ID: MGI:1915231

19 matching records from 19 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E3.5	E8.5	E12.5	E13.5	E14.5	E15.5	E16.5	E17.5	E18.5	P
Immunohistochemistry (section)					1	1	1	1	1	5
In situ RNA (section)					1					1
Immunohistochemistry (whole mount)								1		3
Northern blot										1
Western blot			1					1		6
RT-PCR	1	2	1	1	2	2		1		8

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Hormad1  HORMA domain containing 1   (Synonyms: 4921522K05Rik, Nohma)
Results	Reference
3*	J:307865 Dahlet T, Truss M, Frede U, Al Adhami H, Bardet AF, Dumas M, Vallet J, Chicher J, Hammann P, Kottnik S, Hansen P, Luz U, Alvarez G, Auclair G, Hecht J, Robinson PN, Hagemeier C, Weber M, E2F6 initiates stable epigenetic silencing of germline genes during embryonic development. Nat Commun. 2021 Jun 11;12(1):3582
1	J:342617 Dali O, D'Cruz S, Legoff L, Diba Lahmidi M, Heitz C, Merret PE, Kernanec PY, Pakdel F, Smagulova F, Transgenerational epigenetic effects imposed by neonicotinoid thiacloprid exposure. Life Sci Alliance. 2024 Feb;7(2)
1	J:173089 Daniel K, Lange J, Hached K, Fu J, Anastassiadis K, Roig I, Cooke HJ, Stewart AF, Wassmann K, Jasin M, Keeney S, Toth A, Meiotic homologue alignment and its quality surveillance are controlled by mouse HORMAD1. Nat Cell Biol. 2011 May;13(5):599-610
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:265597 Gao X, Ma W, Nie J, Zhang C, Zhang J, Yao G, Han J, Xu J, Hu B, Du Y, Shi Q, Yang Z, Huang X, Zhang Y, A G-quadruplex DNA structure resolvase, RHAU, is essential for spermatogonia differentiation. Cell Death Dis. 2015 Jan 22;6:e1610
1*	J:338939 Graham-Paquin AL, Saini D, Sirois J, Hossain I, Katz MS, Zhuang QK, Kwon SY, Yamanaka Y, Bourque G, Bouchard M, Pastor WA, ZMYM2 is essential for methylation of germline genes and active transposons in embryonic development. Nucleic Acids Res. 2023 Aug 11;51(14):7314-7329
2	J:289957 Guan Y, Leu NA, Ma J, Chmatal L, Ruthel G, Bloom JC, Lampson MA, Schimenti JC, Luo M, Wang PJ, SKP1 drives the prophase I to metaphase I transition during male meiosis. Sci Adv. 2020 Mar;6(13):eaaz2129
4	J:325094 Guan Y, Lin H, Leu NA, Ruthel G, Fuchs SY, Busino L, Luo M, Wang PJ, SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination. Nucleic Acids Res. 2022 May 20;50(9):5129-5144
7	J:213984 Kogo H, Tsutsumi M, Ohye T, Inagaki H, Abe T, Kurahashi H, HORMAD1-dependent checkpoint/surveillance mechanism eliminates asynaptic oocytes. Genes Cells. 2012 Jun;17(6):439-54
1	J:301847 Ni L, Xie H, Tan L, Multiple roles of FOXJ3 in spermatogenesis: A lesson from Foxj3 conditional knockout mouse models. Mol Reprod Dev. 2016 Dec;83(12):1060-1069
2	J:325726 Oura S, Hino T, Satoh T, Noda T, Koyano T, Isotani A, Matsuyama M, Akira S, Ishiguro KI, Ikawa M, Trim41 is required to regulate chromosome axis protein dynamics and meiosis in male mice. PLoS Genet. 2022 Jun;18(6):e1010241
1	J:110210 Pangas SA, Choi Y, Ballow DJ, Zhao Y, Westphal H, Matzuk MM, Rajkovic A, Oogenesis requires germ cell-specific transcriptional regulators Sohlh1 and Lhx8. Proc Natl Acad Sci U S A. 2006 May 23;103(21):8090-5
8*	J:94052 Pangas SA, Yan W, Matzuk MM, Rajkovic A, Restricted germ cell expression of a gene encoding a novel mammalian HORMA domain-containing protein. Gene Expr Patterns. 2004 Dec;5(2):257-63
1*	J:256987 Shi B, Xue J, Zhou J, Kasowitz SD, Zhang Y, Liang G, Guan Y, Shi Q, Liu M, Sha J, Huang X, Wang PJ, MORC2B is essential for meiotic progression and fertility. PLoS Genet. 2018 Jan;14(1):e1007175
5*	J:167522 Shin YH, Choi Y, Erdin SU, Yatsenko SA, Kloc M, Yang F, Wang PJ, Meistrich ML, Rajkovic A, Hormad1 mutation disrupts synaptonemal complex formation, recombination, and chromosome segregation in mammalian meiosis. PLoS Genet. 2010;6(11):e1001190
1	J:322322 Tanno N, Takemoto K, Takada-Horisawa Y, Shimada R, Fujimura S, Tani N, Takeda N, Araki K, Ishiguro KI, FBXO47 is essential for preventing the synaptonemal complex from premature disassembly in mouse male meiosis. iScience. 2022 Apr 15;25(4):104008
1	J:263202 Ungewitter EK, Rotgers E, Kang HS, Lichti-Kaiser K, Li L, Grimm SA, Jetten AM, Yao HH, Loss of Glis3 causes dysregulation of retrotransposon silencing and germ cell demise in fetal mouse testis. Sci Rep. 2018 Jun 25;8(1):9662
1	J:281207 Vazquez BN, Blengini CS, Hernandez Y, Serrano L, Schindler K, SIRT7 promotes chromosome synapsis during prophase I of female meiosis. Chromosoma. 2019 Sep;128(3):369-383
1	J:268520 Zhang Q, Shao J, Fan HY, Yu C, Evolutionarily-conserved MZIP2 is essential for crossover formation in mammalian meiosis. Commun Biol. 2018;1:147