Gene Expression Literature Summary

• Symbol: Pcdha4
• Name: protocadherin alpha 4
• ID: MGI:1298406

11 matching records from 11 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E9	E10	E10.5	E13.5	E14	E15	E16.5	E17	E17.5	P
Immunohistochemistry (section)						1	1		2	2
In situ RNA (section)						1			1	3
Northern blot						2				2
Western blot						1		1		2
RT-PCR	1	1	1	1	2	1				3
cDNA clones										1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Pcdha4  protocadherin alpha 4   (Synonyms: Cnr1, Crnr1)
Results	Reference
1	J:269929 Elbert A, Vogt D, Watson A, Levy M, Jiang Y, Brule E, Rowland ME, Rubenstein J, Berube NG, CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons. J Neurosci. 2019 Jan 2;39(1):177-192
3	J:264145 Fan L, Lu Y, Shen X, Shao H, Suo L, Wu Q, Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice. Elife. 2018 Jun 18;7:e35242
1	J:204566 Gendrel AV, Tang YA, Suzuki M, Godwin J, Nesterova TB, Greally JM, Heard E, Brockdorff N, Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes. Mol Cell Biol. 2013 Aug;33(16):3150-65
7*	J:48282 Kohmura N, Senzaki K, Hamada S, Kai N, Yasuda R, Watanabe M , Ishii H , Yasuda M , Mishina M , Yagi T, Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex. Neuron. 1998 Jun;20(6):1137-51
1	J:293992 Mancia Leon WR, Spatazza J, Rakela B, Chatterjee A, Pande V, Maniatis T, Hasenstaub AR, Stryker MP, Alvarez-Buylla A, Clustered gamma-protocadherins regulate cortical interneuron programmed cell death. Elife. 2020 Jul 7;9:e55374
4	J:96852 Morishita H, Kawaguchi M, Murata Y, Seiwa C, Hamada S, Asou H, Yagi T, Myelination triggers local loss of axonal CNR/protocadherin alpha family protein expression. Eur J Neurosci. 2004 Dec;20(11):2843-7
3	J:103707 Morishita H, Murata Y, Esumi S, Hamada S, Yagi T, CNR/Pcdhalpha family in subplate neurons, and developing cortical connectivity. Neuroreport. 2004 Dec 3;15(17):2595-9
3	J:59044 Senzaki K, Ogawa M, Yagi T, Proteins of the CNR family are multiple receptors for Reelin. Cell. 1999 Dec 10;99(6):635-47
4*	J:68765 Takei Y, Hamada S, Senzaki K, Mutoh T, Sugino H, Yagi T, Two novel cnrs from the cnr gene cluster have molecular features distinct from those of cnr1 to 8. Genomics. 2001 Mar 15;72(3):321-30
1*	J:259654 Toyoda S, Kawaguchi M, Kobayashi T, Tarusawa E, Toyama T, Okano M, Oda M, Nakauchi H, Yoshimura Y, Sanbo M, Hirabayashi M, Hirayama T, Hirabayashi T, Yagi T, Developmental epigenetic modification regulates stochastic expression of clustered protocadherin genes, generating single neuron diversity. Neuron. 2014 Apr 2;82(1):94-108
2	J:313451 Xu L, Zheng Y, Li X, Wang A, Huo D, Li Q, Wang S, Luo Z, Liu Y, Xu F, Wu X, Wu M, Zhou Y, Abnormal neocortex arealization and Sotos-like syndrome-associated behavior in Setd2 mutant mice. Sci Adv. 2021 Jan;7(1)