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Gene Expression Literature Summary
Symbol
Name
ID
Crkl
v-crk avian sarcoma virus CT10 oncogene homolog-like
MGI:104686

16 matching records from 16 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E8.5 E9 E9.5 E10 E10.5 E11.5 E12 E12.5 E13.5 E14 E14.5 E15.5 E16.5 E17.5 E18 E18.5 P
Immunohistochemistry (section) 1 1 1
In situ RNA (section) 1 1 1
Immunohistochemistry (whole mount) 1 1 1
In situ RNA (whole mount) 1 1 1 1
Western blot 1 3 1 1 1 1 1
RT-PCR 1 1 1 2 4 1 1 1 1 1
cDNA clones 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Crkl  v-crk avian sarcoma virus CT10 oncogene homolog-like   (Synonyms: 1110025F07Rik, Crkol, snoop)
Results  Reference
2J:213829 Bard-Chapeau EA, Szumska D, Jacob B, Chua BQ, Chatterjee GC, Zhang Y, Ward JM, Urun F, Kinameri E, Vincent SD, Ahmed S, Bhattacharya S, Osato M, Perkins AS, Moore AW, Jenkins NA, Copeland NG, Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects. PLoS One. 2014;9(2):e89397
6*J:29533 de Jong R, Haataja L, Voncken JW, Heisterkamp N, Groffen J, Tyrosine phosphorylation of murine Crkl. Oncogene. 1995 Oct 19;11(8):1469-74
1*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
3J:67826 Guris DL, Fantes J, Tara D, Druker BJ, Imamoto A, Mice lacking the homologue of the human 22q11.2 gene CRKL phenocopy neurocristopathies of DiGeorge syndrome. Nat Genet. 2001 Mar;27(3):293-8
2J:242224 Haller M, Mo Q, Imamoto A, Lamb DJ, Murine model indicates 22q11.2 signaling adaptor CRKL is a dosage-sensitive regulator of genitourinary development. Proc Natl Acad Sci U S A. 2017 May 09;114(19):4981-4986
2J:165470 Hallock PT, Xu CF, Park TJ, Neubert TA, Curran T, Burden SJ, Dok-7 regulates neuromuscular synapse formation by recruiting Crk and Crk-L. Genes Dev. 2010 Nov 1;24(21):2451-61
1J:182094 Huang ZP, Chen JF, Regan JN, Maguire CT, Tang RH, Dong XR, Majesky MW, Wang DZ, Loss of microRNAs in neural crest leads to cardiovascular syndromes resembling human congenital heart defects. Arterioscler Thromb Vasc Biol. 2010 Dec;30(12):2575-86
3*J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
6*J:86704 Maynard TM, Haskell GT, Peters AZ, Sikich L, Lieberman JA, LaMantia AS, A comprehensive analysis of 22q11 gene expression in the developing and adult brain. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14433-8
3J:251775 Miller KA, Tan TY, Welfare MF, White SM, Stark Z, Savarirayan R, Burgess T, Heggie AA, Caruana G, Bertram JF, Bateman JF, Farlie PG, A mouse splice-site mutant and individuals with atypical chromosome 22q11.2 deletions demonstrate the crucial role for crkl in craniofacial and pharyngeal development. Mol Syndromol. 2014 Dec;5(6):276-86
2*J:98850 Prescott K, Ivins S, Hubank M, Lindsay E, Baldini A, Scambler P, Microarray analysis of the Df1 mouse model of the 22q11 deletion syndrome. Hum Genet. 2005 May;116(6):486-96
1*J:230261 Racedo SE, McDonald-McGinn DM, Chung JH, Goldmuntz E, Zackai E, Emanuel BS, Zhou B, Funke B, Morrow BE, Mouse and human CRKL is dosage sensitive for cardiac outflow tract formation. Am J Hum Genet. 2015 Feb 5;96(2):235-44
1J:229358 Teo ZL, McQueen-Miscamble L, Turner K, Martinez G, Madakashira B, Dedhar S, Robinson ML, de Iongh RU, Integrin linked kinase (ILK) is required for lens epithelial cell survival, proliferation and differentiation. Exp Eye Res. 2014 Apr;121:130-42
1J:152558 Vallejo-Illarramendi A, Zang K, Reichardt LF, Focal adhesion kinase is required for neural crest cell morphogenesis during mouse cardiovascular development. J Clin Invest. 2009 Aug;119(8):2218-30
1J:188772 Voss AK, Vanyai HK, Collin C, Dixon MP, McLennan TJ, Sheikh BN, Scambler P, Thomas T, MOZ regulates the Tbx1 locus, and Moz mutation partially phenocopies DiGeorge syndrome. Dev Cell. 2012 Sep 11;23(3):652-63
2J:132843 Yip YP, Kronstadt-O'Brien P, Capriotti C, Cooper JA, Yip JW, Migration of sympathetic preganglionic neurons in the spinal cord is regulated by Reelin-dependent Dab1 tyrosine phosphorylation and CrkL. J Comp Neurol. 2007 Jun 1;502(4):635-43

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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory