Gene Expression Literature Summary

• Symbol: Eif2ak4
• Name: eukaryotic translation initiation factor 2 alpha kinase 4
• ID: MGI:1353427

8 matching records from 8 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E9.5	E12.5	E13.5	E15.5	E17.5	E18.5	P
Immunohistochemistry (section)		1		1
Western blot	1		2		1	1	3
RT-PCR						1	1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Eif2ak4  eukaryotic translation initiation factor 2 alpha kinase 4   (Synonyms: GCN2)
Results	Reference
2*	J:143177 Alves VS, Motta FL, Roffe M, Delamano A, Pesquero JB, Castilho BA, GCN2 activation and eIF2alpha phosphorylation in the maturation of mouse oocytes. Biochem Biophys Res Commun. 2009 Jan 2;378(1):41-4
1	J:129752 Elefteriou F, Benson MD, Sowa H, Starbuck M, Liu X, Ron D, Parada LF, Karsenty G, ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae. Cell Metab. 2006 Dec;4(6):441-51
1*	J:241343 Furuya S, Yoshida K, Kawakami Y, Yang JH, Sayano T, Azuma N, Tanaka H, Kuhara S, Hirabayashi Y, Inactivation of the 3-phosphoglycerate dehydrogenase gene in mice: changes in gene expression and associated regulatory networks resulting from serine deficiency. Funct Integr Genomics. 2008 Aug;8(3):235-49
1	J:305864 Kalish BT, Kim E, Finander B, Duffy EE, Kim H, Gilman CK, Yim YS, Tong L, Kaufman RJ, Griffith EC, Choi GB, Greenberg ME, Huh JR, Maternal immune activation in mice disrupts proteostasis in the fetal brain. Nat Neurosci. 2021 Feb;24(2):204-213
4	J:216392 Kraushar ML, Thompson K, Wijeratne HR, Viljetic B, Sakers K, Marson JW, Kontoyiannis DL, Buyske S, Hart RP, Rasin MR, Temporally defined neocortical translation and polysome assembly are determined by the RNA-binding protein Hu antigen R. Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):E3815-24
1	J:253948 Magarin M, Pohl T, Lill A, Schulz H, Blaschke F, Heuser A, Thierfelder L, Donath S, Drenckhahn JD, Embryonic cardiomyocytes can orchestrate various cell protective mechanisms to survive mitochondrial stress. J Mol Cell Cardiol. 2016 Aug;97:1-14
1	J:282947 Poncet N, Halley PA, Lipina C, Gierlinski M, Dady A, Singer GA, Febrer M, Shi YB, Yamaguchi TP, Taylor PM, Storey KG, Wnt regulates amino acid transporter Slc7a5 and so constrains the integrated stress response in mouse embryos. EMBO Rep. 2020 Jan 7;21(1):e48469
1*	J:287528 Yamazaki H, Kasai S, Mimura J, Ye P, Inose-Maruyama A, Tanji K, Wakabayashi K, Mizuno S, Sugiyama F, Takahashi S, Sato T, Ozaki T, Cavener DR, Yamamoto M, Itoh K, Ribosome binding protein GCN1 regulates the cell cycle and cell proliferation and is essential for the embryonic development of mice. PLoS Genet. 2020 Apr;16(4):e1008693