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Gene Expression Literature Summary
Symbol
Name
ID
Celsr1
cadherin, EGF LAG seven-pass G-type receptor 1
MGI:1100883

29 matching records from 29 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E5.5 E6.5 E7 E7.5 E8 E8.5 E9 E9.5 E10 E10.5 E11.5 E12 E12.5 E13 E13.5 E14 E14.5 E15 E15.5 E17.5 E18 E18.5 E P
Immunohistochemistry (section) 2 2 1 2 2 2 1 1 4 1 2 1 1 2
In situ RNA (section) 1 2 1 1 2 1 1 1 3 1 1 1 1 1 2
Immunohistochemistry (whole mount) 1 1 1 3 3
In situ RNA (whole mount) 1 1 1 4 2 2 1 3 1 2 1 1 2 1
Western blot 2 1
RT-PCR 1 1 1 1 1 1 1
cDNA clones 1 1 2 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Celsr1  cadherin, EGF LAG seven-pass G-type receptor 1   (Synonyms: Adgrc1, crash, Crsh, Scy)
Results  Reference
1J:239251 Brzoska HL, d'Esposito AM, Kolatsi-Joannou M, Patel V, Igarashi P, Lei Y, Finnell RH, Lythgoe MF, Woolf AS, Papakrivopoulou E, Long DA, Planar cell polarity genes Celsr1 and Vangl2 are necessary for kidney growth, differentiation, and rostrocaudal patterning. Kidney Int. 2016 Dec;90(6):1274-1284
1J:162624 Caddy J, Wilanowski T, Darido C, Dworkin S, Ting SB, Zhao Q, Rank G, Auden A, Srivastava S, Papenfuss TA, Murdoch JN, Humbert PO, Boulos N, Weber T, Zuo J, Cunningham JM, Jane SM, Epidermal wound repair is regulated by the planar cell polarity signaling pathway. Dev Cell. 2010 Jul 20;19(1):138-47
6*J:125765 Crompton LA, Du Roure C, Rodriguez TA, Early embryonic expression patterns of the mouse Flamingo and Prickle orthologues. Dev Dyn. 2007 Nov;236(11):3137-43
3J:84285 Curtin JA, Quint E, Tsipouri V, Arkell RM, Cattanach B, Copp AJ, Henderson DJ, Spurr N, Stanier P, Fisher EM, Nolan PM, Steel KP, Brown SD, Gray IC, Murdoch JN, Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse. Curr Biol. 2003 Jul 1;13(13):1129-33
5J:145627 Devenport D, Fuchs E, Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles. Nat Cell Biol. 2008 Nov;10(11):1257-68
4J:174422 Devenport D, Oristian D, Heller E, Fuchs E, Mitotic internalization of planar cell polarity proteins preserves tissue polarity. Nat Cell Biol. 2011;13(8):893-902
3J:240403 Duncan JS, Stoller ML, Francl AF, Tissir F, Devenport D, Deans MR, Celsr1 coordinates the planar polarity of vestibular hair cells during inner ear development. Dev Biol. 2017 Mar 15;423(2):126-137
1J:242825 Fong KS, Hufnagel RB, Khadka VS, Corley MJ, Maunakea AK, Fogelgren B, Ahmed ZM, Lozanoff S, A mutation in the tuft mouse disrupts TET1 activity and alters the expression of genes that are crucial for neural tube closure. Dis Model Mech. 2016 May 01;9(5):585-96
5*J:72602 Formstone CJ, Little PF, The flamingo-related mouse Celsr family (Celsr1-3) genes exhibit distinct patterns of expression during embryonic development. Mech Dev. 2001 Nov;109(1):91-4
10J:164131 Formstone CJ, Moxon C, Murdoch J, Little P, Mason I, Basal enrichment within neuroepithelia suggests novel function(s) for Celsr1 protein. Mol Cell Neurosci. 2010 Jul;44(3):210-22
1J:139139 Garcia-Garcia MJ, Shibata M, Anderson KV, Chato, a KRAB zinc-finger protein, regulates convergent extension in the mouse embryo. Development. 2008 Sep;135(18):3053-62
1J:235628 Glasco DM, Pike W, Qu Y, Reustle L, Misra K, Di Bonito M, Studer M, Fritzsch B, Goffinet AM, Tissir F, Chandrasekhar A, The atypical cadherin Celsr1 functions non-cell autonomously to block rostral migration of facial branchiomotor neurons in mice. Dev Biol. 2016 Sep 1;417(1):40-9
16*J:51705 Hadjantonakis AK, Formstone CJ, Little PFR, mCelsr1 is an evolutionarily conserved seven-pass transmembrane receptor and is expressed during mouse embryonic development. Mech Dev. 1998 Nov;78(1-2):91-5
4J:43499 Hadjantonakis AK, Sheward WJ, Harmar AJ, de Galan L, Hoovers JM , Little PF, Celsr1, a neural-specific gene encoding an unusual seven-pass transmembrane receptor, maps to mouse chromosome 15 and human chromosome 22qter. Genomics. 1997 Oct 1;45(1):97-104
1J:213915 Kadzik RS, Cohen ED, Morley MP, Stewart KM, Lu MM, Morrisey EE, Wnt ligand/Frizzled 2 receptor signaling regulates tube shape and branch-point formation in the lung through control of epithelial cell shape. Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):12444-9
1J:233664 Luxenburg C, Heller E, Pasolli HA, Chai S, Nikolova M, Stokes N, Fuchs E, Wdr1-mediated cell shape dynamics and cortical tension are essential for epidermal planar cell polarity. Nat Cell Biol. 2015 May;17(5):592-604
1J:194042 Mahaffey JP, Grego-Bessa J, Liem KF Jr, Anderson KV, Cofilin and Vangl2 cooperate in the initiation of planar cell polarity in the mouse embryo. Development. 2013 Mar;140(6):1262-71
1J:240026 Minegishi K, Hashimoto M, Ajima R, Takaoka K, Shinohara K, Ikawa Y, Nishimura H, McMahon AP, Willert K, Okada Y, Sasaki H, Shi D, Fujimori T, Ohtsuka T, Igarashi Y, Yamaguchi TP, Shimono A, Shiratori H, Hamada H, A Wnt5 Activity Asymmetry and Intercellular Signaling via PCP Proteins Polarize Node Cells for Left-Right Symmetry Breaking. Dev Cell. 2017 Mar 13;40(5):439-452.e4
1J:216413 Murdoch JN, Damrau C, Paudyal A, Bogani D, Wells S, Greene ND, Stanier P, Copp AJ, Genetic interactions between planar cell polarity genes cause diverse neural tube defects in mice. Dis Model Mech. 2014 Oct;7(10):1153-63
2*J:163834 Paudyal A, Damrau C, Patterson VL, Ermakov A, Formstone C, Lalanne Z, Wells S, Lu X, Norris DP, Dean CH, Henderson DJ, Murdoch JN, The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear. BMC Dev Biol. 2010;10:87
5J:162560 Qu Y, Glasco DM, Zhou L, Sawant A, Ravni A, Fritzsch B, Damrau C, Murdoch JN, Evans S, Pfaff SL, Formstone C, Goffinet AM, Chandrasekhar A, Tissir F, Atypical cadherins Celsr1-3 differentially regulate migration of facial branchiomotor neurons in mice. J Neurosci. 2010 Jul 14;30(28):9392-401
1*J:202995 Ren DD, Kelly M, Kim SM, Grimsley-Myers CM, Chi FL, Chen P, Testin interacts with vangl2 genetically to regulate inner ear sensory cell orientation and the normal development of the female reproductive tract in mice. Dev Dyn. 2013 Dec;242(12):1454-65
6J:75307 Shima Y, Copeland NG, Gilbert DJ, Jenkins NA, Chisaka O, Takeichi M, Uemura T, Differential expression of the seven-pass transmembrane cadherin genes Celsr1-3 and distribution of the Celsr2 protein during mouse development. Dev Dyn. 2002 Mar;223(3):321-32
4*J:75697 Tissir F, De-Backer O, Goffinet AM, Lambert de Rouvroit C, Developmental expression profiles of Celsr (Flamingo) genes in the mouse. Mech Dev. 2002 Mar;112(1-2):157-60
1J:237534 Wang Y, Baeyens N, Corti F, Tanaka K, Fang JS, Zhang J, Jin Y, Coon B, Hirschi KK, Schwartz MA, Simons M, Syndecan 4 controls lymphatic vasculature remodeling during mouse embryonic development. Development. 2016 Dec 01;143(23):4441-4451
1*J:166958 Yates LL, Papakrivopoulou J, Long DA, Goggolidou P, Connolly JO, Woolf AS, Dean CH, The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation. Hum Mol Genet. 2010 Dec 1;19(23):4663-76
1J:192804 Yates LL, Schnatwinkel C, Hazelwood L, Chessum L, Paudyal A, Hilton H, Romero MR, Wilde J, Bogani D, Sanderson J, Formstone C, Murdoch JN, Niswander LA, Greenfield A, Dean CH, Scribble is required for normal epithelial cell-cell contacts and lumen morphogenesis in the mammalian lung. Dev Biol. 2013 Jan 15;373(2):267-80
3J:159690 Yates LL, Schnatwinkel C, Murdoch JN, Bogani D, Formstone CJ, Townsend S, Greenfield A, Niswander LA, Dean CH, The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis. Hum Mol Genet. 2010 Jun 1;19(11):2251-67
1J:206311 Zhao T, Gan Q, Stokes A, Lassiter RN, Wang Y, Chan J, Han JX, Pleasure DE, Epstein JA, Zhou CJ, beta-catenin regulates Pax3 and Cdx2 for caudal neural tube closure and elongation. Development. 2014 Jan;141(1):148-57

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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory