Gene Expression Literature Summary

• Symbol: Madcam1
• Name: mucosal vascular addressin cell adhesion molecule 1
• ID: MGI:103579

30 matching records from 30 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E12.5	E13.5	E14	E14.5	E15.5	E16	E16.5	E17.5	E18	E18.5	E19.5	E20	E	P
Immunohistochemistry (section)		2		6	2		8	5	1	6	1		1	12
In situ RNA (section)				2
Immunohistochemistry (whole mount)	1	2	1	1	2	1	1		1	1		1
RT-PCR										1			1	1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Madcam1  mucosal vascular addressin cell adhesion molecule 1   (Synonyms: MGC:35998)
Results	Reference
1	J:188330 Benezech C, Mader E, Desanti G, Khan M, Nakamura K, White A, Ware CF, Anderson G, Caamano JH, Lymphotoxin-beta Receptor Signaling through NF-kappaB2-RelB Pathway Reprograms Adipocyte Precursors as Lymph Node Stromal Cells. Immunity. 2012 Oct 19;37(4):721-34
2	J:159868 Benezech C, White A, Mader E, Serre K, Parnell S, Pfeffer K, Ware CF, Anderson G, Caamano JH, Ontogeny of stromal organizer cells during lymph node development. J Immunol. 2010 Apr 15;184(8):4521-30
1*	J:291925 Bennion BG, Croft CA, Ai TL, Qian W, Menos AM, Miner CA, Fremond ML, Doisne JM, Andhey PS, Platt DJ, Bando JK, Wang ER, Luksch H, Molina TJ, Roberson EDO, Artyomov MN, Rosen-Wolff A, Colonna M, Rieux-Laucat F, Di Santo JP, Neven B, Miner JJ, STING Gain-of-Function Disrupts Lymph Node Organogenesis and Innate Lymphoid Cell Development in Mice. Cell Rep. 2020 Jun 16;31(11):107771
2	J:269938 Bovay E, Sabine A, Prat-Luri B, Kim S, Son K, Willrodt AH, Olsson C, Halin C, Kiefer F, Betsholtz C, Jeon NL, Luther SA, Petrova TV, Multiple roles of lymphatic vessels in peripheral lymph node development. J Exp Med. 2018 Nov 5;215(11):2760-2777
1	J:196959 Castagnaro L, Lenti E, Maruzzelli S, Spinardi L, Migliori E, Farinello D, Sitia G, Harrelson Z, Evans SM, Guidotti LG, Harvey RP, Brendolan A, Nkx2-5(+)islet1(+) mesenchymal precursors generate distinct spleen stromal cell subsets and participate in restoring stromal network integrity. Immunity. 2013 Apr 18;38(4):782-91
2	J:286704 Cheng HW, Onder L, Novkovic M, Soneson C, Lutge M, Pikor N, Scandella E, Robinson MD, Miyazaki JI, Tersteegen A, Sorg U, Pfeffer K, Rulicke T, Hehlgans T, Ludewig B, Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp. Nat Commun. 2019 Apr 15;10(1):1739
1	J:248815 Cordeiro OG, Chypre M, Brouard N, Rauber S, Alloush F, Romera-Hernandez M, Benezech C, Li Z, Eckly A, Coles MC, Rot A, Yagita H, Leon C, Ludewig B, Cupedo T, Lanza F, Mueller CG, Integrin-Alpha IIb Identifies Murine Lymph Node Lymphatic Endothelial Cells Responsive to RANKL. PLoS One. 2016;11(3):e0151848
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:310429 Furtado GC, Pacer ME, Bongers G, Benezech C, He Z, Chen L, Berin MC, Kollias G, Caamano JH, Lira SA, TNFalpha-dependent development of lymphoid tissue in the absence of RORgammat+ lymphoid tissue inducer cells. Mucosal Immunol. 2014;7(3):602-14
1	J:239279 Kidoya H, Naito H, Muramatsu F, Yamakawa D, Jia W, Ikawa M, Sonobe T, Tsuchimochi H, Shirai M, Adams RH, Fukamizu A, Takakura N, APJ Regulates Parallel Alignment of Arteries and Veins in the Skin. Dev Cell. 2015 May 04;33(3):247-59
2	J:324834 Lenti E, Genovese L, Bianchessi S, Maurizio A, Sain SB, di Lillo A, Mattavelli G, Harel I, Bernassola F, Hehlgans T, Pfeffer K, Crosti M, Abrignani S, Evans SM, Sitia G, Guimaraes-Camboa N, Russo V, van de Pavert SA, Garcia-Manteiga JM, Brendolan A, Fate mapping and scRNA sequencing reveal origin and diversity of lymph node stromal precursors. Immunity. 2022 Apr 12;55(4):606-622.e6
1	J:98335 Mok H, Mendoza M, Prchal JT, Balogh P, Schumacher A, Dysregulation of ferroportin 1 interferes with spleen organogenesis in polycythaemia mice. Development. 2004 Oct;131(19):4871-81
1	J:77350 Naito A, Yoshida H, Nishioka E, Satoh M, Azuma S, Yamamoto T, Nishikawa S, Inoue J, TRAF6-deficient mice display hypohidrotic ectodermal dysplasia. Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8766-71
10*	J:78842 Nishioka E, Tanaka T, Yoshida H, Matsumura K, Nishikawa S, Naito A, Inoue J, Funasaka Y, Ichihashi M, Miyasaka M, Nishikawa S, Mucosal addressin cell adhesion molecule 1 plays an unexpected role in the development of mouse guard hair. J Invest Dermatol. 2002 Sep;119(3):632-8
3	J:259045 Onder L, Morbe U, Pikor N, Novkovic M, Cheng HW, Hehlgans T, Pfeffer K, Becher B, Waisman A, Rulicke T, Gommerman J, Mueller CG, Sawa S, Scandella E, Ludewig B, Lymphatic Endothelial Cells Control Initiation of Lymph Node Organogenesis. Immunity. 2017 Jul 18;47(1):80-92.e4
1	J:305472 Prados A, Onder L, Cheng HW, Morbe U, Lutge M, Gil-Cruz C, Perez-Shibayama C, Koliaraki V, Ludewig B, Kollias G, Fibroblastic reticular cell lineage convergence in Peyer's patches governs intestinal immunity. Nat Immunol. 2021 Apr;22(4):510-519
1	J:239420 Rantakari P, Jappinen N, Lokka E, Mokkala E, Gerke H, Peuhu E, Ivaska J, Elima K, Auvinen K, Salmi M, Fetal liver endothelium regulates the seeding of tissue-resident macrophages. Nature. 2016 Oct 20;538(7625):392-396
2	J:160065 Reijmers RM, Vondenhoff MF, Roozendaal R, Kuil A, Li JP, Spaargaren M, Pals ST, Mebius RE, Impaired lymphoid organ development in mice lacking the heparan sulfate modifying enzyme glucuronyl C5-epimerase. J Immunol. 2010 Apr 1;184(7):3656-64
4	J:338451 Shintani A, Fukai S, Nobusawa R, Taniguchi K, Hatatani T, Nagai H, Sakai T, Yoshimura T, Miyasaka M, Hayasaka H, Dach1 transcription factor regulates the expression of peripheral node addressin and lymphocyte trafficking in lymph nodes. Curr Res Immunol. 2022;3:175-185
1*	J:244896 Stachtea XN, Tykesson E, van Kuppevelt TH, Feinstein R, Malmstrom A, Reijmers RM, Maccarana M, Dermatan Sulfate-Free Mice Display Embryological Defects and Are Neonatal Lethal Despite Normal Lymphoid and Non-Lymphoid Organogenesis. PLoS One. 2015;10(10):e0140279
1*	J:184087 Sugiyama M, Nakato G, Jinnohara T, Akiba H, Okumura K, Ohno H, Yoshida H, Expression pattern changes and function of RANKL during mouse lymph node microarchitecture development. Int Immunol. 2012 Jun;24(6):369-78
1*	J:338194 Sulic AM, Das Roy R, Papagno V, Lan Q, Saikkonen R, Jernvall J, Thesleff I, Mikkola ML, Transcriptomic landscape of early hair follicle and epidermal development. Cell Rep. 2023 Jun 13;42(6):112643
1	J:235538 Tomann P, Paus R, Millar SE, Scheidereit C, Schmidt-Ullrich R, Lhx2 is a direct NF-kappaB target gene that promotes primary hair follicle placode down-growth. Development. 2016 May 1;143(9):1512-22
3	J:157747 van de Pavert SA, Olivier BJ, Goverse G, Vondenhoff MF, Greuter M, Beke P, Kusser K, Hopken UE, Lipp M, Niederreither K, Blomhoff R, Sitnik K, Agace WW, Randall TD, de Jonge WJ, Mebius RE, Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation. Nat Immunol. 2009 Nov;10(11):1193-9
3	J:137812 Vondenhoff MF, Desanti GE, Cupedo T, Bertrand JY, Cumano A, Kraal G, Mebius RE, Golub R, Separation of splenic red and white pulp occurs before birth in a LTalphabeta-independent manner. J Leukoc Biol. 2008 Jul;84(1):152-61
3	J:150308 Vondenhoff MF, Greuter M, Goverse G, Elewaut D, Dewint P, Ware CF, Hoorweg K, Kraal G, Mebius RE, LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen. J Immunol. 2009 May 1;182(9):5439-45
3	J:142686 Vondenhoff MF, van de Pavert SA, Dillard ME, Greuter M, Goverse G, Oliver G, Mebius RE, Lymph sacs are not required for the initiation of lymph node formation. Development. 2009 Jan;136(1):29-34
1*	J:231699 Voutilainen M, Lindfors PH, Trela E, Lonnblad D, Shirokova V, Elo T, Rysti E, Schmidt-Ullrich R, Schneider P, Mikkola ML, Ectodysplasin/NF-kappaB Promotes Mammary Cell Fate via Wnt/beta-catenin Pathway. PLoS Genet. 2015 Nov;11(11):e1005676
5	J:64018 Wang CC, Biben C, Robb L, Nassir F, Barnett L, Davidson NO, Koentgen F, Tarlinton D, Harvey RP, Homeodomain factor Nkx2-3 controls regional expression of leukocyte homing coreceptor MAdCAM-1 in specialized endothelial cells of the viscera. Dev Biol. 2000 Aug 15;224(2):152-67
1	J:263332 Wang Z, Chai Q, Zhu M, Differential Roles of LTbetaR in Endothelial Cell Subsets for Lymph Node Organogenesis and Maturation. J Immunol. 2018 Jul 1;201(1):69-76