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Gene Expression Literature Summary
Symbol
Name
ID
Mthfr
methylenetetrahydrofolate reductase
MGI:106639

7 matching records from 7 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E8.5 E9.5 E10.5 E11.5 E12.5 E13 E14.5 E15 E15.5 E18 E18.5 P
Immunohistochemistry (section) 1 1 1 1 1 1 1 1 1 2
In situ RNA (section) 1 1 1 1
In situ reporter (knock in) 1 1
RT-PCR 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Mthfr  methylenetetrahydrofolate reductase  
Results  Reference
7J:184371 Cherukad J, Wainwright V, Watson ED, Spatial and temporal expression of folate-related transporters and metabolic enzymes during mouse placental development. Placenta. 2012 May;33(5):440-8
1J:224837 Dutchak PA, Laxman S, Estill SJ, Wang C, Wang Y, Wang Y, Bulut GB, Gao J, Huang LJ, Tu BP, Regulation of Hematopoiesis and Methionine Homeostasis by mTORC1 Inhibitor NPRL2. Cell Rep. 2015 Jul 21;12(3):371-9
4*J:204010 Garner JL, Niles KM, McGraw S, Yeh JR, Cushnie DW, Hermo L, Nagano MC, Trasler JM, Stability of DNA methylation patterns in mouse spermatogonia under conditions of MTHFR deficiency and methionine supplementation. Biol Reprod. 2013 Nov;89(5):125
1*J:147857 Liu SP , Li YS , Chen YJ , Chiang EP , Li AF , Lee YH , Tsai TF , Hsiao M , Huang SF , Chen YM, Glycine N-methyltransferase-/- mice develop chronic hepatitis and glycogen storage disease in the liver. Hepatology. 2007 Nov;46(5):1413-25
3*J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
2J:178814 Pickell L, Wu Q, Wang XL, Leclerc D, Friedman H, Peterson AC, Rozen R, Targeted insertion of two Mthfr promoters in mice reveals temporal- and tissue-specific regulation. Mamm Genome. 2011 Dec;22(11-12):635-47
1*J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory