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Gene Expression Literature Summary
Symbol
Name
ID
Itga8
integrin alpha 8
MGI:109442

37 matching records from 37 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E3.5 E4 E8.5 E9.5 E11 E11.5 E12.5 E13.5 E14 E14.5 E15 E15.5 E16 E16.5 E17.5 E18 E18.5 E P
Immunohistochemistry (section) 1 2 3 3 4 3 1 3 2 4 3 7 3 1 5 1 11
In situ RNA (section) 1 1 1
Immunohistochemistry (whole mount) 1 1 1 1 1
In situ RNA (whole mount) 1 1 1
In situ reporter (knock in) 1
Western blot 1 1 1 1
RT-PCR 1 1 3 3 1 2 1 2 2 1 1 5

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Itga8  integrin alpha 8  
Results  Reference
2J:208419 Basta JM, Robbins L, Kiefer SM, Dorsett D, Rauchman M, Sall1 balances self-renewal and differentiation of renal progenitor cells. Development. 2014 Mar;141(5):1047-58
2J:180979 Besnard V, Wert SE, Ikegami M, Xu Y, Heffner C, Murray SA, Donahue LR, Whitsett JA, Maternal synchronization of gestational length and lung maturation. PLoS One. 2011;6(11):e26682
1J:70545 Brandenberger R, Schmidt A, Linton J, Wang D, Backus C, Denda S, Muller U, Reichardt LF, Identification and characterization of a novel extracellular matrix protein nephronectin that is associated with integrin alpha8beta1 in the embryonic kidney. J Cell Biol. 2001 Jul 23;154(2):447-58
2J:100575 Carroll TJ, Park JS, Hayashi S, Majumdar A, McMahon AP, Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system. Dev Cell. 2005 Aug;9(2):283-92
2J:195350 Chaen T, Konno T, Egashira M, Bai R, Nomura N, Nomura S, Hirota Y, Sakurai T, Imakawa K, Estrogen-dependent uterine secretion of osteopontin activates blastocyst adhesion competence. PLoS One. 2012;7(11):e48933
3J:131874 Di-Poi N, Zakany J, Duboule D, Distinct Roles and Regulations for Hoxd Genes in Metanephric Kidney Development. PLoS Genet. 2007 Dec 21;3(12):e232
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
3J:152844 Driskell RR, Giangreco A, Jensen KB, Mulder KW, Watt FM, Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis. Development. 2009 Aug;136(16):2815-23
5J:207219 Driskell RR, Lichtenberger BM, Hoste E, Kretzschmar K, Simons BD, Charalambous M, Ferron SR, Herault Y, Pavlovic G, Ferguson-Smith AC, Watt FM, Distinct fibroblast lineages determine dermal architecture in skin development and repair. Nature. 2013 Dec 12;504(7479):277-81
5J:170886 Fujiwara H, Ferreira M, Donati G, Marciano DK, Linton JM, Sato Y, Hartner A, Sekiguchi K, Reichardt LF, Watt FM, The basement membrane of hair follicle stem cells is a muscle cell niche. Cell. 2011 Feb 18;144(4):577-89
4J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457
4J:243840 Gerl K, Steppan D, Fuchs M, Wagner C, Willam C, Kurtz A, Kurt B, Activation of Hypoxia Signaling in Stromal Progenitors Impairs Kidney Development. Am J Pathol. 2017 Jul;187(7):1496-1511
1J:196480 Grisanti L, Clavel C, Cai X, Rezza A, Tsai SY, Sennett R, Mumau M, Cai CL, Rendl M, Tbx18 targets dermal condensates for labeling, isolation, and gene ablation during embryonic hair follicle formation. J Invest Dermatol. 2013 Feb;133(2):344-53
1J:99700 Kiyozumi D, Osada A, Sugimoto N, Weber CN, Ono Y, Imai T, Okada A, Sekiguchi K, Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle. Exp Cell Res. 2005 May 15;306(1):9-23
2J:185210 Kiyozumi D, Takeichi M, Nakano I, Sato Y, Fukuda T, Sekiguchi K, Basement membrane assembly of the integrin alpha8beta1 ligand nephronectin requires Fraser syndrome-associated proteins. J Cell Biol. 2012 May 28;197(5):677-89
1*J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
2J:71581 Kostka G, Giltay R, Bloch W, Addicks K, Timpl R, Fassler R, Chu ML, Perinatal lethality and endothelial cell abnormalities in several vessel compartments of fibulin-1-deficient mice. Mol Cell Biol. 2001 Oct;21(20):7025-34
1J:202344 Lesko MH, Driskell RR, Kretzschmar K, Goldie SJ, Watt FM, Sox2 modulates the function of two distinct cell lineages in mouse skin. Dev Biol. 2013 Oct 1;382(1):15-26
3*J:61486 Littlewood Evans A, Muller U, Stereocilia defects in the sensory hair cells of the inner ear in mice deficient in integrin alpha8beta1. Nat Genet. 2000 Apr;24(4):424-8
6J:38838 Muller U, Wang D, Denda S, Meneses JJ, Pedersen RA, Reichardt LF, Integrin alpha8beta1 is critically important for epithelial-mesenchymal interactions during kidney morphogenesis. Cell. 1997 Mar 7;88(5):603-13
1J:241850 Naiman N, Fujioka K, Fujino M, Valerius MT, Potter SS, McMahon AP, Kobayashi A, Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development. Dev Cell. 2017 May 22;41(4):349-365.e3
1J:267385 O'Brien LL, Combes AN, Short KM, Lindstrom NO, Whitney PH, Cullen-McEwen LA, Ju A, Abdelhalim A, Michos O, Bertram JF, Smyth IM, Little MH, McMahon AP, Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment. Elife. 2018 Dec 5;7
8J:263065 Ogawa T, Li Y, Lua I, Hartner A, Asahina K, Isolation of a unique hepatic stellate cell population expressing integrin alpha8 from embryonic mouse livers. Dev Dyn. 2018 Jun;247(6):867-881
4J:94524 Osada A, Kiyozumi D, Tsutsui K, Ono Y, Weber CN, Sugimoto N, Imai T, Okada A, Sekiguchi K, Expression of MAEG, a novel basement membrane protein, in mouse hair follicle morphogenesis. Exp Cell Res. 2005 Feb 1;303(1):148-59
2J:104891 Osafune K, Takasato M, Kispert A, Asashima M, Nishinakamura R, Identification of multipotent progenitors in the embryonic mouse kidney by a novel colony-forming assay. Development. 2006 Jan;133(1):151-61
4J:234178 Perdigoto CN, Dauber KL, Bar C, Tsai PC, Valdes VJ, Cohen I, Santoriello FJ, Zhao D, Zheng D, Hsu YC, Ezhkova E, Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development. PLoS Genet. 2016 Jul;12(7):e1006151
1J:142530 Pitera JE, Scambler PJ, Woolf AS, Fras1, a basement membrane-associated protein mutated in Fraser syndrome, mediates both the initiation of the mammalian kidney and the integrity of renal glomeruli. Hum Mol Genet. 2008 Dec 15;17(24):3953-64
1J:203162 Ray A, Treloar HB, IgSF8: a developmentally and functionally regulated cell adhesion molecule in olfactory sensory neuron axons and synapses. Mol Cell Neurosci. 2012 Jul;50(3-4):238-49
1J:244798 Recuenco MC, Ohmori T, Tanigawa S, Taguchi A, Fujimura S, Conti MA, Wei Q, Kiyonari H, Abe T, Adelstein RS, Nishinakamura R, Nonmuscle Myosin II Regulates the Morphogenesis of Metanephric Mesenchyme-Derived Immature Nephrons. J Am Soc Nephrol. 2015 May;26(5):1081-91
2J:87910 Scherberich A, Tucker RP, Samandari E, Brown-Luedi M, Martin D, Chiquet-Ehrismann R, Murine tenascin-W: a novel mammalian tenascin expressed in kidney and at sites of bone and smooth muscle development. J Cell Sci. 2004 Feb 1;117(Pt 4):571-81
4J:206836 Taguchi A, Kaku Y, Ohmori T, Sharmin S, Ogawa M, Sasaki H, Nishinakamura R, Redefining the in vivo origin of metanephric nephron progenitors enables generation of complex kidney structures from pluripotent stem cells. Cell Stem Cell. 2014 Jan 2;14(1):53-67
3J:160285 Uchiyama Y, Sakaguchi M, Terabayashi T, Inenaga T, Inoue S, Kobayashi C, Oshima N, Kiyonari H, Nakagata N, Sato Y, Sekiguchi K, Miki H, Araki E, Fujimura S, Tanaka SS, Nishinakamura R, Kif26b, a kinesin family gene, regulates adhesion of the embryonic kidney mesenchyme. Proc Natl Acad Sci U S A. 2010 May 18;107(20):9240-5
2*J:77105 Valerius MT, Patterson LT, Feng Y, Potter SS, Hoxa 11 is upstream of Integrin alpha8 expression in the developing kidney. Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8090-5
7J:85775 Wagner TE, Frevert CW, Herzog EL, Schnapp LM, Expression of the integrin subunit alpha8 in murine lung development. J Histochem Cytochem. 2003 Oct;51(10):1307-15
1J:224386 Wainwright EN, Wilhelm D, Combes AN, Little MH, Koopman P, ROBO2 restricts the nephrogenic field and regulates Wolffian duct-nephrogenic cord separation. Dev Biol. 2015 Aug 15;404(2):88-102
2J:172805 Wang Q, Chow J, Hong J, Smith AF, Moreno C, Seaby P, Vrana P, Miri K, Tak J, Chung ED, Mastromonaco G, Caniggia I, Varmuza S, Recent acquisition of imprinting at the rodent Sfmbt2 locus correlates with insertion of a large block of miRNAs. BMC Genomics. 2011;12:204
1*J:166958 Yates LL, Papakrivopoulou J, Long DA, Goggolidou P, Connolly JO, Woolf AS, Dean CH, The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation. Hum Mol Genet. 2010 Dec 1;19(23):4663-76

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last database update
02/12/2019
MGI 6.13
The Jackson Laboratory