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Gene Expression Literature Summary
Symbol
Name
ID
Pdgfc
platelet-derived growth factor, C polypeptide
MGI:1859631

23 matching records from 23 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E1.5 E2 E9.5 E10.5 E11 E11.5 E12 E12.5 E13 E13.5 E14.5 E15 E15.5 E16.5 E17 E18.5 E19 E A
In situ protein (section) 1 1 1 2 1 1 1
In situ RNA (section) 1 1 2 1 4 4 1 3 1 1 1 1
In situ RNA (whole mount) 2 1 2 1 2 2
In situ reporter (knock in) 1
Northern blot 2 2
Western blot 1 1 1 1 1 1 2
RT-PCR 1 1 1 1
cDNA clones 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Pdgfc  platelet-derived growth factor, C polypeptide   (Synonyms: 1110064L01Rik, PDGF-C)
Results  Reference
10*J:73808 Aase K, Abramsson A, Karlsson L, Betsholtz C, Eriksson U, Expression analysis of PDGF-C in adult and developing mouse tissues. Mech Dev. 2002 Jan;110(1-2):187-91
1J:205009 Andrae J, Ehrencrona H, Gallini R, Lal M, Ding H, Betsholtz C, Analysis of mice lacking the heparin-binding splice isoform of platelet-derived growth factor A. Mol Cell Biol. 2013 Oct;33(20):4030-40
6J:196196 Awuah PK, Nejak-Bowen KN, Monga SP, Role and Regulation of PDGFRalpha Signaling in Liver Development and Regeneration. Am J Pathol. 2013 May;182(5):1648-58
2J:82564 Brennan J, Tilmann C, Capel B, Pdgfr-alpha mediates testis cord organization and fetal Leydig cell development in the XY gonad. Genes Dev. 2003 Mar 15;17(6):800-10
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
3J:93954 Ding H, Wu X, Bostrom H, Kim I, Wong N, Tsoi B, O'Rourke M, Koh GY, Soriano P, Betsholtz C, Hart TC, Marazita ML, Field LL, Tam PP, Nagy A, A specific requirement for PDGF-C in palate formation and PDGFR-alpha signaling. Nat Genet. 2004 Oct;36(10):1111-6
9J:64341 Ding H, Wu X, Kim I, Tam PP, Koh GY, Nagy A, The mouse pdgfc gene: dynamic expression in embryonic tissues during organogenesis. Mech Dev. 2000 Sep;96(2):209-13
1J:93392 Fredriksson L, Li H, Fieber C, Li X, Eriksson U, Tissue plasminogen activator is a potent activator of PDGF-CC. EMBO J. 2004 Sep 29;23(19):3793-802
1*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. http://www.gudmap.org. 2004;
1*J:166721 He F, Popkie AP, Xiong W, Li L, Wang Y, Phiel CJ, Chen Y, Gsk3beta is required in the epithelium for palatal elevation in mice. Dev Dyn. 2010 Dec;239(12):3235-46
2J:202450 He F, Soriano P, A Critical Role for PDGFRalpha Signaling in Medial Nasal Process Development. PLoS Genet. 2013 Sep;9(9):e1003851
4J:135147 Kurahashi M, Niwa Y, Cheng J, Ohsaki Y, Fujita A, Goto H, Fujimoto T, Torihashi S, Platelet-derived growth factor signals play critical roles in differentiation of longitudinal smooth muscle cells in mouse embryonic gut. Neurogastroenterol Motil. 2008 May;20(5):521-31
1J:62052 Li X, Ponten A, Aase K, Karlsson L, Abramsson A, Uutela M, Backstrom G, Hellstrom M, Bostrom H, Li H, Soriano P, Betsholtz C, Heldin CH, Alitalo K, Ostman A, Eriksson U, PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor [see comments]. Nat Cell Biol. 2000 May;2(5):302-9
1*J:171624 Machold R, Klein C, Fishell G, Genes expressed in Atoh1 neuronal lineages arising from the r1/isthmus rhombic lip. Gene Expr Patterns. 2011 Jun-Jul;11(5-6):349-59
1J:185583 Metzakopian E, Lin W, Salmon-Divon M, Dvinge H, Andersson E, Ericson J, Perlmann T, Whitsett JA, Bertone P, Ang SL, Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors. Development. 2012 Jul;139(14):2625-34
1J:165035 Niklasson M, Bergstrom T, Zhang XQ, Gustafsdottir SM, Sjogren M, Edqvist PH, Vennstrom B, Forsberg M, Forsberg-Nilsson K, Enlarged lateral ventricles and aberrant behavior in mice overexpressing PDGF-B in embryonic neural stem cells. Exp Cell Res. 2010 Oct 15;316(17):2779-89
4J:146617 Olson LE , Soriano P, Increased PDGFRalpha activation disrupts connective tissue development and drives systemic fibrosis. Dev Cell. 2009 Feb;16(2):303-13
2*J:174767 Tang F, Barbacioru C, Nordman E, Bao S, Lee C, Wang X, Tuch BB, Heard E, Lao K, Surani MA, Deterministic and stochastic allele specific gene expression in single mouse blastomeres. PLoS One. 2011;6(6):e21208
1J:134482 Teng L, Mundell NA, Frist AY, Wang Q, Labosky PA, Requirement for Foxd3 in the maintenance of neural crest progenitors. Development. 2008 May;135(9):1615-24
1J:184925 Wang Y, Serra R, PDGF mediates TGFbeta-induced migration during development of the spinous process. Dev Biol. 2012 May 1;365(1):110-7
2J:205063 Wiradjaja F, Cottle DL, Jones L, Smyth I, Regulation of PDGFC signalling and extracellular matrix composition by FREM1 in mice. Dis Model Mech. 2013 Nov;6(6):1426-33
1J:128709 Wu X, Ding H, Generation of conditional knockout alleles for PDGF-C. Genesis. 2007 Oct;45(10):653-7
2J:114601 Zhuo Y, Hoyle GW, Shan B, Levy DR, Lasky JA, Over-expression of PDGF-C using a lung specific promoter results in abnormal lung development. Transgenic Res. 2006 Oct;15(5):543-55

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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory