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Gene Expression Literature Summary
Symbol
Name
ID
Esr1
estrogen receptor 1 (alpha)
MGI:1352467

54 matching records from 54 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E1 E1.5 E2 E2.5 E3 E3.5 E4 E4.5 E5.5 E6.5 E7 E7.5 E8.5 E9.5 E10.5 E11 E11.5 E12.5 E13 E13.5 E14 E14.5 E15 E15.5 E16 E16.5 E17 E17.5 E18 E18.5 E19 E19.5 E20 E A
In situ protein (section) 1 1 1 1 2 1 2 2 6 1 4 7 5 8 1 2 1 1 1 18
In situ RNA (section) 1 2 1 1 1 2 2 2 2 1 1 1 6
In situ RNA (whole mount) 1 1
Western blot 1 1 1 1 1 1 1
RT-PCR 1 1 3 2 2 3 2 1 1 1 1 2 1 1 4 3 2 1 3 2 3 1 4 11
RNase protection 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Esr1  estrogen receptor 1 (alpha)   (Synonyms: ERa, ER[a], ERalpha, ER-alpha, ESR, Estr, Estra, Nr3a1)
Results  Reference
1J:201201 Anthwal N, Pelling M, Claxton S, Mellitzer G, Collin C, Kessaris N, Richardson WD, Gradwohl G, Ang SL, Conditional deletion of neurogenin-3 using Nkx2.1iCre results in a mouse model for the central control of feeding, activity and obesity. Dis Model Mech. 2013 Sep-Oct;6(5):1133-45
1J:185713 Asselin-Labat ML, Sutherland KD, Barker H, Thomas R, Shackleton M, Forrest NC, Hartley L, Robb L, Grosveld FG, van der Wees J, Lindeman GJ, Visvader JE, Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation. Nat Cell Biol. 2007 Feb;9(2):201-9
5J:141806 Barle EL, Pogacnik A, Zabavnik J, Expression of oestrogen receptor alpha during development of the skeleton in mice fetuses: immunohistochemical study. Anat Histol Embryol. 2008 Dec;37(6):408-14
5*J:85725 Beyer C, Kuppers E, Karolczak M, Trotter A, Ontogenetic expression of estrogen and progesterone receptors in the mouse lung. Biol Neonate. 2003;84(1):59-63
3*J:93300 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL, Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
3*J:42031 Bonnelye E, Vanacker JM, Spruyt N, Alric S, Fournier B, Desbiens X , Laudet V, Expression of the estrogen-related receptor 1 (ERR-1) orphan receptor during mouse development. Mech Dev. 1997 Jul;65(1-2):71-85
1J:129948 Cederroth CR, Schaad O, Descombes P, Chambon P, Vassalli JD, Nef S, Estrogen receptor alpha is a major contributor to estrogen-mediated fetal testis dysgenesis and cryptorchidism. Endocrinology. 2007 Nov;148(11):5507-19
2J:195350 Chaen T, Konno T, Egashira M, Bai R, Nomura N, Nomura S, Hirota Y, Sakurai T, Imakawa K, Estrogen-dependent uterine secretion of osteopontin activates blastocyst adhesion competence. PLoS One. 2012;7(11):e48933
4J:119560 Choi MY, Romer AI, Hu M, Lepourcelet M, Mechoor A, Yesilaltay A, Krieger M, Gray PA, Shivdasani RA, A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development. Development. 2006 Oct;133(20):4119-29
2*J:168654 Chung YC, Tsai YJ, Shiu TY, Sun YY, Wang PF, Chen CL, Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):84-92
1J:178944 Daikoku T, Cha J, Sun X, Tranguch S, Xie H, Fujita T, Hirota Y, Lydon J, Demayo F, Maxson R, Dey SK, Conditional Deletion of MSX Homeobox Genes in the Uterus Inhibits Blastocyst Implantation by Altering Uterine Receptivity. Dev Cell. 2011 Dec 13;21(6):1014-25
5J:39341 Das N, Wang J, Dey SK, Uterine preparation for implantation in the mouse is associated with coordinate expression of estrogen-responsive finger protein and estrogen receptor. Mol Reprod Dev. 1997 Apr;46(4):499-506
1J:77469 Davis AM, Henion TR, Tobet SA, Gamma-aminobutyric acidB receptors and the development of the ventromedial nucleus of the hypothalamus. J Comp Neurol. 2002 Jul 29;449(3):270-80
3J:87441 Davis AM, Seney ML, Walker HJ, Tobet SA, Differential colocalization of Islet-1 and estrogen receptor alpha in the murine preoptic area and hypothalamus during development. Endocrinology. 2004 Jan;145(1):360-6
1J:79217 Dellovade TL, Davis AM, Ferguson C, Sieghart W, Homanics GE, Tobet SA, GABA influences the development of the ventromedial nucleus of the hypothalamus. J Neurobiol. 2001 Dec;49(4):264-76
3J:63148 Dellovade TL, Young M, Ross EP, Henderson R, Caron K, Parker K, Tobet SA, Disruption of the gene encoding SF-1 alters the distribution of hypothalamic neuronal phenotypes. J Comp Neurol. 2000 Aug 7;423(4):579-89
1J:108241 Desai J, Shannon ME, Johnson MD, Ruff DW, Hughes LA, Kerley MK, Carpenter DA, Johnson DK, Rinchik EM, Culiat CT, Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects. Hum Mol Genet. 2006 Apr 15;15(8):1329-41
2J:206605 Faisal M, Kim H, Kim J, Sexual differences of imprinted genes' expression levels. Gene. 2014 Jan 1;533(1):434-8
3J:124101 Fan X, Kim HJ, Warner M, Gustafsson JA, Estrogen receptor beta is essential for sprouting of nociceptive primary afferents and for morphogenesis and maintenance of the dorsal horn interneurons. Proc Natl Acad Sci U S A. 2007 Aug 21;104(34):13696-701
1J:192165 Forsman CL, Ng BC, Heinze RK, Kuo C, Sergi C, Gopalakrishnan R, Yee D, Graf D, Schwertfeger KL, Petryk A, BMP-binding protein twisted gastrulation is required in mammary gland epithelium for normal ductal elongation and myoepithelial compartmentalization. Dev Biol. 2013 Jan 1;373(1):95-106
3*J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
3*J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
7J:41465 Greco TL, Furlow JD, Duello TM, Gorski J, Immunodetection of estrogen receptors in fetal and neonatal female mouse reproductive tracts. Endocrinology. 1991 Sep;129(3):1326-32
1J:121940 Grimm SL, Bu W, Longley MA, Roop DR, Li Y, Rosen JM, Keratin 6 is not essential for mammary gland development. Breast Cancer Res. 2006;8(3):R29
1J:163218 Gu B, Sun P, Yuan Y, Moraes RC, Li A, Teng A, Agrawal A, Rheaume C, Bilanchone V, Veltmaat JM, Takemaru K, Millar S, Lee EY, Lewis MT, Li B, Dai X, Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation. J Cell Biol. 2009 Jun 1;185(5):811-26
4*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. http://www.gudmap.org. 2004;
7*J:140465 Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND, Robson P, Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Dev Cell. 2010 Apr 20;18(4):675-85
1J:124667 Heckman BM, Chakravarty G, Vargo-Gogola T, Gonzales-Rimbau M, Hadsell DL, Lee AV, Settleman J, Rosen JM, Crosstalk between the p190-B RhoGAP and IGF signaling pathways is required for embryonic mammary bud development. Dev Biol. 2007 Sep 1;309(1):137-49
3J:60105 Henderson RG, Brown AE, Tobet SA, Sex differences in cell migration in the preoptic area/anterior hypothalamus of mice. J Neurobiol. 1999 Nov 5;41(2):252-66
3J:189075 Hiremath M, Dann P, Fischer J, Butterworth D, Boras-Granic K, Hens J, Van Houten J, Shi W, Wysolmerski J, Parathyroid hormone-related protein activates Wnt signaling to specify the embryonic mammary mesenchyme. Development. 2012 Nov;139(22):4239-49
5*J:54776 Hiroi H, Momoeda M, Inoue S, Tsuchiya F, Matsumi H, Tsutsumi O, Muramatsu M, Taketani Y, Stage-specific expression of estrogen receptor subtypes and estrogen responsive finger protein in preimplantational mouse embryos. Endocr J. 1999 Feb;46(1):153-8
3J:138181 Ikeda Y, Tanaka H, Esaki M, Effects of gestational diethylstilbestrol treatment on male and female gonads during early embryonic development. Endocrinology. 2008 Aug;149(8):3970-9
2*J:63372 Ivanova T, Beyer C, Ontogenetic expression and sex differences of aromatase and estrogen receptor-alpha/beta mRNA in the mouse hippocampus. Cell Tissue Res. 2000 May;300(2):231-7
2J:59952 Jefferson WN, Couse JF, Banks EP, Korach KS, Newbold RR, Expression of estrogen receptor beta is developmentally regulated in reproductive tissues of male and female mice. Biol Reprod. 2000 Feb;62(2):310-7
2J:207602 Kumar D, Freese M, Drexler D, Hermans-Borgmeyer I, Marquardt A, Boehm U, Murine arcuate nucleus kisspeptin neurons communicate with GnRH neurons in utero. J Neurosci. 2014 Mar 5;34(10):3756-66
3*J:60130 Kuppers E, Beyer C, Expression of estrogen receptor-alpha and beta mRNA in the developing and adult mouse striatum. Neurosci Lett. 1999 Dec 3;276(2):95-8
2J:162336 La Sala G, Farini D, De Felici M, Rapid estrogen signalling in mouse primordial germ cells. Exp Cell Res. 2010 Jun 10;316(10):1716-27
8*J:54203 Lemmen JG, Broekhof JL, Kuiper GG, Gustafsson JA, van der Saag PT, van der Burg B, Expression of estrogen receptor alpha and beta during mouse embryogenesis. Mech Dev. 1999 Mar;81(1-2):163-7
1J:119922 Mailleux AA, Overholtzer M, Schmelzle T, Bouillet P, Strasser A, Brugge JS, BIM regulates apoptosis during mammary ductal morphogenesis, and its absence reveals alternative cell death mechanisms. Dev Cell. 2007 Feb;12(2):221-34
5J:86854 Moe-Behrens GH, Klinger FG, Eskild W, Grotmol T, Haugen TB, De Felici M, Akt/PTEN Signaling Mediates Estrogen-Dependent Proliferation of Primordial Germ Cells in Vitro. Mol Endocrinol. 2003 Dec;17(12):2630-8
3J:110428 Niakan KK, Davis EC, Clipsham RC, Jiang M, Dehart DB, Sulik KK, McCabe ER, Novel role for the orphan nuclear receptor Dax1 in embryogenesis, different from steroidogenesis. Mol Genet Metab. 2006 Jul;88(3):261-71
5J:60144 Nielsen M, Bjornsdottir S, Hoyer PE, Byskov AG, Ontogeny of oestrogen receptor alpha in gonads and sex ducts of fetal and newborn mice. J Reprod Fertil. 2000 Jan;118(1):195-204
4J:158101 Ogasawara K, Nogami H, Tsuda MC, Gustafsson JA, Korach KS, Ogawa S, Harigaya T, Hisano S, Hormonal regulation of prolactin cell development in the fetal pituitary gland of the mouse. Endocrinology. 2009 Feb;150(2):1061-8
1J:184505 Oliver CH, Khaled WT, Frend H, Nichols J, Watson CJ, The Stat6-regulated KRAB domain zinc finger protein Zfp157 regulates the balance of lineages in mammary glands and compensates for loss of Gata-3. Genes Dev. 2012 May 15;26(10):1086-97
1J:118350 Qin J, Suh JM, Kim BJ, Yu CT, Tanaka T, Kodama T, Tsai MJ, Tsai SY, The expression pattern of nuclear receptors during cerebellar development. Dev Dyn. 2007 Mar;236(3):810-20
2J:118123 Shen J, Liu J, Xie Y, Diwan BA, Waalkes MP, Fetal onset of aberrant gene expression relevant to pulmonary carcinogenesis in lung adenocarcinoma development induced by in utero arsenic exposure. Toxicol Sci. 2007 Feb;95(2):313-20
3J:75909 Shyamala G, Chou YC, Louie SG, Guzman RC, Smith GH, Nandi S, Cellular expression of estrogen and progesterone receptors in mammary glands: regulation by hormones, development and aging. J Steroid Biochem Mol Biol. 2002 Feb;80(2):137-48
1J:28419 Sicinski P, Donaher JL, Parker SB, Li T, Fazeli A, Gardner H, Haslam SZ, Bronson RT, Elledge SJ, Weinberg RA, Cyclin D1 provides a link between development and oncogenesis in the retina and breast. Cell. 1995 Aug 25;82(4):621-30
3J:52383 Tobet SA, Henderson RG, Whiting PJ, Sieghart W, Special relationship of gamma-aminobutyric acid to the ventromedial nucleus of the hypothalamus during embryonic development. J Comp Neurol. 1999 Mar 1;405(1):88-98
1*J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
2J:99320 Wolfe CA, Van Doren M, Walker HJ, Seney ML, McClellan KM, Tobet SA, Sex differences in the location of immunochemically defined cell populations in the mouse preoptic area/anterior hypothalamus. Brain Res Dev Brain Res. 2005 Jun 9;157(1):34-41
9*J:3341 Wu TC, Wang L, Wan YJ, Expression of estrogen receptor gene in mouse oocyte and during embryogenesis. Mol Reprod Dev. 1992 Dec;33(4):407-12
3J:176585 Zheng Z, Cohn MJ, Developmental basis of sexually dimorphic digit ratios. Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16289-94
3J:156703 Zhou B, von Gise A, Ma Q, Hu YW, Pu WT, Genetic fate mapping demonstrates contribution of epicardium-derived cells to the annulus fibrosis of the mammalian heart. Dev Biol. 2010 Feb 15;338(2):251-61

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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory