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Gene Expression Literature Summary
Symbol
Name
ID
Ndst1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
MGI:104719

11 matching records from 11 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E7 E9.5 E10 E11 E11.5 E12 E12.5 E14 E14.5 E15 E16 E16.5 E17.5 E18.5 E P
Immunohistochemistry (section) 1
In situ RNA (section) 1 1 2 1 2
In situ RNA (whole mount) 1
Northern blot 1
Western blot 1
RT-PCR 1 1 1 1 1 1 1 1 1 1 2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Ndst1  N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1   (Synonyms: 1200015G06Rik, b2b2230Clo, glucosaminyl N-deacetylase/N-sulfotransferase 1, Hsst, Ndst-1)
Results  Reference
4*J:67535 Aikawa J, Grobe K, Tsujimoto M, Esko JD, Multiple isozymes of heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase. Structure and activity of the fourth member, NDST4. J Biol Chem. 2001 Feb 23;276(8):5876-82
1*J:178840 Dagalv A, Holmborn K, Kjellen L, Abrink M, Lowered expression of heparan sulfate/heparin biosynthesis enzyme N-deacetylase/n-sulfotransferase 1 results in increased sulfation of mast cell heparin. J Biol Chem. 2011 Dec 30;286(52):44433-40
3*J:81601 Ford-Perriss M, Guimond SE, Greferath U, Kita M, Grobe K, Habuchi H, Kimata K, Esko JD, Murphy M, Turnbull JE, Variant heparan sulfates synthesized in developing mouse brain differentially regulate FGF signaling. Glycobiology. 2002 Nov;12(11):721-7
3J:100425 Grobe K, Inatani M, Pallerla SR, Castagnola J, Yamaguchi Y, Esko JD, Cerebral hypoplasia and craniofacial defects in mice lacking heparan sulfate Ndst1 gene function. Development. 2005 Aug;132(16):3777-86
1J:150516 Hu Z, Wang C, Xiao Y, Sheng N, Chen Y, Xu Y, Zhang L, Mo W, Jing N, Hu G, NDST1-dependent heparan sulfate regulates BMP signaling and internalization in lung development. J Cell Sci. 2009 Apr 15;122(Pt 8):1145-54
1J:138557 Pallerla SR, Lawrence R, Lewejohann L, Pan Y, Fischer T, Schlomann U, Zhang X, Esko JD, Grobe K, Altered heparan sulfate structure in mice with deleted NDST3 gene function. J Biol Chem. 2008 Jun 13;283(24):16885-94
1J:130571 Pan Y, Carbe C, Powers A, Zhang EE, Esko JD, Grobe K, Feng GS, Zhang X, Bud specific N-sulfation of heparan sulfate regulates Shp2-dependent FGF signaling during lacrimal gland induction. Development. 2008 Jan;135(2):301-10
3J:119651 Pan Y, Woodbury A, Esko JD, Grobe K, Zhang X, Heparan sulfate biosynthetic gene Ndst1 is required for FGF signaling in early lens development. Development. 2006 Dec;133(24):4933-44
1J:63996 Ringvall M, Ledin J, Holmborn K, van Kuppevelt T, Ellin F, Eriksson I, Olofsson AM, Kjellen L, Forsberg E, Defective heparan sulfate biosynthesis and neonatal lethality in mice lacking N-deacetylase/N-sulfotransferase-1. J Biol Chem. 2000 Aug 25;275(34):25926-30
1*J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
4*J:103005 Yabe T, Hata T, He J, Maeda N, Developmental and regional expression of heparan sulfate sulfotransferase genes in the mouse brain. Glycobiology. 2005 Oct;15(10):982-93

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last database update
02/12/2019
MGI 6.13
The Jackson Laboratory