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Gene Expression Literature Summary
Symbol
Name
ID
Myh9
myosin, heavy polypeptide 9, non-muscle
MGI:107717

33 matching records from 33 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E5.5 E6.5 E8 E8.5 E9 E9.5 E10.5 E11.5 E12.5 E13 E13.5 E14 E14.5 E15 E15.5 E16 E16.5 E17.5 E18 E18.5 E P
Immunohistochemistry (section) 1 2 1 1 1 3 2 4 4 4 1 8 2 2 1 6 1 1 1 2 9
In situ RNA (section) 2 1 1
Immunohistochemistry (whole mount) 1 2 1
In situ RNA (whole mount) 1 1
In situ reporter (knock in) 1
Western blot 1 1 4 1 1 9
RT-PCR 1 1 1 1 1 1 4
cDNA clones 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Myh9  myosin, heavy polypeptide 9, non-muscle   (Synonyms: D0Jmb2, E030044M24Rik, Fltn, Myhn1, Myhn-1, myosin IIA, NMHC II-A)
Results  Reference
2J:94940 Conti MA, Even-Ram S, Liu C, Yamada KM, Adelstein RS, Defects in cell adhesion and the visceral endoderm following ablation of nonmuscle myosin heavy chain II-A in mice. J Biol Chem. 2004 Oct 1;279(40):41263-6
3J:202224 Crish J, Conti MA, Sakai T, Adelstein RS, Egelhoff TT, Keratin 5-Cre-driven excision of nonmuscle myosin IIA in early embryo trophectoderm leads to placenta defects and embryonic lethality. Dev Biol. 2013 Oct 1;382(1):136-48
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1J:240644 Fan X, Yang H, Kumar S, Tumelty KE, Pisarek-Horowitz A, Rasouly HM, Sharma R, Chan S, Tyminski E, Shamashkin M, Belghasem M, Henderson JM, Coyle AJ, Salant DJ, Berasi SP, Lu W, SLIT2/ROBO2 signaling pathway inhibits nonmuscle myosin IIA activity and destabilizes kidney podocyte adhesion. JCI Insight. 2016 Nov 17;1(19):e86934
3J:90427 Golomb E, Ma X, Jana SS, Preston YA, Kawamoto S, Shoham NG, Goldin E, Conti MA, Sellers JR, Adelstein RS, Identification and characterization of nonmuscle myosin II-C, a new member of the myosin II family. J Biol Chem. 2004 Jan 23;279(4):2800-8
2J:243207 Haque F, Kaku Y, Fujimura S, Ohmori T, Adelstein RS, Nishinakamura R, Non-muscle myosin II deletion in the developing kidney causes ureter-bladder misconnection and apical extrusion of the nephric duct lineage epithelia. Dev Biol. 2017 Jul 01;427(1):121-130
1J:216157 Harunaga JS, Doyle AD, Yamada KM, Local and global dynamics of the basement membrane during branching morphogenesis require protease activity and actomyosin contractility. Dev Biol. 2014 Oct 15;394(2):197-205
3J:222409 Kim S, Lewis AE, Singh V, Ma X, Adelstein R, Bush JO, Convergence and extrusion are required for normal fusion of the mammalian secondary palate. PLoS Biol. 2015 Apr;13(4):e1002122
2J:199510 Lee J, Andreeva A, Sipe CW, Liu L, Cheng A, Lu X, PTK7 regulates myosin II activity to orient planar polarity in the mammalian auditory epithelium. Curr Biol. 2012 Jun 5;22(11):956-66
2J:246153 Logan CM, Rajakaruna S, Bowen C, Radice GL, Robinson ML, Menko AS, N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis. Dev Biol. 2017 Aug 01;428(1):118-134
4J:142122 Lu W, Seeholzer SH, Han M, Arnold AS, Serrano M, Garita B, Philp NJ, Farthing C, Steele P, Chen J, Linask KK, Cellular nonmuscle myosins NMHC-IIA and NMHC-IIB and vertebrate heart looping. Dev Dyn. 2008 Dec;237(12):3577-90
2J:245570 Ma X, Adelstein RS, A point mutation in Myh10 causes major defects in heart development and body wall closure. Circ Cardiovasc Genet. 2014 Jun;7(3):257-65
1J:127463 Ma X, Bao J, Adelstein RS, Loss of cell adhesion causes hydrocephalus in nonmuscle myosin II-B-ablated and mutated mice. Mol Biol Cell. 2007 Jun;18(6):2305-12
2J:92081 Ma X, Kawamoto S, Hara Y, Adelstein RS, A point mutation in the motor domain of nonmuscle myosin II-B impairs migration of distinct groups of neurons. Mol Biol Cell. 2004 Jun;15(6):2568-79
1J:247626 Ma X, Sung DC, Yang Y, Wakabayashi Y, Adelstein RS, Nonmuscle myosin IIB regulates epicardial integrity and epicardium-derived mesenchymal cell maturation. J Cell Sci. 2017 Aug 15;130(16):2696-2706
5J:125412 Maddala R, Skiba N, Vasantha Rao P, Lens fiber cell elongation and differentiation is associated with a robust increase in myosin light chain phosphorylation in the developing mouse. Differentiation. 2007 Oct;75(8):713-25
6J:90712 Marigo V, Nigro A, Pecci A, Montanaro D, Di Stazio M, Balduini CL, Savoia A, Correlation between the clinical phenotype of MYH9-related disease and tissue distribution of class II nonmuscle myosin heavy chains. Genomics. 2004 Jun;83(6):1125-33
1J:203133 Metzis V, Courtney AD, Kerr MC, Ferguson C, Rondon Galeano MC, Parton RG, Wainwright BJ, Wicking C, Patched1 is required in neural crest cells for the prevention of orofacial clefts. Hum Mol Genet. 2013 Dec 15;22(24):5026-35
9J:91334 Mhatre AN, Li J, Kim Y, Coling DE, Lalwani AK, Cloning and developmental expression of nonmuscle myosin IIA (Myh9) in the mammalian inner ear. J Neurosci Res. 2004 May 1;76(3):296-305
4*J:18718 Mieziewska K, Szel A, Van Veen T, Aguirre GD, Philp N, Redistribution of insoluble interphotoreceptor matrix components during photoreceptor differentiation in the mouse retina. J Comp Neurol. 1994 Jul 1;345(1):115-24
3J:187967 Plosa EJ, Gooding KA, Zent R, Prince LS, Nonmuscle myosin II regulation of lung epithelial morphology. Dev Dyn. 2012 Nov;241(11):1770-81
2J:244798 Recuenco MC, Ohmori T, Tanigawa S, Taguchi A, Fujimura S, Conti MA, Wei Q, Kiyonari H, Abe T, Adelstein RS, Nishinakamura R, Nonmuscle Myosin II Regulates the Morphogenesis of Metanephric Mesenchyme-Derived Immature Nephrons. J Am Soc Nephrol. 2015 May;26(5):1081-91
2J:248868 Ridge LA, Mitchell K, Al-Anbaki A, Shaikh Qureshi WM, Stephen LA, Tenin G, Lu Y, Lupu IE, Clowes C, Robertson A, Barnes E, Wright JA, Keavney B, Ehler E, Lovell SC, Kadler KE, Hentges KE, Non-muscle myosin IIB (Myh10) is required for epicardial function and coronary vessel formation during mammalian development. PLoS Genet. 2017 Oct;13(10):e1007068
3J:163649 Sani FV, Kaartinen V, El Shahawy M, Linde A, Gritli-Linde A, Developmental changes in cellular and extracellular structural macromolecules in the secondary palate and in the nasal cavity of the mouse. Eur J Oral Sci. 2010 Jun;118(3):221-36
1J:256230 Shin SW, John Vogt E, Jimenez-Movilla M, Baibakov B, Dean J, Cytoplasmic cleavage of DPPA3 is required for intracellular trafficking and cleavage-stage development in mice. Nat Commun. 2017 Nov 21;8(1):1643
3J:218919 Sumigray K, Zhou K, Lechler T, Cell-cell adhesions and cell contractility are upregulated upon desmosome disruption. PLoS One. 2014;9(7):e101824
6*J:51992 Tsuda T, Majumder K, Linask KK, Differential expression of flectin in the extracellular matrix and left-right asymmetry in mouse embryonic heart during looping stages. Dev Genet. 1998;23(3):203-14
2J:44181 Tullio AN, Accili D, Ferrans VJ, Yu ZX, Takeda K, Grinberg A , Westphal H , Preston YA , Adelstein RS, Nonmuscle myosin II-B is required for normal development of the mouse heart. Proc Natl Acad Sci U S A. 1997 Nov 11;94(23):12407-12
1J:68664 Tullio AN, Bridgman PC, Tresser NJ, Chan CC, Conti MA, Adelstein RS, Hara Y, Structural abnormalities develop in the brain after ablation of the gene encoding nonmuscle myosin II-B heavy chain. J Comp Neurol. 2001 Apr 23;433(1):62-74
3J:163702 Wang A, Ma X, Conti MA, Liu C, Kawamoto S, Adelstein RS, Nonmuscle myosin II isoform and domain specificity during early mouse development. Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14645-50
13J:149532 Yamamoto N, Okano T, Ma X, Adelstein RS, Kelley MW, Myosin II regulates extension, growth and patterning in the mammalian cochlear duct. Development. 2009 Jun;136(12):1977-86
1J:192804 Yates LL, Schnatwinkel C, Hazelwood L, Chessum L, Paudyal A, Hilton H, Romero MR, Wilde J, Bogani D, Sanderson J, Formstone C, Murdoch JN, Niswander LA, Greenfield A, Dean CH, Scribble is required for normal epithelial cell-cell contacts and lumen morphogenesis in the mammalian lung. Dev Biol. 2013 Jan 15;373(2):267-80
1J:159690 Yates LL, Schnatwinkel C, Murdoch JN, Bogani D, Formstone CJ, Townsend S, Greenfield A, Niswander LA, Dean CH, The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis. Hum Mol Genet. 2010 Jun 1;19(11):2251-67

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last database update
05/15/2018
MGI 6.12
The Jackson Laboratory