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Gene Expression Literature Summary
Symbol
Name
ID
Myh2
myosin, heavy polypeptide 2, skeletal muscle, adult
MGI:1339710

27 matching records from 27 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E4.5 E5.5 E6.5 E7.5 E8.5 E9.5 E10.5 E11.5 E12.5 E13.5 E14 E14.5 E15 E15.5 E16 E16.5 E17 E17.5 E18 E18.5 E19 E19.5 A
In situ protein (section) 1 1 1 3 2 1 2 5 1 10
In situ RNA (section) 1 1 1
Northern blot 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
Western blot 1 1 1 1 1 1 1 1 4
RT-PCR 1 1 2 1 1 1 1 1 4 1 8
cDNA clones 1
RNase protection 1 1 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Myh2  myosin, heavy polypeptide 2, skeletal muscle, adult   (Synonyms: MHC2A, MyHC-IIa, Myhs-f, Myhsf1, Myhs-f1)
Results  Reference
1J:178848 An CI, Dong Y, Hagiwara N, Genome-wide mapping of Sox6 binding sites in skeletal muscle reveals both direct and indirect regulation of muscle terminal differentiation by Sox6. BMC Dev Biol. 2011;11:59
1*J:181685 Bakkar N, Ladner K, Canan BD, Liyanarachchi S, Bal NC, Pant M, Periasamy M, Li Q, Janssen PM, Guttridge DC, IKKalpha and alternative NF-kappaB regulate PGC-1beta to promote oxidative muscle metabolism. J Cell Biol. 2012 Feb 20;196(4):497-511
3J:188916 Brohl D, Vasyutina E, Czajkowski MT, Griger J, Rassek C, Rahn HP, Purfurst B, Wende H, Birchmeier C, Colonization of the satellite cell niche by skeletal muscle progenitor cells depends on Notch signals. Dev Cell. 2012 Sep 11;23(3):469-81
1J:206594 Daou N, Lecolle S, Lefebvre S, della Gaspera B, Charbonnier F, Chanoine C, Armand AS, A new role for the calcineurin/NFAT pathway in neonatal myosin heavy chain expression via the NFATc2/MyoD complex during mouse myogenesis. Development. 2013 Dec;140(24):4914-25
1J:56913 Flucher BE, Conti A, Takeshima H, Sorrentino V, Type 3 and type 1 ryanodine receptors are localized in triads of the same mammalian skeletal muscle fibers. J Cell Biol. 1999 Aug 9;146(3):621-30
4*J:100572 Hagiwara N, Ma B, Ly A, Slow and fast fiber isoform gene expression is systematically altered in skeletal muscle of the Sox6 mutant, p100H. Dev Dyn. 2005 Oct;234(2):301-11
1J:161382 Heude E, Bouhali K, Kurihara Y, Kurihara H, Couly G, Janvier P, Levi G, Jaw muscularization requires Dlx expression by cranial neural crest cells. Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11441-6
1J:108465 Issa LL, Palmer SJ, Guven KL, Santucci N, Hodgson VR, Popovic K, Joya JE, Hardeman EC, MusTRD can regulate postnatal fiber-specific expression. Dev Biol. 2006 May 1;293(1):104-15
5J:60987 Kablar B, Tajbakhsh S, Rudnicki MA, Transdifferentiation of esophageal smooth to skeletal muscle is myogenic bHLH factor-dependent. Development. 2000 Apr;127(8):1627-39
1J:201148 Lee YS, Lee SJ, Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2. Proc Natl Acad Sci U S A. 2013 Sep 24;110(39):E3713-22
10J:58904 Lu BD, Allen DL, Leinwand LA, Lyons GE, Spatial and temporal changes in myosin heavy chain gene expression in skeletal muscle development. Dev Biol. 1999 Dec 1;216(1):312-26
13J:125838 Merrick D, Ting T, Stadler LK, Smith J, A role for Insulin-like growth factor 2 in specification of the fast skeletal muscle fibre. BMC Dev Biol. 2007;7:65
1J:200444 Millay DP, O'Rourke JR, Sutherland LB, Bezprozvannaya S, Shelton JM, Bassel-Duby R, Olson EN, Myomaker is a membrane activator of myoblast fusion and muscle formation. Nature. 2013 Jul 18;499(7458):301-5
4J:100019 Oh M, Rybkin II, Copeland V, Czubryt MP, Shelton JM, van Rooij E, Richardson JA, Hill JA, De Windt LJ, Bassel-Duby R, Olson EN, Rothermel BA, Calcineurin is necessary for the maintenance but not embryonic development of slow muscle fibers. Mol Cell Biol. 2005 Aug;25(15):6629-38
1J:162164 Otto A, Macharia R, Matsakas A, Valasek P, Mankoo BS, Patel K, A hypoplastic model of skeletal muscle development displaying reduced foetal myoblast cell numbers, increased oxidative myofibres and improved specific tension capacity. Dev Biol. 2010 Jul 1;343(1-2):51-62
3J:1896 Parker-Thornburg J, Bauer B, Palermo J, Robbins J, Structural and developmental analysis of two linked myosin heavy chain genes. Dev Biol. 1992 Mar;150(1):99-107
2J:178379 Richard AF, Demignon J, Sakakibara I, Pujol J, Favier M, Strochlic L, Le Grand F, Sgarioto N, Guernec A, Schmitt A, Cagnard N, Huang R, Legay C, Guillet-Deniau I, Maire P, Genesis of muscle fiber-type diversity during mouse embryogenesis relies on Six1 and Six4 gene expression. Dev Biol. 2011 Nov 15;359(2):303-20
1J:125303 Schaeper U, Vogel R, Chmielowiec J, Huelsken J, Rosario M, Birchmeier W, Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo. Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15376-81
1*J:166500 Schoenauer R, Lange S, Hirschy A, Ehler E, Perriard JC, Agarkova I, Myomesin 3, a novel structural component of the M-band in striated muscle. J Mol Biol. 2008 Feb 15;376(2):338-51
3*J:147982 Sehic A, Khuu C, Risnes S, Osmundsen H, Differential gene expression profiling of the molar tooth germ in peroxisome proliferator-activated receptor-alpha (PPAR-alpha) knockout mouse and in wild-type mouse: molar tooth phenotype of PPAR-alpha knockout mouse. Eur J Oral Sci. 2009 Apr;117(2):93-104
1*J:203329 Siles L, Sanchez-Tillo E, Lim JW, Darling DS, Kroll KL, Postigo A, ZEB1 imposes a temporary stage-dependent inhibition of muscle gene expression and differentiation via CtBP-mediated transcriptional repression. Mol Cell Biol. 2013 Apr;33(7):1368-82
2J:32187 Smith TH, Miller JB, Distinct myogenic programs of embryonic and fetal mouse muscle cells: expression of the perinatal myosin heavy chain isoform in vitro. Dev Biol. 1992 Jan;149(1):16-26
4*J:85709 Usami A, Abe S, Ide Y, Myosin heavy chain isoforms of the murine masseter muscle during pre- and post-natal development. Anat Histol Embryol. 2003 Aug;32(4):244-8
1J:155756 van Rooij E, Quiat D, Johnson BA, Sutherland LB, Qi X, Richardson JA, Kelm RJ Jr, Olson EN, A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance. Dev Cell. 2009 Nov;17(5):662-73
16J:103000 Watanabe R, Chano T, Inoue H, Isono T, Koiwai O, Okabe H, Rb1cc1 is critical for myoblast differentiation through Rb1 regulation. Virchows Arch. 2005 Sep;447(3):643-8
2J:136573 Wooldridge AA, Fortner CN, Lontay B, Akimoto T, Neppl RL, Facemire C, Datto MB, Kwon A, McCook E, Li P, Wang S, Thresher RJ, Miller SE, Perriard JC, Gavin TP, Hickner RC, Coffman TM, Somlyo AV, Yan Z, Haystead TA, Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle. J Biol Chem. 2008 Apr 25;283(17):11850-9
2J:26105 Zhang W, Behringer RR, Olson EN, Inactivation of the myogenic bHLH gene MRF4 results in up-regulation of myogenin and rib anomalies. Genes Dev. 1995 Jun 1;9(11):1388-99

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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory