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Gene Expression Literature Summary
Symbol
Name
ID
Snca
synuclein, alpha
MGI:1277151

19 matching records from 19 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E10.5 E11.5 E12 E12.5 E13.5 E14 E14.5 E15 E15.5 E16 E16.5 E17 E18 E18.5 E19 A
In situ protein (section) 1 1 1 1 2 1 2 1 1 1 1 1 2 1 5
In situ RNA (section) 1 1 2 2 1 1 1 6
In situ RNA (whole mount) 1
Northern blot 2
Western blot 1 1 1 1 1 5
RT-PCR 2
cDNA clones 3
RNase protection 1 1 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Snca  synuclein, alpha   (Synonyms: alphaSYN, alpha-synuclein)
Results  Reference
5J:141972 Akil O, Weber CM, Park SN, Ninkina N, Buchman V, Lustig LR, Localization of synucleins in the Mammalian cochlea. J Assoc Res Otolaryngol. 2008 Dec;9(4):452-63
5J:159933 Cano-Jaimez M, Perez-Sanchez F, Milan M, Buendia P, Ambrosio S, Farinas I, Vulnerability of peripheral catecholaminergic neurons to MPTP is not regulated by alpha-synuclein. Neurobiol Dis. 2010 Apr;38(1):92-103
1*J:153971 Giovannone B, Tsiaras WG, de la Monte S, Klysik J, Lautier C, Karashchuk G, Goldwurm S, Smith RJ, GIGYF2 gene disruption in mice results in neurodegeneration and altered insulin-like growth factor signaling. Hum Mol Genet. 2009 Dec 1;18(23):4629-39
6*J:49927 Hong L, Ko HW, Gwag BJ, Joe E, Lee S, Kim YT, Suh YH, The cDNA cloning and ontogeny of mouse alpha-synuclein. Neuroreport. 1998 Apr 20;9(6):1239-43
13J:48620 Hsu LJ, Mallory M, Xia Y, Veinbergs I, Hashimoto M, Yoshimoto M, Thal LJ, Saitoh T, Masliah E, Expression pattern of synucleins (non-Abeta component of Alzheimer's disease amyloid precursor protein/alpha-synuclein) during murine brain development. J Neurochem. 1998 Jul;71(1):338-44
1J:122792 Jacobs FM, Smits SM, Noorlander CW, von Oerthel L, van der Linden AJ, Burbach JP, Smidt MP, Retinoic acid counteracts developmental defects in the substantia nigra caused by Pitx3 deficiency. Development. 2007 Jul;134(14):2673-84
3*J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
2J:125212 Michell AW, Tofaris GK, Gossage H, Tyers P, Spillantini MG, Barker RA, The effect of truncated human alpha-synuclein (1-120) on dopaminergic cells in a transgenic mouse model of Parkinson's disease. Cell Transplant. 2007;16(5):461-74
1J:86439 Ninkina N, Papachroni K, Robertson DC, Schmidt O, Delaney L, O'Neill F, Court F, Rosenthal A, Fleetwood-Walker SM, Davies AM, Buchman VL, Neurons expressing the highest levels of gamma-synuclein are unaffected by targeted inactivation of the gene. Mol Cell Biol. 2003 Nov;23(22):8233-45
1J:150768 Okado H, Ohtaka-Maruyama C, Sugitani Y, Fukuda Y, Ishida R, Hirai S, Miwa A, Takahashi A, Aoki K, Mochida K, Suzuki O, Honda T, Nakajima K, Ogawa M, Terashima T, Matsuda J, Kawano H, Kasai M, The transcriptional repressor RP58 is crucial for cell-division patterning and neuronal survival in the developing cortex. Dev Biol. 2009 Jul 15;331(2):140-51
1J:171698 Pramparo T, Libiger O, Jain S, Li H, Youn YH, Hirotsune S, Schork NJ, Wynshaw-Boris A, Global developmental gene expression and pathway analysis of normal brain development and mouse models of human neuronal migration defects. PLoS Genet. 2011 Mar;7(3):e1001331
1J:92213 Robertson DC, Schmidt O, Ninkina N, Jones PA, Sharkey J, Buchman VL, Developmental loss and resistance to MPTP toxicity of dopaminergic neurones in substantia nigra pars compacta of gamma-synuclein, alpha-synuclein and double alpha/gamma-synuclein null mutant mice. J Neurochem. 2004 Jun;89(5):1126-36
1J:156036 Schilling K, Oberdick J, The treasury of the commons: making use of public gene expression resources to better characterize the molecular diversity of inhibitory interneurons in the cerebellar cortex. Cerebellum. 2009 Dec;8(4):477-89
1J:185964 Sgado P, Ferretti E, Grbec D, Bozzi Y, Simon HH, The atypical homeoprotein Pbx1a participates in the axonal pathfinding of mesencephalic dopaminergic neurons. Neural Dev. 2012;7:24
2J:68925 Simon HH, Saueressig H, Wurst W, Goulding MD, O'Leary DD, Fate of midbrain dopaminergic neurons controlled by the engrailed genes. J Neurosci. 2001 May 1;21(9):3126-34
1J:88592 Smidt MP, Smits SM, Bouwmeester H, Hamers FP, van der Linden AJ, Hellemons AJ, Graw J, Burbach JP, Early developmental failure of substantia nigra dopamine neurons in mice lacking the homeodomain gene Pitx3. Development. 2004 Mar;131(5):1145-55
3*J:136998 Trimarchi JM, Stadler MB, Roska B, Billings N, Sun B, Bartch B, Cepko CL, Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. J Comp Neurol. 2007 Jun 20;502(6):1047-65
2J:195852 Xie Q, Yang Y, Huang J, Ninkovic J, Walcher T, Wolf L, Vitenzon A, Zheng D, Gotz M, Beebe DC, Zavadil J, Cvekl A, Pax6 interactions with chromatin and identification of its novel direct target genes in lens and forebrain. PLoS One. 2013;8(1):e54507
9J:159509 Zhong SC, Luo X, Chen XS, Cai QY, Liu J, Chen XH, Yao ZX, Expression and subcellular location of alpha-synuclein during mouse-embryonic development. Cell Mol Neurobiol. 2010 Apr;30(3):469-82

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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory