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Gene Expression Literature Summary
Symbol
Name
ID
Ppara
peroxisome proliferator activated receptor alpha
MGI:104740

35 matching records from 35 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E0.5 E1 E1.5 E2 E2.5 E3 E3.5 E4.5 E5 E5.5 E6.5 E7.5 E8.5 E9.5 E10.5 E11 E11.5 E12.5 E13 E13.5 E14.5 E15 E15.5 E16.5 E17 E17.5 E18 E18.5 E19 E19.5 A
In situ RNA (section) 1 1 3 3 3 2 2 2 1 5
In situ RNA (whole mount) 1 1
Northern blot 1 1 1 1 1 1 1 2 2 3 3
Western blot 1 2 1 1 1 2
RT-PCR 3 1 1 2 3 1 4 2 1 1 1 1 1 1 1 1 2 1 2 2 2 3 2 4 1 17
RNase protection 1 1 1 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Ppara  peroxisome proliferator activated receptor alpha   (Synonyms: 4933429D07Rik, Nr1c1, Ppar, PPARalpha, PPAR-alpha)
Results  Reference
6J:186530 Abbott BD, Wood CR, Watkins AM, Tatum-Gibbs K, Das KP, Lau C, Effects of perfluorooctanoic acid (PFOA) on expression of peroxisome proliferator-activated receptors (PPAR) and nuclear receptor-regulated genes in fetal and postnatal CD-1 mouse tissues. Reprod Toxicol. 2012 Jul;33(4):491-505
9J:2943 Beck F, Plummer S, Senior PV, Byrne S, Green S, Brammar WJ, The ontogeny of peroxisome-proliferator-activated receptor gene expression in the mouse and rat. Proc R Soc Lond B Biol Sci. 1992 Feb 22;247(1319):83-7
4J:188330 Benezech C, Mader E, Desanti G, Khan M, Nakamura K, White A, Ware CF, Anderson G, Caamano JH, Lymphotoxin-beta Receptor Signaling through NF-kappaB2-RelB Pathway Reprograms Adipocyte Precursors as Lymph Node Stromal Cells. Immunity. 2012 Oct 19;37(4):721-34
1J:180603 Bertrand AT, Renou L, Papadopoulos A, Beuvin M, Lacene E, Massart C, Ottolenghi C, Decostre V, Maron S, Schlossarek S, Cattin ME, Carrier L, Malissen M, Arimura T, Bonne G, DelK32-lamin A/C has abnormal location and induces incomplete tissue maturation and severe metabolic defects leading to premature death. Hum Mol Genet. 2012 Mar 1;21(5):1037-48
1J:201804 Breckenridge RA, Piotrowska I, Ng KE, Ragan TJ, West JA, Kotecha S, Towers N, Bennett M, Kienesberger PC, Smolenski RT, Siddall HK, Offer JL, Mocanu MM, Yelon DM, Dyck JR, Griffin JL, Abramov AY, Gould AP, Mohun TJ, Hypoxic regulation of hand1 controls the fetal-neonatal switch in cardiac metabolism. PLoS Biol. 2013 Sep;11(9):e1001666
1J:106993 Briancon N, Weiss MC, In vivo role of the HNF4alpha AF-1 activation domain revealed by exon swapping. EMBO J. 2006 Mar 22;25(6):1253-62
1J:163313 Calo E, Quintero-Estades JA, Danielian PS, Nedelcu S, Berman SD, Lees JA, Rb regulates fate choice and lineage commitment in vivo. Nature. 2010 Aug 26;466(7310):1110-4
3*J:76945 Carmona MC, Iglesias R, Obregon MJ, Darlington GJ, Villarroya F, Giralt M, Mitochondrial biogenesis and thyroid status maturation in brown fat require CCAAT/enhancer-binding protein alpha. J Biol Chem. 2002 Jun 14;277(24):21489-98
1J:182286 Charalambous M, Ferron SR, da Rocha ST, Murray AJ, Rowland T, Ito M, Schuster-Gossler K, Hernandez A, Ferguson-Smith AC, Imprinted gene dosage is critical for the transition to independent life. Cell Metab. 2012 Feb 8;15(2):209-21
4J:119560 Choi MY, Romer AI, Hu M, Lepourcelet M, Mechoor A, Yesilaltay A, Krieger M, Gray PA, Shivdasani RA, A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development. Development. 2006 Oct;133(20):4119-29
2*J:168654 Chung YC, Tsai YJ, Shiu TY, Sun YY, Wang PF, Chen CL, Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):84-92
3*J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
1*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. http://www.gudmap.org. 2004;
7*J:140465 Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND, Robson P, Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Dev Cell. 2010 Apr 20;18(4):675-85
4J:154032 Guo Y, Zhang X, Huang J, Zeng Y, Liu W, Geng C, Li KW, Yang D, Wu S, Wei H, Han Z, Qian X, Jiang Y, He F, Relationships between hematopoiesis and hepatogenesis in the midtrimester fetal liver characterized by dynamic transcriptomic and proteomic profiles. PLoS One. 2009;4(10):e7641
3*J:165681 Hall JA, Ribich S, Christoffolete MA, Simovic G, Correa-Medina M, Patti ME, Bianco AC, Absence of thyroid hormone activation during development underlies a permanent defect in adaptive thermogenesis. Endocrinology. 2010 Sep;151(9):4573-82
1J:213153 Harms MJ, Ishibashi J, Wang W, Lim HW, Goyama S, Sato T, Kurokawa M, Won KJ, Seale P, Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice. Cell Metab. 2014 Apr 1;19(4):593-604
1J:115995 Horsley V, O'Carroll D, Tooze R, Ohinata Y, Saitou M, Obukhanych T, Nussenzweig M, Tarakhovsky A, Fuchs E, Blimp1 defines a progenitor population that governs cellular input to the sebaceous gland. Cell. 2006 Aug 11;126(3):597-609
1J:162597 Hyvarinen J, Hassinen IE, Sormunen R, Maki JM, Kivirikko KI, Koivunen P, Myllyharju J, Hearts of hypoxia-inducible factor prolyl 4-hydroxylase-2 hypomorphic mice show protection against acute ischemia-reperfusion injury. J Biol Chem. 2010 Apr 30;285(18):13646-57
4J:194010 Iglesias J, Barg S, Vallois D, Lahiri S, Roger C, Yessoufou A, Pradevand S, McDonald A, Bonal C, Reimann F, Gribble F, Debril MB, Metzger D, Chambon P, Herrera P, Rutter GA, Prentki M, Thorens B, Wahli W, PPARbeta/delta affects pancreatic beta cell mass and insulin secretion in mice. J Clin Invest. 2012 Nov 1;122(11):4105-17
3J:152500 Jansen S, Cashman K, Thompson JG, Pantaleon M, Kaye PL, Glucose deprivation, oxidative stress and peroxisome proliferator-activated receptor-alpha (PPARA) cause peroxisome proliferation in preimplantation mouse embryos. Reproduction. 2009 Sep;138(3):493-505
8*J:189008 Jia Y, Viswakarma N, Crawford SE, Sarkar J, Sambasiva Rao M, Karpus WJ, Kanwar YS, Zhu YJ, Reddy JK, Early embryonic lethality of mice with disrupted transcription cofactor PIMT/NCOA6IP/Tgs1 gene. Mech Dev. 2012 Sep;129(9-12):193-207
9J:170133 Kim ST, Marquard K, Stephens S, Louden E, Allsworth J, Moley KH, Adiponectin and adiponectin receptors in the mouse preimplantation embryo and uterus. Hum Reprod. 2011 Jan;26(1):82-95
10*J:19422 Kliewer SA, Forman BM, Blumberg B, Ong ES, Borgmeyer U, Mangelsdorf DJ, Umesono K, Evans RM, Differential expression and activation of a family of murine peroxisome proliferator-activated receptors. Proc Natl Acad Sci U S A. 1994 Jul 19;91(15):7355-9
2J:198622 Landrock D, Atshaves BP, McIntosh AL, Landrock KK, Schroeder F, Kier AB, Acyl-CoA binding protein gene ablation induces pre-implantation embryonic lethality in mice. Lipids. 2010 Jul;45(7):567-80
3*J:65091 Lehman JJ, Barger PM, Kovacs A, Saffitz JE, Medeiros DM, Kelly DP, Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis. J Clin Invest. 2000 Oct;106(7):847-56
2J:56144 Lim H, Gupta RA, Ma WG, Paria BC, Moller DE, Morrow JD, DuBois RN, Trzaskos JM, Dey SK, Cyclo-oxygenase-2-derived prostacyclin mediates embryo implantation in the mouse via PPARdelta. Genes Dev. 1999 Jun 15;13(12):1561-74
12J:71272 Michalik L, Desvergne B, Tan NS, Basu-Modak S, Escher P, Rieusset J, Peters JM, Kaya G, Gonzalez FJ, Zakany J, Metzger D, Chambon P, Duboule D, Wahli W, Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)alpha and PPARbeta mutant mice. J Cell Biol. 2001 Aug 20;154(4):799-814
1*J:60554 Nohammer C, El-Shabrawi Y, Schauer S, Hiden M, Berger J, Forss-Petter S, Winter E, Eferl R, Zechner R, Hoefler G, cDNA cloning and analysis of tissue-specific expression of mouse peroxisomal straight-chain acyl-CoA oxidase. Eur J Biochem. 2000 Feb;267(4):1254-60
1J:198125 Rajakumari S, Wu J, Ishibashi J, Lim HW, Giang AH, Won KJ, Reed RR, Seale P, EBF2 determines and maintains brown adipocyte identity. Cell Metab. 2013 Apr 2;17(4):562-74
1*J:40975 Sack MN, Disch DL, Rockman HA, Kelly DP, A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth program. Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6438-43
1J:129766 Sano M, Izumi Y, Helenius K, Asakura M, Rossi DJ, Xie M, Taffet G, Hu L, Pautler RG, Wilson CR, Boudina S, Abel ED, Taegtmeyer H, Scaglia F, Graham BH, Kralli A, Shimizu N, Tanaka H, Makela TP, Schneider MD, Menage-a-trois 1 is critical for the transcriptional function of PPARgamma coactivator 1. Cell Metab. 2007 Feb;5(2):129-42
2J:136733 Schmidt T, Fischer S, Tsikolia N, Navarrete Santos A, Rohrbach S, Ramin N, Thieme R, Fischer B, Expression of adipokines in preimplantation rabbit and mice embryos. Histochem Cell Biol. 2008 Jun;129(6):817-25
2J:138822 Tseng YH, Kokkotou E, Schulz TJ, Huang TL, Winnay JN, Taniguchi CM, Tran TT, Suzuki R, Espinoza DO, Yamamoto Y, Ahrens MJ, Dudley AT, Norris AW, Kulkarni RN, Kahn CR, New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure. Nature. 2008 Aug 21;454(7207):1000-4
1*J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6

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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory