Gene Expression Literature Summary

• Symbol: Sprr1a
• Name: small proline-rich protein 1A
• ID: MGI:106660

21 matching records from 21 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E	P
Immunohistochemistry (section)			1		1		1	1	1				4
In situ RNA (section)	1		2				2	2	1		1		4
In situ RNA (whole mount)					1	1	1	1		1		1
Northern blot		1				1							1
Western blot				1		1		1		1			1
RT-PCR	1				1		1		1		2		4

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Sprr1a  small proline-rich protein 1A
Results	Reference
1*	J:176660 Abler LL, Keil KP, Mehta V, Joshi PS, Schmitz CT, Vezina CM, A high-resolution molecular atlas of the fetal mouse lower urogenital tract. Dev Dyn. 2011 Oct;240(10):2364-77
1*	J:129949 Cui CY, Kunisada M, Esibizione D, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D, Lymphotoxin-beta regulates periderm differentiation during embryonic skin development. Hum Mol Genet. 2007 Nov 1;16(21):2583-90
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
2*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
3	J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20
12	J:32027 Kartasova T, Darwiche N, Kohno Y, Koizumi H, Osada S, Huh N, Lichti U, Steinert PM, Kuroki T, Sequence and expression patterns of mouse SPR1: Correlation of expression with epithelial function. J Invest Dermatol. 1996 Feb;106(2):294-304
1	J:281366 Liu C, Tate T, Batourina E, Truschel ST, Potter S, Adam M, Xiang T, Picard M, Reiley M, Schneider K, Tamargo M, Lu C, Chen X, He J, Kim H, Mendelsohn CL, Pparg promotes differentiation and regulates mitochondrial gene expression in bladder epithelial cells. Nat Commun. 2019 Oct 9;10(1):4589
5*	J:62093 Marshall D, Hardman MJ, Byrne C, SPRR1 gene induction and barrier formation occur as coordinated moving fronts in terminally differentiating epithelia. J Invest Dermatol. 2000 May;114(5):967-75
1	J:72530 Marshall D, Hardman MJ, Nield KM, Byrne C, Differentially expressed late constituents of the epidermal cornified envelope. Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):13031-6
2*	J:234993 Nishiguchi Y, Ohmoto M, Koki J, Enomoto T, Kominami R, Matsumoto I, Hirota J, Bcl11b/Ctip2 is required for development of lingual papillae in mice. Dev Biol. 2016 Aug 1;416(1):98-110
1	J:292019 Pastore N, Huynh T, Herz NJ, Calcagni' A, Klisch TJ, Brunetti L, Kim KH, De Giorgi M, Hurley A, Carissimo A, Mutarelli M, Aleksieva N, D'Orsi L, Lagor WR, Moore DD, Settembre C, Finegold MJ, Forbes SJ, Ballabio A, TFEB regulates murine liver cell fate during development and regeneration. Nat Commun. 2020 May 18;11(1):2461
1	J:338811 Qu F, Li W, Xu J, Zhang R, Ke J, Ren X, Meng X, Qin L, Zhang J, Lu F, Zhou X, Luo X, Zhang Z, Wang M, Wu G, Pei D, Chen J, Cui G, Suo S, Peng G, Three-dimensional molecular architecture of mouse organogenesis. Nat Commun. 2023 Jul 31;14(1):4599
1*	J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188
1	J:341642 Schwartz B, Levi H, Menon G, Maria R, Upcher A, Kotlovski Y, Oss-Ronen L, Cohen I, ZNF750 Regulates Skin Barrier Function by Driving Cornified Envelope and Lipid Processing Pathways. J Invest Dermatol. 2023 Sep 3;
1	J:283792 Seishima R, Leung C, Yada S, Murad KBA, Tan LT, Hajamohideen A, Tan SH, Itoh H, Murakami K, Ishida Y, Nakamizo S, Yoshikawa Y, Wong E, Barker N, Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development. Nat Commun. 2019 Nov 26;10(1):5378
1	J:297718 Szigety KM, Liu F, Yuan CY, Moran DJ, Horrell J, Gochnauer HR, Cohen RN, Katz JP, Kaestner KH, Seykora JT, Tobias JW, Lazar MA, Xu M, Millar SE, HDAC3 ensures stepwise epidermal stratification via NCoR/SMRT-reliant mechanisms independent of its histone deacetylase activity. Genes Dev. 2020 Jul 1;34(13-14):973-988
1	J:206321 Veniaminova NA, Vagnozzi AN, Kopinke D, Do TT, Murtaugh LC, Maillard I, Dlugosz AA, Reiter JF, Wong SY, Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration. Development. 2013 Dec;140(24):4870-80
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
1*	J:150849 Yu Z, Mannik J, Soto A, Lin KK, Andersen B, The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiation. EMBO J. 2009 Jul 8;28(13):1890-903
7*	J:293298 Zhang M, Wang X, Guo F, Jia Q, Liu N, Chen Y, Yan Y, Huang M, Tang H, Deng Y, Huang S, Zhou Z, Zhang L, Zhang L, Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development. Theranostics. 2019;9(17):5065-5084
1*	J:279933 Zhang X, Wang D, Dongye M, Zhu Y, Chen C, Wang R, Long E, Liu Z, Wu X, Lin D, Chen J, Lin Z, Wang J, Li W, Li Y, Li D, Lin H, Loss-of-function mutations in FREM2 disrupt eye morphogenesis. Exp Eye Res. 2019 Apr;181:302-312