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Gene Expression Literature Summary
Symbol
Name
ID
Fzd2
frizzled class receptor 2
MGI:1888513

48 matching records from 48 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E0.5 E1 E1.5 E2 E3 E3.5 E4 E5.5 E6.5 E7.5 E8 E8.5 E9.5 E10 E10.5 E11 E11.5 E12 E12.5 E13 E13.5 E14 E14.5 E15 E15.5 E16 E16.5 E17 E17.5 E18 E18.5 E P
Immunohistochemistry (section) 1 1 1
In situ RNA (section) 2 1 1 1 2 6 1 2 8 1 2 2 2 2 1 4
In situ RNA (whole mount) 1 1 1 1 1
In situ reporter (knock in) 1 1 1 1 1
Northern blot 1 1 1 1 1
RT-PCR 1 1 2 2 1 1 1 1 1 1 2 1 3 2 1 10 1 1 2 10 2 1 1 1 1 1 2 1 12
cDNA clones 1 1 2 1 1
RNase protection 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Fzd2  frizzled class receptor 2   (Synonyms: Fz10, Mfz10, Mfz10a)
Results  Reference
3J:169706 Abdul-Ghani M, Dufort D, Stiles R, De Repentigny Y, Kothary R, Megeney LA, Wnt11 promotes cardiomyocyte development by caspase-mediated suppression of canonical Wnt signals. Mol Cell Biol. 2011 Jan;31(1):163-78
1J:155074 Agalliu D, Takada S, Agalliu I, McMahon AP, Jessell TM, Motor neurons with axial muscle projections specified by Wnt4/5 signaling. Neuron. 2009 Mar 12;61(5):708-20
1J:156721 Alfieri CM, Cheek J, Chakraborty S, Yutzey KE, Wnt signaling in heart valve development and osteogenic gene induction. Dev Biol. 2010 Feb 15;338(2):127-35
1J:236211 Aviles EC, Pinto C, Hanna P, Ojeda J, Perez V, De Ferrari GV, Zamorano P, Albistur M, Sandoval D, Henriquez JP, Frizzled-9 impairs acetylcholine receptor clustering in skeletal muscle cells. Front Cell Neurosci. 2014;8:110
5J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303
5*J:93300 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL, Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
1J:160559 Caronia G, Wilcoxon J, Feldman P, Grove EA, Bone morphogenetic protein signaling in the developing telencephalon controls formation of the hippocampal dentate gyrus and modifies fear-related behavior. J Neurosci. 2010 May 5;30(18):6291-301
2J:98338 Chu EY, Hens J, Andl T, Kairo A, Yamaguchi TP, Brisken C, Glick A, Wysolmerski JJ, Millar SE, Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis. Development. 2004 Oct;131(19):4819-29
1J:161416 Collette NM, Genetos DC, Murugesh D, Harland RM, Loots GG, Genetic evidence that SOST inhibits WNT signaling in the limb. Dev Biol. 2010 Jun 15;342(2):169-79
5J:148823 Corrigan PM, Dobbin E, Freeburn RW, Wheadon H, Patterns of Wnt/Fzd/LRP gene expression during embryonic hematopoiesis. Stem Cells Dev. 2009 Jun;18(5):759-72
1J:167834 Dawe CE, Kooistra MK, Fairbridge NA, Pisio AC, McDermid HE, Role of chromatin remodeling gene Cecr2 in neurulation and inner ear development. Dev Dyn. 2011 Feb;240(2):372-83
1J:95872 De Langhe SP, Sala FG, Del Moral PM, Fairbanks TJ, Yamada KM, Warburton D, Burns RC, Bellusci S, Dickkopf-1 (DKK1) reveals that fibronectin is a major target of Wnt signaling in branching morphogenesis of the mouse embryonic lung. Dev Biol. 2005 Jan 15;277(2):316-31
4J:122979 Deutscher E, Hung-Chang Yao H, Essential roles of mesenchyme-derived beta-catenin in mouse Mullerian duct morphogenesis. Dev Biol. 2007 Jul 15;307(2):227-36
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
6J:72420 Douglas KR, Brinkmeier ML, Kennell JA, Eswara P, Harrison TA, Patrianakos AI, Sprecher BS, Potok MA, Lyons RH Jr, MacDougald OA, Camper SA, Identification of members of the Wnt signaling pathway in the embryonic pituitary gland. Mamm Genome. 2001 Nov;12(11):843-51
3J:124170 Fischer T, Guimera J, Wurst W, Prakash N, Distinct but redundant expression of the Frizzled Wnt receptor genes at signaling centers of the developing mouse brain. Neuroscience. 2007 Jul 13;147(3):693-711
1J:167570 Funato Y, Terabayashi T, Sakamoto R, Okuzaki D, Ichise H, Nojima H, Yoshida N, Miki H, Nucleoredoxin sustains Wnt/beta-catenin signaling by retaining a pool of inactive dishevelled protein. Curr Biol. 2010 Nov 9;20(21):1945-52
3J:202907 Grigoryan T, Stein S, Qi J, Wende H, Garratt AN, Nave KA, Birchmeier C, Birchmeier W, Wnt/Rspondin/beta-catenin signals control axonal sorting and lineage progression in Schwann cell development. Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18174-9
2*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. http://www.gudmap.org. 2004;
7*J:122362 Harwood BN, Cross SK, Radford EE, Haac BE, de Vries WN, Members of the WNT signaling pathways are widely expressed in mouse ovaries, oocytes, and cleavage stage embryos. Dev Dyn. 2008;237(4):1099-1111
9J:80135 Heller RS, Dichmann DS, Jensen J, Miller C, Wong G, Madsen OD, Serup P, Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation. Dev Dyn. 2002 Nov;225(3):260-70
1J:232894 Hrycaj SM, Dye BR, Baker NC, Larsen BM, Burke AC, Spence JR, Wellik DM, Hox5 Genes Regulate the Wnt2/2b-Bmp4-Signaling Axis during Lung Development. Cell Rep. 2015 Aug 11;12(6):903-12
2J:213915 Kadzik RS, Cohen ED, Morley MP, Stewart KM, Lu MM, Morrisey EE, Wnt ligand/Frizzled 2 receptor signaling regulates tube shape and branch-point formation in the lung through control of epithelial cell shape. Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):12444-9
1J:234970 Kalyani R, Lee JY, Min H, Yoon H, Kim MH, Genes Frequently Coexpressed with Hoxc8 Provide Insight into the Discovery of Target Genes. Mol Cells. 2016 May 31;39(5):395-402
5*J:122405 Kemp CR, Willems E, Wawrzak D, Hendrickx M, Agbor Agbor T, Leyns L, Expression of Frizzled5, Frizzled7, and Frizzled10 during early mouse development and interactions with canonical Wnt signaling. Dev Dyn. 2007 Jul;236(7):2011-9
1J:239290 Knosp WM, Knox SM, Lombaert IM, Haddox CL, Patel VN, Hoffman MP, Submandibular parasympathetic gangliogenesis requires sprouty-dependent Wnt signals from epithelial progenitors. Dev Cell. 2015 Mar 23;32(6):667-77
2J:239872 Larsen BM, Hrycaj SM, Newman M, Li Y, Wellik DM, Mesenchymal Hox6 function is required for mouse pancreatic endocrine cell differentiation. Development. 2015 Nov 15;142(22):3859-68
3*J:139251 Lin C, Yin Y, Long F, Ma L, Tissue-specific requirements of beta-catenin in external genitalia development. Development. 2008 Aug;135(16):2815-25
9J:63899 Malik TH, Shivdasani RA, Structure and expression of a novel frizzled gene isolated from the developing mouse gut. Biochem J. 2000 Aug 1;349 Pt 3:829-34
1J:154534 Martinez G, Wijesinghe M, Turner K, Abud HE, Taketo MM, Noda T, Robinson ML, de Iongh RU, Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation. Invest Ophthalmol Vis Sci. 2009 Oct;50(10):4794-806
3J:132979 Potok MA, Cha KB, Hunt A, Brinkmeier ML, Leitges M, Kispert A, Camper SA, WNT signaling affects gene expression in the ventral diencephalon and pituitary gland growth. Dev Dyn. 2008 Apr;237(4):1006-20
4J:91248 Reddy ST, Andl T, Lu MM, Morrisey EE, Millar SE, Expression of frizzled genes in developing and postnatal hair follicles. J Invest Dermatol. 2004 Aug;123(2):275-82
1*J:149737 Sansom SN, Griffiths DS, Faedo A, Kleinjan DJ, Ruan Y, Smith J, van Heyningen V, Rubenstein JL, Livesey FJ, The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. PLoS Genet. 2009 Jun;5(6):e1000511
2*J:152946 Sferruzzi-Perri AN, Macpherson AM, Roberts CT, Robertson SA, Csf2 null mutation alters placental gene expression and trophoblast glycogen cell and giant cell abundance in mice. Biol Reprod. 2009 Jul;81(1):207-21
1J:173385 Stefater JA 3rd, Lewkowich I, Rao S, Mariggi G, Carpenter AC, Burr AR, Fan J, Ajima R, Molkentin JD, Williams BO, Wills-Karp M, Pollard JW, Yamaguchi T, Ferrara N, Gerhardt H, Lang RA, Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells. Nature. 2011 Jun 23;474(7352):511-5
1J:84052 Stump RJ, Ang S, Chen Y, von Bahr T, Lovicu FJ, Pinson K, de Iongh RU, Yamaguchi TP, Sassoon DA, McAvoy JW, A role for Wnt/beta-catenin signaling in lens epithelial differentiation. Dev Biol. 2003 Jul 1;259(1):48-61
1*J:133947 Summerhurst K, Stark M, Sharpe J, Davidson D, Murphy P, 3D representation of Wnt and Frizzled gene expression patterns in the mouse embryo at embryonic day 11.5 (Ts19). Gene Expr Patterns. 2008 May;8(5):331-48
2J:236406 Takada Y, Fukuda A, Chiba T, Seno H, Brg1 plays an essential role in development and homeostasis of the duodenum through regulation of Notch signaling. Development. 2016 Oct 1;143(19):3532-3539
2*J:174767 Tang F, Barbacioru C, Nordman E, Bao S, Lee C, Wang X, Tuch BB, Heard E, Lao K, Surani MA, Deterministic and stochastic allele specific gene expression in single mouse blastomeres. PLoS One. 2011;6(6):e21208
5J:74122 van Gijn ME, Blankesteijn WM, Smits JF, Hierck B, Gittenberger-de Groot AC, Frizzled 2 is transiently expressed in neural crest-containing areas during development of the heart and great arteries in the mouse. Anat Embryol (Berl). 2001 Mar;203(3):185-92
1*J:118503 Verani R, Cappuccio I, Spinsanti P, Gradini R, Caruso A, Magnotti MC, Motolese M, Nicoletti F, Melchiorri D, Expression of the Wnt inhibitor Dickkopf-1 is required for the induction of neural markers in mouse embryonic stem cells differentiating in response to retinoic acid. J Neurochem. 2007 Jan;100(1):242-50
2*J:127119 Visel A, Carson J, Oldekamp J, Warnecke M, Jakubcakova V, Zhou X, Shaw CA, Alvarez-Bolado G, Eichele G, Regulatory pathway analysis by high-throughput in situ hybridization. PLoS Genet. 2007 Oct 19;3(10):1867-83
1*J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
7J:37068 Wang Y, Macke JP, Abella BS, Andreasson K, Worley P, Gilbert DJ, Copeland NG, Jenkins NA, Nathans J, A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled. J Biol Chem. 1996 Feb 23;271(8):4468-76
1J:144660 Yoshida Y, Han B, Mendelsohn M, Jessell TM, PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord. Neuron. 2006 Dec 7;52(5):775-88
3J:165556 Yu H, Smallwood PM, Wang Y, Vidaltamayo R, Reed R, Nathans J, Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes. Development. 2010 Nov;137(21):3707-17
2*J:189062 Yu H, Ye X, Guo N, Nathans J, Frizzled 2 and frizzled 7 function redundantly in convergent extension and closure of the ventricular septum and palate: evidence for a network of interacting genes. Development. 2012 Dec;139(23):4383-94
3J:138407 Zhang Y, Goss AM, Cohen ED, Kadzik R, Lepore JJ, Muthukumaraswamy K, Yang J, DeMayo FJ, Whitsett JA, Parmacek MS, Morrisey EE, A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration. Nat Genet. 2008 Jul;40(7):862-70

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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory