Gene Expression Literature Summary

• Symbol: Mbd3
• Name: methyl-CpG binding domain protein 3
• ID: MGI:1333812

13 matching records from 13 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E1.5	E2	E2.5	E3	E3.5	E4.5	E6.5	E7	E11.5	E12.5	E14.5	E15.5	E16.5	E18.5	P
Immunohistochemistry (section)	1		1		1		1					2	2	1	1	1	2
In situ RNA (section)											1		1	1			1
Immunohistochemistry (whole mount)					1		1	1	1
RT-PCR	2	1	2	2	2	2	2	1				1					1
cDNA clones										1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Mbd3  methyl-CpG binding domain protein 3
Results	Reference
1	J:310811 Chen Y, Damayanti NP, Irudayaraj J, Dunn K, Zhou FC, Diversity of two forms of DNA methylation in the brain. Front Genet. 2014;5:46
1	J:194303 D R D, M R, Mi-2/NuRD is required in renal progenitor cells during embryonic kidney development. Dev Biol. 2013 Mar 15;375(2):105-16
1	J:266522 Elsen GE, Bedogni F, Hodge RD, Bammler TK, MacDonald JW, Lindtner S, Rubenstein JLR, Hevner RF, The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6--> Tbr2--> Tbr1. Front Neurosci. 2018;12:571
1	J:117667 Gu P, Le Menuet D, Chung AC, Cooney AJ, Differential recruitment of methylated CpG binding domains by the orphan receptor GCNF initiates the repression and silencing of Oct4 expression. Mol Cell Biol. 2006 Dec;26(24):9471-83
6*	J:118937 Kaji K, Nichols J, Hendrich B, Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells. Development. 2007 Mar;134(6):1123-32
4	J:222255 Knock E, Pereira J, Lombard PD, Dimond A, Leaford D, Livesey FJ, Hendrich B, The methyl binding domain 3/nucleosome remodelling and deacetylase complex regulates neural cell fate determination and terminal differentiation in the cerebral cortex. Neural Dev. 2015;10:13
1	J:195178 Linke M, May A, Reifenberg K, Haaf T, Zechner U, The impact of ovarian stimulation on the expression of candidate reprogramming genes in mouse preimplantation embryos. Cytogenet Genome Res. 2013;139(2):71-9
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1	J:161421 Mann W, Haaf T, Single cell RT-PCR on mouse embryos: a general approach for developmental biology. Methods Mol Biol. 2010;630:3-12
4*	J:145796 May A, Kirchner R, Muller H, Hartmann P, El Hajj N, Tresch A, Zechner U, Mann W, Haaf T, Multiplex rt-PCR expression analysis of developmentally important genes in individual mouse preimplantation embryos and blastomeres. Biol Reprod. 2009 Jan;80(1):194-202
3	J:244773 Moon BS, Yun HM, Chang WH, Steele BH, Cai M, Choi SH, Lu W, Smek promotes corticogenesis through regulating Mbd3's stability and Mbd3/NuRD complex recruitment to genes associated with neurogenesis. PLoS Biol. 2017 May;15(5):e2001220
10*	J:125227 Reese KJ, Lin S, Verona RI, Schultz RM, Bartolomei MS, Maintenance of paternal methylation and repression of the imprinted H19 gene requires MBD3. PLoS Genet. 2007 Aug 17;3(8):e137
2*	J:174767 Tang F, Barbacioru C, Nordman E, Bao S, Lee C, Wang X, Tuch BB, Heard E, Lao K, Surani MA, Deterministic and stochastic allele specific gene expression in single mouse blastomeres. PLoS One. 2011;6(6):e21208