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Gene Expression Literature Summary
Symbol
Name
ID
Mdm4
transformed mouse 3T3 cell double minute 4
MGI:107934

7 matching records from 7 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E7.5 E9.5 E10.5 E11.5 E12.5 E15 E15.5 E16 E17 E18 E18.5 P
Immunohistochemistry (section) 1
In situ RNA (whole mount) 1
Northern blot 1 1 1 1 1 2
Western blot 1 2
RT-PCR 2 1 1 1 3
cDNA clones 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Mdm4  transformed mouse 3T3 cell double minute 4   (Synonyms: 4933417N07Rik, Mdmx)
Results  Reference
3J:174359 Huang L, Yan Z, Liao X, Li Y, Yang J, Wang ZG, Zuo Y, Kawai H, Shadfan M, Ganapathy S, Yuan ZM, The p53 inhibitors MDM2/MDMX complex is required for control of p53 activity in vivo. Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):12001-6
1J:219506 Kim S, Gunesdogan U, Zylicz JJ, Hackett JA, Cougot D, Bao S, Lee C, Dietmann S, Allen GE, Sengupta R, Surani MA, PRMT5 protects genomic integrity during global DNA demethylation in primordial germ cells and preimplantation embryos. Mol Cell. 2014 Nov 20;56(4):564-79
3J:71532 Parant J, Chavez-Reyes A, Little NA, Yan W, Reinke V, Jochemsen AG, Lozano G, Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53. Nat Genet. 2001 Sep;29(1):92-5
7*J:70147 Parant JM, Reinke V, Mims B, Lozano G, Organization, expression, and localization of the murine mdmx gene and pseudogene. Gene. 2001 May 30;270(1-2):277-83
2*J:36053 Shvarts A, Steegenga WT, Riteco N, van Laar T, Dekker P, Bazuine M, van Ham RC, van der Houven van Oordt W, Hateboer G, van der Eb AJ, Jochemsen AG, MDMX: a novel p53-binding protein with some functional properties of MDM2. EMBO J. 1996 Oct 1;15(19):5349-57
5J:213978 Vuong L, Brobst DE, Saadi A, Ivanovic I, Al-Ubaidi MR, Pattern of expression of p53, its family members, and regulators during early ocular development and in the post-mitotic retina. Invest Ophthalmol Vis Sci. 2012 Jul;53(8):4821-31
1J:240406 Zhang Y, Zeng SX, Hao Q, Lu H, Monitoring p53 by MDM2 and MDMX is required for endocrine pancreas development and function in a spatio-temporal manner. Dev Biol. 2017 Mar 01;423(1):34-45

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/10/2017
MGI 6.10
The Jackson Laboratory