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Gene Expression Literature Summary
Symbol
Name
ID
Prss12
protease, serine 12 neurotrypsin (motopsin)
MGI:1100881

10 matching records from 10 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E7.5 E8.5 E9 E11 E13 E14.5 E15 E16 E18 E18.5 E20 A
In situ RNA (section) 1 1 3
In situ RNA (whole mount) 1
In situ reporter (knock in) 1
Northern blot 1 1 1 1 1 2
Western blot 1 1 1
RT-PCR 1 1 1 2
cDNA clones 1 1 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Prss12  protease, serine 12 neurotrypsin (motopsin)   (Synonyms: Bssp-3, motopsin)
Results  Reference
3J:209333 Almenar-Queralt A, Kim SN, Benner C, Herrera CM, Kang DE, Garcia-Bassets I, Goldstein LS, Presenilins regulate neurotrypsin gene expression and neurotrypsin-dependent agrin cleavage via cyclic AMP response element-binding protein (CREB) modulation. J Biol Chem. 2013 Dec 6;288(49):35222-36
2*J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
4J:43896 Gschwend TP, Krueger SR, Kozlov SV, Wolfer DP, Sonderegger P, Neurotrypsin, a novel multidomain serine protease expressed in the nervous system. Mol Cell Neurosci. 1997;9(3):207-19
3J:87048 Gu G, Wells JM, Dombkowski D, Preffer F, Aronow B, Melton DA, Global expression analysis of gene regulatory pathways during endocrine pancreatic development. Development. 2004 Jan;131(1):165-79
1J:195324 Hoerder-Suabedissen A, Oeschger FM, Krishnan ML, Belgard TG, Wang WZ, Lee S, Webber C, Petretto E, Edwards AD, Molnar Z, Expression profiling of mouse subplate reveals a dynamic gene network and disease association with autism and schizophrenia. Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3555-60
7J:53919 Iijima N, Tanaka M, Mitsui S, Yamamura Y, Yamaguchi N, Ibata Y, Expression of a serine protease (motopsin PRSS12) mRNA in the mouse brain: in situ hybridization histochemical study. Brain Res Mol Brain Res. 1999 Mar 20;66(1-2):141-9
3*J:137885 Reif R, Sales S, Hettwer S, Dreier B, Gisler C, Wolfel J, Luscher D, Zurlinden A, Stephan A, Ahmed S, Baici A, Ledermann B, Kunz B, Sonderegger P, Specific cleavage of agrin by neurotrypsin, a synaptic protease linked to mental retardation. FASEB J. 2007 Nov;21(13):3468-78
1J:86868 Simon R, Lufkin T, Postnatal lethality in mice lacking the Sax2 homeobox gene homologous to Drosophila S59/slouch: evidence for positive and negative autoregulation. Mol Cell Biol. 2003 Dec;23(24):9046-60
1J:152846 Szabo R, Hobson JP, Christoph K, Kosa P, List K, Bugge TH, Regulation of cell surface protease matriptase by HAI2 is essential for placental development, neural tube closure and embryonic survival in mice. Development. 2009 Aug;136(15):2653-63

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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory