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Gene Expression Literature Summary
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1

35 matching records from 35 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E0.5 E1 E2 E2.5 E3 E3.5 E4 E7 E7.5 E8 E8.5 E9 E10 E10.5 E11 E11.5 E12.5 E13.5 E14 E14.5 E15.5 E16 E16.5 E17 E17.5 E18 E18.5 A
In situ protein (section) 1 3 1 1 5
In situ RNA (section) 1 1 1 2 2 2 1 3 5 2 1 1 1 2 7
In situ protein (whole mount) 1 1 1
In situ RNA (whole mount) 1 1
In situ reporter (knock in) 1 1 1
Northern blot 4
Western blot 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 3 2 1 12
RT-PCR 2 2 1 2 2 1 1 2 2 2 1 2 5

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Pafah1b1  platelet-activating factor acetylhydrolase, isoform 1b, subunit 1   (Synonyms: Lis1, LIS-1, lissencephaly-1 protein, Mdsh, PAF-AH 45, Pafaha)
Results  Reference
8J:37333 Albrecht U, Abu-Issa R, Ratz B, Hattori M, Aoki J, Arai H, Inoue K, Eichele G, Platelet-activating factor acetylhydrolase expression and activity suggest a link between neuronal migration and platelet-activating factor. Dev Biol. 1996 Dec 15;180(2):579-93
2J:137048 Assadi AH, Zhang G, McNeil R, Clark GD, D'Arcangelo G, Pafah1b2 mutations suppress the development of hydrocephalus in compound Pafah1b1; Reln and Pafah1b1; Dab1 mutant mice. Neurosci Lett. 2008 Jul 4;439(1):100-5
3J:69631 Cahana A, Escamez T, Nowakowski RS, Hayes NL, Giacobini M, von Holst A, Shmueli O, Sapir T, McConnell SK, Wurst W, Martinez S, Reiner O, Targeted mutagenesis of Lis1 disrupts cortical development and LIS1 homodimerization. Proc Natl Acad Sci U S A. 2001 May 22;98(11):6429-34
11*J:85521 Cahana A, Jin XL, Reiner O, Wynshaw-Boris A, O'Neill C, A study of the nature of embryonic lethality in LIS1-/- mice. Mol Reprod Dev. 2003 Oct;66(2):134-42
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
8*J:190428 Escamez T, Bahamonde O, Tabares-Seisdedos R, Vieta E, Martinez S, Echevarria D, Developmental dynamics of PAFAH1B subunits during mouse brain development. J Comp Neurol. 2012 Dec 1;520(17):3877-94
2J:66488 Feng Y, Olson EC, Stukenberg PT, Flanagan LA, Kirschner MW, Walsh CA, LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome. Neuron. 2000 Dec;28(3):665-79
1J:82268 Gambello MJ, Darling DL, Yingling J, Tanaka T, Gleeson JG, Wynshaw-Boris A, Multiple dose-dependent effects of Lis1 on cerebral cortical development. J Neurosci. 2003 Mar 1;23(5):1719-29
5J:48093 Isumi H, Takashima S, Ikeda K, Mizuguchi M, Expression of a 45K subunit of platelet-activating factor acetylhydrolase in the developing mouse cerebellum. Anat Embryol (Berl). 1998 May;197(5):415-9
3J:82792 Koizumi H, Yamaguchi N, Hattori M, Ishikawa TO, Aoki J, Taketo MM, Inoue K, Arai H, Targeted disruption of intracellular type I platelet activating factor-acetylhydrolase catalytic subunits causes severe impairment in spermatogenesis. J Biol Chem. 2003 Apr 4;278(14):12489-94
3*J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
5J:47594 Morris SM, Albrecht U, Reiner O, Eichele G, Yu-Lee LY, The lissencephaly gene product Lis1, a protein involved in neuronal migration, interacts with a nuclear movement protein, NudC. Curr Biol. 1998 May 7;8(10):603-6
7J:86720 Nayernia K, Vauti F, Meinhardt A, Cadenas C, Schweyer S, Meyer BI, Schwandt I, Chowdhury K, Engel W, Arnold HH, Inactivation of a testis-specific Lis1 transcript in mice prevents spermatid differentiation and causes male infertility. J Biol Chem. 2003 Nov 28;278(48):48377-85
1J:66487 Niethammer M, Smith DS, Ayala R, Peng J, Ko J, Lee MS, Morabito M, Tsai LH, NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein. Neuron. 2000 Dec;28(3):697-711
2J:178057 Pandey JP, Smith DS, A cdk5-dependent switch regulates lis1/ndel1/dynein-driven organelle transport in adult axons. J Neurosci. 2011 Nov 23;31(47):17207-19
8J:25562 Reiner O, Albrecht U, Gordon M, Chianese KA, Wong C, Gal-Gerber O, Sapir T, Siracusa LD, Buchberg AM, Caskey CT, Eichele G, Lissencephaly gene (LIS1) expression in the CNS suggests a role in neuronal migration. J Neurosci. 1995 May;15(5 Pt 2):3730-8
5*J:57841 Sapir T, Cahana A, Seger R, Nekhai S, Reiner O, LIS1 is a microtubule-associated phosphoprotein. Eur J Biochem. 1999 Oct 1;265(1):181-8
1J:100552 Sasaki S, Mori D, Toyo-oka K, Chen A, Garrett-Beal L, Muramatsu M, Miyagawa S, Hiraiwa N, Yoshiki A, Wynshaw-Boris A, Hirotsune S, Complete loss of Ndel1 results in neuronal migration defects and early embryonic lethality. Mol Cell Biol. 2005 Sep;25(17):7812-27
7J:66505 Sasaki S, Shionoya A, Ishida M, Gambello MJ, Yingling J, Wynshaw-Boris A, Hirotsune S, A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system. Neuron. 2000 Dec;28(3):681-96
4J:159625 Silver DL, Watkins-Chow DE, Schreck KC, Pierfelice TJ, Larson DM, Burnetti AJ, Liaw HJ, Myung K, Walsh CA, Gaiano N, Pavan WJ, The exon junction complex component Magoh controls brain size by regulating neural stem cell division. Nat Neurosci. 2010 May;13(5):551-8
1J:163156 Singh KK, Ge X, Mao Y, Drane L, Meletis K, Samuels BA, Tsai LH, Dixdc1 is a critical regulator of DISC1 and embryonic cortical development. Neuron. 2010 Jul 15;67(1):33-48
1J:195272 Sipe CW, Liu L, Lee J, Grimsley-Myers C, Lu X, Lis1 mediates planar polarity of auditory hair cells through regulation of microtubule organization. Development. 2013 Apr;140(8):1785-95
4*J:53301 Stojanov T, O'Neill C, Ontogeny of expression of a receptor for platelet-activating factor in mouse preimplantation embryos and the effects of fertilization and culture in vitro on its expression. Biol Reprod. 1999 Mar;60(3):674-82
6J:67067 Stojanov T, O'Neill C, In vitro fertilization causes epigenetic modifications to the onset of gene expression from the zygotic genome in mice. Biol Reprod. 2001 Feb;64(2):696-705
1J:77999 Sugitani Y, Nakai S, Minowa O, Nishi M, Jishage K, Kawano H, Mori K, Ogawa M, Noda T, Brn-1 and Brn-2 share crucial roles in the production and positioning of mouse neocortical neurons. Genes Dev. 2002 Jul 15;16(14):1760-5
2J:176963 Sumigray KD, Chen H, Lechler T, Lis1 is essential for cortical microtubule organization and desmosome stability in the epidermis. J Cell Biol. 2011 Aug 22;194(4):631-42
1J:68112 Sweeney KJ, Prokscha A, Eichele G, NudE-L, a novel Lis1-interacting protein, belongs to a family of vertebrate coiled-coil proteins. Mech Dev. 2001 Mar;101(1-2):21-33
3J:171513 Tian Y, Zhang Y, Hurd L, Hannenhalli S, Liu F, Lu MM, Morrisey EE, Regulation of lung endoderm progenitor cell behavior by miR302/367. Development. 2011 Apr;138(7):1235-45
2J:102751 Toyo-Oka K, Sasaki S, Yano Y, Mori D, Kobayashi T, Toyoshima YY, Tokuoka SM, Ishii S, Shimizu T, Muramatsu M, Hiraiwa N, Yoshiki A, Wynshaw-Boris A, Hirotsune S, Recruitment of katanin p60 by phosphorylated NDEL1, an LIS1 interacting protein, is essential for mitotic cell division and neuronal migration. Hum Mol Genet. 2005 Nov 1;14(21):3113-28
2*J:84075 Toyo-oka K, Shionoya A, Gambello MJ, Cardoso C, Leventer R, Ward HL, Ayala R, Tsai LH, Dobyns W, Ledbetter D, Hirotsune S, Wynshaw-Boris A, 14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome. Nat Genet. 2003 Jul;34(3):274-85
1*J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
2J:198233 Wang Y, Lin L, Lai H, Parada LF, Lei L, Transcription factor Sox11 is essential for both embryonic and adult neurogenesis. Dev Dyn. 2013 Jun;242(6):638-53
1J:201674 Xie Y, Juschke C, Esk C, Hirotsune S, Knoblich JA, The phosphatase PP4c controls spindle orientation to maintain proliferative symmetric divisions in the developing neocortex. Neuron. 2013 Jul 24;79(2):254-65
1J:163165 Yano M, Hayakawa-Yano Y, Mele A, Darnell RB, Nova2 regulates neuronal migration through an RNA switch in disabled-1 signaling. Neuron. 2010 Jun 24;66(6):848-58
2J:155113 Zhang X, Lei K, Yuan X, Wu X, Zhuang Y, Xu T, Xu R, Han M, SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice. Neuron. 2009 Oct 29;64(2):173-87

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