Gene Expression Literature Summary

• Symbol: Prkar1a
• Name: protein kinase, cAMP dependent regulatory, type I, alpha
• ID: MGI:104878

18 matching records from 18 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E8	E8.5	E9.5	E10	E10.5	E11.5	E12	E12.5	E13.5	E14	E14.5	E15	E16	E16.5	E18	E18.5	E	P
Immunohistochemistry (section)	1											1		1				2
In situ RNA (section)							1	1	1	2	2		2		1	1		3
In situ RNA (whole mount)			1	1	3	1		1	1		1					1		1
Northern blot								1	1		1
Western blot		1				1												2
RT-PCR						1										1		2
cDNA clones																	1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Prkar1a  protein kinase, cAMP dependent regulatory, type I, alpha   (Synonyms: 1300018C22Rik, RIalpha, Tse1, Tse-1)
Results	Reference
1*	J:78010 Amieux PS, Howe DG, Knickerbocker H, Lee DC, Su T, Laszlo GS, Idzerda RL, McKnight GS, Increased basal cAMP-dependent protein kinase activity inhibits the formation of mesoderm-derived structures in the developing mouse embryo. J Biol Chem. 2002 Jul 26;277(30):27294-304
2	J:244906 Berthon A, Faucz FR, Espiard S, Drougat L, Bertherat J, Stratakis CA, Age-dependent effects of Armc5 haploinsufficiency on adrenocortical function. Hum Mol Genet. 2017 Sep 15;26(18):3495-3507
2*	J:280416 Cadd G, McKnight GS, Distinct patterns of cAMP-dependent protein kinase gene expression in mouse brain. Neuron. 1989 Jul;3(1):71-9
1	J:163313 Calo E, Quintero-Estades JA, Danielian PS, Nedelcu S, Berman SD, Lees JA, Rb regulates fate choice and lineage commitment in vivo. Nature. 2010 Aug 26;466(7310):1110-4
8*	J:211302 de Sousa SF, Kawasaki K, Kawasaki M, Volponi AA, Gomez RS, Gomes CC, Sharpe PT, Ohazama A, PKA regulatory subunit expression in tooth development. Gene Expr Patterns. 2014 May;15(1):46-51
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1*	J:259785 Evangelista M, Lim TY, Lee J, Parker L, Ashique A, Peterson AS, Ye W, Davis DP, de Sauvage FJ, Kinome siRNA screen identifies regulators of ciliogenesis and hedgehog signal transduction. Sci Signal. 2008 Sep 30;1(39):ra7
3*	J:25553 Greene RM, Lloyd MR, Uberti M, Nugent P, Pisano MM, Patterns of cyclic AMP-dependent protein kinase gene expression during ontogeny of the murine palate. J Cell Physiol. 1995 Jun;163(3):431-40
2*	J:39210 Huang LJ, Durick K, Weiner JA, Chun J, Taylor SS, Identification of a novel protein kinase A anchoring protein that binds both type I and type II regulatory subunits. J Biol Chem. 1997 Mar 21;272(12):8057-64
8*	J:35122 Imaizumi-Scherrer T, Faust DM, Benichou JC, Hellio R, Weiss MC, Accumulation in fetal muscle and localization to the neuromuscular junction of cAMP-dependent protein kinase A regulatory and catalytic subunits RI alpha and C alpha. J Cell Biol. 1996 Sep;134(5):1241-54
3	J:91318 Mucignat-Caretta C, Caretta A, Regional variations in the localization of insoluble kinase A regulatory isoforms during rodent brain development. J Chem Neuroanat. 2004 Jun;27(3):201-12
1*	J:92177 Powles N, Babbs C, Ficker M, Schimmang T, Maconochie M, Identification and analysis of genes from the mouse otic vesicle and their association with developmental subprocesses through in situ hybridization. Dev Biol. 2004 Apr 1;268(1):24-38
1	J:325352 Sahut-Barnola I, Lefrancois-Martinez AM, Dufour D, Botto JM, Kamilaris C, Faucz FR, Stratakis CA, Val P, Martinez A, Steroidogenic Factor-1 Lineage Origin of Skin Lesions in Carney Complex Syndrome. J Invest Dermatol. 2022 May 12;
1	J:48167 Suzuki Y, Shen T, Poyard M, Best-Belpomme M, Hanoune J, Defer N, Expression of adenylyl cyclase mRNAs in the denervated and in the developing mouse skeletal muscle. Am J Physiol. 1998 Jun;274(6 Pt 1):C1674-85
1	J:58105 Woldeyesus MT, Britsch S, Riethmacher D, Xu L, Sonnenberg-Riethmacher E, Abou-Rebyeh F, Harvey R, Caroni P, Birchmeier C, Peripheral nervous system defects in erbB2 mutants following genetic rescue of heart development. Genes Dev. 1999 Oct 1;13(19):2538-48
2	J:142482 Yin Z, Jones GN, Towns WH 2nd, Zhang X, Abel ED, Binkley PF, Jarjoura D, Kirschner LS, Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis. Circulation. 2008 Mar 18;117(11):1414-22
3*	J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48
1	J:228307 Zhou T, Li J, Zhao P, Liu H, Jia D, Jia H, He L, Cang Y, Boast S, Chen YH, Thibault H, Scherrer-Crosbie M, Goff SP, Li B, Palmitoyl acyltransferase Aph2 in cardiac function and the development of cardiomyopathy. Proc Natl Acad Sci U S A. 2015 Dec 22;112(51):15666-71