Gene Expression Literature Summary

• Symbol: Gpc6
• Name: glypican 6
• ID: MGI:1346322

20 matching records from 20 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7	E7.5	E8.5	E9.5	E10	E10.5	E11	E11.5	E12.5	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E18	E18.5	E	P
Immunohistochemistry (section)				1		1		4		2		1		1		1			2
In situ RNA (section)			1	1		1		1		1		1						1		1	2
In situ RNA (whole mount)		1	1	2	1	3								1		1
Northern blot	1						1						1				1				1
Western blot																					1
RT-PCR				1	2	2			1		1	1		3	1						3
cDNA clones														1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Gpc6  glypican 6   (Synonyms: 6720429C22Rik)
Results	Reference
1	J:153618 Ahrens MJ, Li Y, Jiang H, Dudley AT, Convergent extension movements in growth plate chondrocytes require gpi-anchored cell surface proteins. Development. 2009 Oct;136(20):3463-74
1	J:297362 Bachvarova V, Dierker T, Esko J, Hoffmann D, Kjellen L, Vortkamp A, Chondrocytes respond to an altered heparan sulfate composition with distinct changes of heparan sulfate structure and increased levels of chondroitin sulfate. Matrix Biol. 2020 Nov;93:43-59
1	J:230611 Dierker T, Bachvarova V, Krause Y, Li JP, Kjellen L, Seidler DG, Vortkamp A, Altered heparan sulfate structure in Glce(-/-) mice leads to increased Hedgehog signaling in endochondral bones. Matrix Biol. 2016 Jan;49:82-92
1	J:296619 Fan Y, Richelme S, Avazeri E, Audebert S, Helmbacher F, Dono R, Maina F, Tissue-Specific Gain of RTK Signalling Uncovers Selective Cell Vulnerability during Embryogenesis. PLoS Genet. 2015;11(9):e1005533
1*	J:83696 Ford-Perriss M, Turner K, Guimond S, Apedaile A, Haubeck HD, Turnbull J, Murphy M, Localisation of specific heparan sulfate proteoglycans during the proliferative phase of brain development. Dev Dyn. 2003 Jun;227(2):170-84
1	J:292325 Hagey DW, Topcic D, Kee N, Reynaud F, Bergsland M, Perlmann T, Muhr J, CYCLIN-B1/2 and -D1 act in opposition to coordinate cortical progenitor self-renewal and lineage commitment. Nat Commun. 2020 Jun 9;11(1):2898
6	J:149994 Hughes DS, Keynes RJ, Tannahill D, Extensive molecular differences between anterior- and posterior-half-sclerotomes underlie somite polarity and spinal nerve segmentation. BMC Dev Biol. 2009;9:30
2	J:219796 Ko JS, Pramanik G, Um JW, Shim JS, Lee D, Kim KH, Chung GY, Condomitti G, Kim HM, Kim H, de Wit J, Park KS, Tabuchi K, Ko J, PTPsigma functions as a presynaptic receptor for the glypican-4/LRRTM4 complex and is essential for excitatory synaptic transmission. Proc Natl Acad Sci U S A. 2015 Feb 10;112(6):1874-9
7*	J:116479 Luxardi G, Galli A, Forlani S, Lawson K, Maina F, Dono R, Glypicans are differentially expressed during patterning and neurogenesis of early mouse brain. Biochem Biophys Res Commun. 2007 Jan 5;352(1):55-60
2	J:265044 Parras A, Anta H, Santos-Galindo M, Swarup V, Elorza A, Nieto-Gonzalez JL, Pico S, Hernandez IH, Diaz-Hernandez JI, Belloc E, Rodolosse A, Parikshak NN, Penagarikano O, Fernandez-Chacon R, Irimia M, Navarro P, Geschwind DH, Mendez R, Lucas JJ, Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing. Nature. 2018 Aug;560(7719):441-446
1*	J:92177 Powles N, Babbs C, Ficker M, Schimmang T, Maconochie M, Identification and analysis of genes from the mouse otic vesicle and their association with developmental subprocesses through in situ hybridization. Dev Biol. 2004 Apr 1;268(1):24-38
2*	J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188
4	J:331869 Shi W, Filmus J, Glypican-6 and Glypican-4 stimulate embryonic stomach growth by regulating Hedgehog and noncanonical Wnt signaling. Dev Dyn. 2022 Dec;251(12):2015-2028
3	J:298037 Shi W, Kaneiwa T, Cydzik M, Gariepy J, Filmus J, Glypican-6 stimulates intestinal elongation by simultaneously regulating Hedgehog and non-canonical Wnt signaling. Matrix Biol. 2020 Jun;88:19-32
1	J:92208 Takasato M, Osafune K, Matsumoto Y, Kataoka Y, Yoshida N, Meguro H, Aburatani H, Asashima M, Nishinakamura R, Identification of kidney mesenchymal genes by a combination of microarray analysis and Sall1-GFP knockin mice. Mech Dev. 2004 Jun;121(6):547-57
3	J:283457 Uijtdewilligen PJE, Versteeg EM, van de Westerlo EMA, van der Vlag J, Daamen WF, van Kuppevelt TH, Dynamic Expression of Genes Involved in Proteoglycan/Glycosaminoglycan Metabolism during Skin Development. Biomed Res Int. 2018;2018:9873471
8*	J:57579 Veugelers M, De Cat B, Ceulemans H, Bruystens AM, Coomans C, Durr J, Vermeesch J, Marynen P, David G, Glypican-6, a new member of the glypican family of cell surface heparan sulfate proteoglycans. J Biol Chem. 1999 Sep 17;274(38):26968-77
5	J:337768 Wishart TFL, Lovicu FJ, Spatiotemporal Localisation of Heparan Sulphate Proteoglycans throughout Mouse Lens Morphogenesis. Cells. 2023 May 11;12(10)
1*	J:286311 Wu J, Li H, Han L, Sun T, Tian Y, Wang X, The spatiotemporal expression pattern of Syndecans in murine embryonic teeth. Gene Expr Patterns. 2020 Mar 24;36:119109
4*	J:244139 Zhang P, Dimont E, Ha T, Swanson DJ, Hide W, Goldowitz D, Relatively frequent switching of transcription start sites during cerebellar development. BMC Genomics. 2017 Jun 13;18(1):461