Gene Expression Literature Summary

• Symbol: Cxcl13
• Name: C-X-C motif chemokine ligand 13
• ID: MGI:1888499

22 matching records from 22 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E11.5	E12.5	E13.5	E14.5	E15.5	E16.5	E17.5	E18.5	P
Immunohistochemistry (section)		1	2	2			2	2	5
In situ RNA (section)	1	1		1	2			1	3
In situ RNA (whole mount)					1		1
RT-PCR						1	2		6

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Cxcl13  C-X-C motif chemokine ligand 13   (Synonyms: 4631412M08Rik, ANGIE2, BCA-1, BLC, Scyb13)
Results	Reference
2	J:71805 Bleul CC, Boehm T, Chemokines define distinct microenvironments in the developing thymus. Eur J Immunol. 2000 Dec;30(12):3371-9
1	J:196959 Castagnaro L, Lenti E, Maruzzelli S, Spinardi L, Migliori E, Farinello D, Sitia G, Harrelson Z, Evans SM, Guidotti LG, Harvey RP, Brendolan A, Nkx2-5(+)islet1(+) mesenchymal precursors generate distinct spleen stromal cell subsets and participate in restoring stromal network integrity. Immunity. 2013 Apr 18;38(4):782-91
1	J:337474 Cobo I, Paliwal S, Bodas C, Felipe I, Melia-Aloma J, Torres A, Martinez-Villarreal J, Malumbres M, Garcia F, Millan I, Del Pozo N, Park JC, MacDonald RJ, Munoz J, Mendez R, Real FX, NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and restrains PDAC initiation. Nat Commun. 2023 Jun 23;14(1):3761
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:82631 Fukuda K, Yoshida H, Sato T, Furumoto TA, Mizutani-Koseki Y, Suzuki Y, Saito Y, Takemori T, Kimura M, Sato H, Taniguchi M, Nishikawa S, Nakayama T, Koseki H, Mesenchymal expression of Foxl1, a winged helix transcriptional factor, regulates generation and maintenance of gut-associated lymphoid organs. Dev Biol. 2003 Mar 15;255(2):278-89
1	J:139331 Fukuyama S, Nagatake T, Kim DY, Takamura K, Park EJ, Kaisho T, Tanaka N, Kurono Y, Kiyono H, Cutting edge: Uniqueness of lymphoid chemokine requirement for the initiation and maturation of nasopharynx-associated lymphoid tissue organogenesis. J Immunol. 2006 Oct 1;177(7):4276-80
1	J:310429 Furtado GC, Pacer ME, Bongers G, Benezech C, He Z, Chen L, Berin MC, Kollias G, Caamano JH, Lira SA, TNFalpha-dependent development of lymphoid tissue in the absence of RORgammat+ lymphoid tissue inducer cells. Mucosal Immunol. 2014;7(3):602-14
2*	J:67917 Honda K, Nakano H, Yoshida H, Nishikawa S, Rennert P, Ikuta K, Tamechika M, Yamaguchi K, Fukumoto T, Chiba T, Nishikawa SI, Molecular basis for hematopoietic/mesenchymal interaction during initiation of peyer's patch organogenesis. J Exp Med. 2001 Mar 5;193(5):621-30
1	J:277787 Ikuta K, Fukuda A, Ogawa S, Masuo K, Goto N, Hiramatsu Y, Tsuda M, Kimura Y, Matsumoto Y, Kimura Y, Maruno T, Kanda K, Nishi K, Takaori K, Uemoto S, Takaishi S, Chiba T, Nishi E, Seno H, Nardilysin inhibits pancreatitis and suppresses pancreatic ductal adenocarcinoma initiation in mice. Gut. 2019 May;68(5):882-892
2	J:324834 Lenti E, Genovese L, Bianchessi S, Maurizio A, Sain SB, di Lillo A, Mattavelli G, Harel I, Bernassola F, Hehlgans T, Pfeffer K, Crosti M, Abrignani S, Evans SM, Sitia G, Guimaraes-Camboa N, Russo V, van de Pavert SA, Garcia-Manteiga JM, Brendolan A, Fate mapping and scRNA sequencing reveal origin and diversity of lymph node stromal precursors. Immunity. 2022 Apr 12;55(4):606-622.e6
1*	J:293091 Li Z, Li Y, Jiao J, Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
4	J:320730 Neely HR, Flajnik MF, CXCL13 responsiveness but not CXCR5 expression by late transitional B cells initiates splenic white pulp formation. J Immunol. 2015 Mar 15;194(6):2616-23
2	J:217542 Obata Y, Kimura S, Nakato G, Iizuka K, Miyagawa Y, Nakamura Y, Furusawa Y, Sugiyama M, Suzuki K, Ebisawa M, Fujimura Y, Yoshida H, Iwanaga T, Hase K, Ohno H, Epithelial-stromal interaction via Notch signaling is essential for the full maturation of gut-associated lymphoid tissues. EMBO Rep. 2014 Dec;15(12):1297-304
1	J:259045 Onder L, Morbe U, Pikor N, Novkovic M, Cheng HW, Hehlgans T, Pfeffer K, Becher B, Waisman A, Rulicke T, Gommerman J, Mueller CG, Sawa S, Scandella E, Ludewig B, Lymphatic Endothelial Cells Control Initiation of Lymph Node Organogenesis. Immunity. 2017 Jul 18;47(1):80-92.e4
1	J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22
1	J:112368 Sato T, Endoh M, Yoshida H, Yasuo S, Katsuno T, Saito Y, Isono K, Koseki H, Mammalian Polycomb complexes are required for Peyer's patch development by regulating lymphoid cell proliferation. Gene. 2006 Sep 1;379:166-74
1*	J:262410 Tanabe S, Yamashita T, B-1a lymphocytes promote oligodendrogenesis during brain development. Nat Neurosci. 2018 Apr;21(4):506-516
3	J:336858 Vallecillo-Garcia P, Orgeur M, Comai G, Poehle-Kronnawitter S, Fischer C, Gloger M, Dumas CE, Giesecke-Thiel C, Sauer S, Tajbakhsh S, Hopken UE, Stricker S, A local subset of mesenchymal cells expressing the transcription factor Osr1 orchestrates lymph node initiation. Immunity. 2023 Jun 13;56(6):1204-1219.e8
2	J:157747 van de Pavert SA, Olivier BJ, Goverse G, Vondenhoff MF, Greuter M, Beke P, Kusser K, Hopken UE, Lipp M, Niederreither K, Blomhoff R, Sitnik K, Agace WW, Randall TD, de Jonge WJ, Mebius RE, Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation. Nat Immunol. 2009 Nov;10(11):1193-9
1*	J:64739 Wada R, Tifft CJ, Proia RL, Microglial activation precedes acute neurodegeneration in sandhoff disease and is suppressed by bone marrow transplantation. Proc Natl Acad Sci U S A. 2000 Sep 26;97(20):10954-9
1	J:64018 Wang CC, Biben C, Robb L, Nassir F, Barnett L, Davidson NO, Koentgen F, Tarlinton D, Harvey RP, Homeodomain factor Nkx2-3 controls regional expression of leukocyte homing coreceptor MAdCAM-1 in specialized endothelial cells of the viscera. Dev Biol. 2000 Aug 15;224(2):152-67