Gene Expression Literature Summary

• Symbol: Oc90
• Name: otoconin 90
• ID: MGI:1313269

15 matching records from 15 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E9.5	E10	E10.5	E11.5	E12	E12.5	E13.5	E14.5	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E20	P
Immunohistochemistry (section)			1					1	3		2		2			1	4
In situ RNA (section)				1			1	3		1	2		1	1	1		1
In situ RNA (whole mount)	1		1		1	1
Northern blot				1													1
Western blot				1							1						3
RT-PCR		1		2		1	1		1				2				3
cDNA clones												1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Oc90  otoconin 90   (Synonyms: Ocn-95, PLA2L, Pla2ll)
Results	Reference
3*	J:93300 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL, Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
5*	J:263439 Deans MR, Peterson JM, Wong GW, Mammalian Otolin: a multimeric glycoprotein specific to the inner ear that interacts with otoconial matrix protein Otoconin-90 and Cerebellin-1. PLoS One. 2010 Sep 15;5(9):e12765
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
2*	J:82639 Hurle B, Ignatova E, Massironi SM, Mashimo T, Rios X, Thalmann I, Thalmann R, Ornitz DM, Non-syndromic vestibular disorder with otoconial agenesis in tilted/mergulhador mice caused by mutations in otopetrin 1. Hum Mol Genet. 2003 Apr 1;12(7):777-89
7	J:91468 Ignatova EG, Thalmann I, Xu B, Ornitz DM, Thalmann R, Molecular mechanisms underlying ectopic otoconia-like particles in the endolymphatic sac of embryonic mice. Hear Res. 2004 Aug;194(1-2):65-72
2	J:135642 Li S, Mark S, Radde-Gallwitz K, Schlisner R, Chin MT, Chen P, Hey2 functions in parallel with Hes1 and Hes5 for mammalian auditory sensory organ development. BMC Dev Biol. 2008;8:20
1*	J:104332 Lioubinski O, Alonso MT, Alvarez Y, Vendrell V, Garrosa M, Murphy P, Schimmang T, FGF signalling controls expression of vomeronasal receptors during embryogenesis. Mech Dev. 2006 Jan;123(1):17-23
2	J:163712 Marino G, Fernandez AF, Cabrera S, Lundberg YW, Cabanillas R, Rodriguez F, Salvador-Montoliu N, Vega JA, Germana A, Fueyo A, Freije JM, Lopez-Otin C, Autophagy is essential for mouse sense of balance. J Clin Invest. 2010 Jul 1;120(7):2331-44
1	J:71547 Pasqualetti M, Neun R, Davenne M, Rijli FM, Retinoic acid rescues inner ear defects in Hoxa1 deficient mice. Nat Genet. 2001 Sep;29(1):34-9
1	J:338811 Qu F, Li W, Xu J, Zhang R, Ke J, Ren X, Meng X, Qin L, Zhang J, Lu F, Zhou X, Luo X, Zhang Z, Wang M, Wu G, Pei D, Chen J, Cui G, Suo S, Peng G, Three-dimensional molecular architecture of mouse organogenesis. Nat Commun. 2023 Jul 31;14(1):4599
1	J:196582 Romand R, Krezel W, Beraneck M, Cammas L, Fraulob V, Messaddeq N, Kessler P, Hashino E, Dolle P, Retinoic acid deficiency impairs the vestibular function. J Neurosci. 2013 Mar 27;33(13):5856-66
1	J:332093 Szeto IYY, Chu DKH, Chen P, Chu KC, Au TYK, Leung KKH, Huang YH, Wynn SL, Mak ACY, Chan YS, Chan WY, Jauch R, Fritzsch B, Sham MH, Lovell-Badge R, Cheah KSE, SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms. Proc Natl Acad Sci U S A. 2022 Nov 16;119(46):e2122121119
14	J:52192 Verpy E, Leibovici M, Petit C, Characterization of otoconin-95, the major protein of murine otoconia, provides insights into the formation of these inner ear biominerals. Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):529-34
4*	J:237620 Xu Y, Zhang Y, Lundberg YW, Spatiotemporal differences in otoconial gene expression. Genesis. 2016 Dec;54(12):613-625
4*	J:240919 Yang H, Zhao X, Xu Y, Wang L, He Q, Lundberg YW, Matrix recruitment and calcium sequestration for spatial specific otoconia development. PLoS One. 2011;6(5):e20498