Gene Expression Literature Summary
|
Symbol Name ID |
Bmp7
bone morphogenetic protein 7 MGI:103302 |
| Age | E6 | E6.5 | E7 | E7.5 | E8 | E8.5 | E9 | E9.5 | E10 | E10.5 | E11 | E11.5 | E12 | E12.5 | E13 | E13.5 | E14 | E14.5 | E15 | E15.5 | E16 | E16.5 | E17 | E17.5 | E18 | E18.5 | E19 | E19.5 | E | P |
| Immunohistochemistry (section) | 1 | 1 | 1 | 2 | 1 | 1 | 4 | 1 | 1 | 2 | 3 | 3 | 1 | 1 | 1 | 3 | 1 | 1 | 1 | 5 | ||||||||||
| In situ RNA (section) | 1 | 1 | 4 | 5 | 8 | 8 | 22 | 3 | 34 | 3 | 18 | 3 | 39 | 6 | 25 | 4 | 39 | 3 | 20 | 1 | 23 | 1 | 7 | 2 | 6 | 1 | 2 | 12 | 18 | |
| Immunohistochemistry (whole mount) | 1 | 1 | 1 | 1 | 1 | |||||||||||||||||||||||||
| In situ RNA (whole mount) | 2 | 4 | 4 | 7 | 11 | 9 | 17 | 2 | 24 | 7 | 21 | 2 | 31 | 1 | 25 | 1 | 5 | 4 | 1 | 2 | 2 | 7 | 1 | |||||||
| In situ reporter (knock in) | 1 | 1 | 4 | 3 | 2 | 1 | 7 | 1 | 10 | 1 | 8 | 7 | 3 | 1 | 4 | 3 | 1 | 2 | 4 | |||||||||||
| Northern blot | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 4 | ||||||||||||||||||||
| Western blot | 1 | 1 | 1 | 2 | 3 | 1 | 1 | 1 | 1 | 1 | 1 | 4 | ||||||||||||||||||
| RT-PCR | 1 | 2 | 5 | 9 | 1 | 9 | 4 | 12 | 4 | 8 | 3 | 16 | 1 | 6 | 3 | 8 | 3 | 5 | 1 | 11 | 1 | 2 | 23 | |||||||
| cDNA clones | 2 | 1 | 1 | 2 | 2 | 2 | ||||||||||||||||||||||||
| RNase protection | 1 | 1 |
| Bmp7 bone morphogenetic protein 7 (Synonyms: OP1, osteogenic protein 1) | |
| Results | Reference |
| 12 | J:44411 Aberg T, Wozney J, Thesleff I, Expression patterns of bone morphogenetic proteins (Bmps) in the developing mouse tooth suggest roles in morphogenesis and cell differentiation. Dev Dyn. 1997 Dec;210(4):383-96 |
| 2 | J:63377 Abidari JM, Gonzales ET, Inoue K, Lupski JR, Karsenty G, Katsanis N, Identification of novel genes expressed during metanephric induction through single-cell library screening. Kidney Int. 2000 Jun;57(6):2221-8 |
| 9* | J:127521 Adams D, Karolak M, Robertson E, Oxburgh L, Control of kidney, eye and limb expression of Bmp7 by an enhancer element highly conserved between species. Dev Biol. 2007 Nov 15;311(2):679-90 |
| 1 | J:73526 Ahn K, Mishina Y, Hanks MC, Behringer RR, Crenshaw EB 3rd, BMPR-IA signaling is required for the formation of the apical ectodermal ridge and dorsal-ventral patterning of the limb. Development. 2001 Nov;128(22):4449-61 |
| 2 | J:315767 Ahn SY, Kim Y, Kim ST, Swat W, Miner JH, Scaffolding proteins DLG1 and CASK cooperate to maintain the nephron progenitor population during kidney development. J Am Soc Nephrol. 2013 Jun;24(7):1127-38 |
| 2* | J:184022 Aizawa R, Yamada A, Suzuki D, Iimura T, Kassai H, Harada T, Tsukasaki M, Yamamoto G, Tachikawa T, Nakao K, Yamamoto M, Yamaguchi A, Aiba A, Kamijo R, Cdc42 is required for chondrogenesis and interdigital programmed cell death during limb development. Mech Dev. 2012 Mar;129(1-4):38-50 |
| 3* | J:75699 Albrecht AN, Schwabe GC, Stricker S, Boddrich A, Wanker EE, Mundlos S, The synpolydactyly homolog (spdh) mutation in the mouse -- a defect in patterning and growth of limb cartilage elements. Mech Dev. 2002 Mar;112(1-2):53-67 |
| 1 | J:240005 Aldiri I, Ajioka I, Xu B, Zhang J, Chen X, Benavente C, Finkelstein D, Johnson D, Akiyama J, Pennacchio LA, Dyer MA, Brg1 coordinates multiple processes during retinogenesis and is a tumor suppressor in retinoblastoma. Development. 2015 Dec 01;142(23):4092-106 |
| 2 | J:232560 Anderson MJ, Schimmang T, Lewandoski M, An FGF3-BMP Signaling Axis Regulates Caudal Neural Tube Closure, Neural Crest Specification and Anterior-Posterior Axis Extension. PLoS Genet. 2016 May;12(5):e1006018 |
| 1* | J:79855 Anderson RM, Lawrence AR, Stottmann RW, Bachiller D, Klingensmith J, Chordin and noggin promote organizing centers of forebrain development in the mouse. Development. 2002 Nov;129(21):4975-87 |
| 3 | J:76477 Andl T, Reddy ST, Gaddapara T, Millar SE, WNT Signals Are Required for the Initiation of Hair Follicle Development. Dev Cell. 2002 May;2(5):643-53 |
| 11* | J:38384 Arkell R, Beddington RS, BMP-7 influences pattern and growth of the developing hindbrain of mouse embryos. Development. 1997 Jan;124(1):1-12 |
| 5 | J:199300 Bai Y, Wang J, Morikawa Y, Bonilla-Claudio M, Klysik E, Martin JF, Bmp signaling represses Vegfa to promote outflow tract cushion development. Development. 2013 Aug;140(16):3395-402 |
| 1 | J:118257 Bandyopadhyay A, Tsuji K, Cox K, Harfe BD, Rosen V, Tabin CJ, Genetic Analysis of the Roles of BMP2, BMP4, and BMP7 in Limb Patterning and Skeletogenesis. PLoS Genet. 2006 Dec 22;2(12):e216 |
| 3 | J:62547 Barna M, Hawe N, Niswander L, Pandolfi PP, Plzf regulates limb and axial skeletal patterning. Nat Genet. 2000 Jun;25(2):166-72 |
| 1 | J:131764 Basson MA, Echevarria D, Petersen Ahn C, Sudarov A, Joyner AL, Mason IJ, Martinez S, Martin GR, Specific regions within the embryonic midbrain and cerebellum require different levels of FGF signaling during development. Development. 2008 Mar;135(5):889-98 |
| 4 | J:208419 Basta JM, Robbins L, Kiefer SM, Dorsett D, Rauchman M, Sall1 balances self-renewal and differentiation of renal progenitor cells. Development. 2014 Mar;141(5):1047-58 |
| 1* | J:293793 Basta JM, Singh AP, Robbins L, Stout L, Pherson M, Rauchman M, The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Dev Biol. 2020 Aug 15;464(2):176-187 |
| 1* | J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034 |
| 4 | J:149988 Beites CL, Hollenbeck PL, Kim J, Lovell-Badge R, Lander AD, Calof AL, Follistatin modulates a BMP autoregulatory loop to control the size and patterning of sensory domains in the developing tongue. Development. 2009 Jul;136(13):2187-97 |
| 2* | J:33591 Bellusci S, Henderson R, Winnier G, Oikawa T, Hogan BL, Evidence from normal expression and targeted misexpression that bone morphogenetic protein (Bmp-4) plays a role in mouse embryonic lung morphogenesis. Development. 1996 Jun;122(6):1693-702 |
| 2 | J:144933 Benazet JD, Bischofberger M, Tiecke E, Goncalves A, Martin JF, Zuniga A, Naef F, Zeller R, A self-regulatory system of interlinked signaling feedback loops controls mouse limb patterning. Science. 2009 Feb 20;323(5917):1050-3 |
| 2 | J:189073 Benazet JD, Pignatti E, Nugent A, Unal E, Laurent F, Zeller R, Smad4 is required to induce digit ray primordia and to initiate the aggregation and differentiation of chondrogenic progenitors in mouse limb buds. Development. 2012 Nov;139(22):4250-60 |
| 2 | J:171190 Bensoussan-Trigano V, Lallemand Y, Saint Cloment C, Robert B, Msx1 and Msx2 in limb mesenchyme modulate digit number and identity. Dev Dyn. 2011 May;240(5):1190-202 |
| 4* | J:93300 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL, Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247 |
| 2* | J:278801 Bloomquist RF, Fowler TE, An Z, Yu TY, Abdilleh K, Fraser GJ, Sharpe PT, Streelman JT, Developmental plasticity of epithelial stem cells in tooth and taste bud renewal. Proc Natl Acad Sci U S A. 2019 Sep 3;116(36):17858-17866 |
| 1 | J:117635 Bose K, Nischt R, Page A, Bader BL, Paulsson M, Smyth N, Loss of nidogen-1 and -2 results in syndactyly and changes in limb development. J Biol Chem. 2006 Dec 22;281(51):39620-9 |
| 1* | J:67304 Bulchand S, Grove EA, Porter FD, Tole S, LIM-homeodomain gene Lhx2 regulates the formation of the cortical hem. Mech Dev. 2001 Feb;100(2):165-75 |
| 1 | J:83462 Butler SJ, Dodd J, A role for BMP heterodimers in roof plate-mediated repulsion of commissural axons. Neuron. 2003 May 8;38(3):389-401 |
| 1 | J:153595 Butterfield NC, Metzis V, McGlinn E, Bruce SJ, Wainwright BJ, Wicking C, Patched 1 is a crucial determinant of asymmetry and digit number in the vertebrate limb. Development. 2009 Oct;136(20):3515-24 |
| 3 | J:95093 Cai CL, Liang X, Shi Y, Chu PH, Pfaff SL, Chen J, Evans S, Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart. Dev Cell. 2003 Dec;5(6):877-89 |
| 1 | J:98516 Cai CL, Zhou W, Yang L, Bu L, Qyang Y, Zhang X, Li X, Rosenfeld MG, Chen J, Evans S, T-box genes coordinate regional rates of proliferation and regional specification during cardiogenesis. Development. 2005 May;132(10):2475-87 |
| 1 | J:178530 Cai X, Nomura-Kitabayashi A, Cai W, Yan J, Christoffels VM, Cai CL, Myocardial Tbx20 regulates early atrioventricular canal formation and endocardial epithelial-mesenchymal transition via Bmp2. Dev Biol. 2011 Dec 15;360(2):381-90 |
| 1 | J:198655 Cai Z, Tao C, Li H, Ladher R, Gotoh N, Feng GS, Wang F, Zhang X, Deficient FGF signaling causes optic nerve dysgenesis and ocular coloboma. Development. 2013 Jul;140(13):2711-23 |
| 1 | J:226411 Caprioli A, Villasenor A, Wylie LA, Braitsch C, Marty-Santos L, Barry D, Karner CM, Fu S, Meadows SM, Carroll TJ, Cleaver O, Wnt4 is essential to normal mammalian lung development. Dev Biol. 2015 Oct 15;406(2):222-34 |
| 1 | J:209730 Cardelli M, Zirngibl RA, Boetto JF, McKenzie KP, Troy TC, Turksen K, Aubin JE, Cartilage-specific overexpression of ERRgamma results in Chondrodysplasia and reduced chondrocyte proliferation. PLoS One. 2013;8(12):e81511 |
| 2 | J:100575 Carroll TJ, Park JS, Hayashi S, Majumdar A, McMahon AP, Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system. Dev Cell. 2005 Aug;9(2):283-92 |
| 2* | J:112220 Caruana G, Cullen-McEwen L, Nelson AL, Kostoulias X, Woods K, Gardiner B, Davis MJ, Taylor DF, Teasdale RD, Grimmond SM, Little MH, Bertram JF, Spatial gene expression in the T-stage mouse metanephros. Gene Expr Patterns. 2006 Dec;6(8):807-25 |
| 1 | J:170491 Casanova JC, Uribe V, Badia-Careaga C, Giovinazzo G, Torres M, Sanz-Ezquerro JJ, Apical ectodermal ridge morphogenesis in limb development is controlled by Arid3b-mediated regulation of cell movements. Development. 2011 Mar;138(6):1195-205 |
| 2 | J:199615 Cases O, Perea-Gomez A, Aguiar DP, Nykjaer A, Amsellem S, Chandellier J, Umbhauer M, Cereghini S, Madsen M, Collignon J, Verroust P, Riou JF, Creuzet SE, Kozyraki R, Cubilin, a high affinity receptor for fibroblast growth factor 8, is required for cell survival in the developing vertebrate head. J Biol Chem. 2013 Jun 7;288(23):16655-70 |
| 3* | J:94934 Challen GA, Martinez G, Davis MJ, Taylor DF, Crowe M, Teasdale RD, Grimmond SM, Little MH, Identifying the molecular phenotype of renal progenitor cells. J Am Soc Nephrol. 2004 Sep;15(9):2344-57 |
| 3* | J:316102 Chen T, Wu Q, Zhang Y, Lu T, Yue W, Zhang D, Tcf4 Controls Neuronal Migration of the Cerebral Cortex through Regulation of Bmp7. Front Mol Neurosci. 2016;9:94 |
| 1 | J:274818 Chen Y, Wang Z, Chen Y, Zhang Y, Conditional deletion of Bmp2 in cranial neural crest cells recapitulates Pierre Robin sequence in mice. Cell Tissue Res. 2019 May;376(2):199-210 |
| 1 | J:138713 Cho A, Ko HW, Eggenschwiler JT, FKBP8 cell-autonomously controls neural tube patterning through a Gli2- and Kif3a-dependent mechanism. Dev Biol. 2008 Sep 1;321(1):27-39 |
| 2 | J:217413 Choe Y, Huynh T, Pleasure SJ, Migration of oligodendrocyte progenitor cells is controlled by transforming growth factor beta family proteins during corticogenesis. J Neurosci. 2014 Nov 5;34(45):14973-83 |
| 3 | J:196652 Choe Y, Kozlova A, Graf D, Pleasure SJ, Bone morphogenic protein signaling is a major determinant of dentate development. J Neurosci. 2013 Apr 17;33(16):6766-75 |
| 3 | J:182705 Choe Y, Siegenthaler JA, Pleasure SJ, A cascade of morphogenic signaling initiated by the meninges controls corpus callosum formation. Neuron. 2012 Feb 23;73(4):698-712 |
| 3 | J:221100 Choi KS, Lee C, Maatouk DM, Harfe BD, Bmp2, Bmp4 and Bmp7 are co-required in the mouse AER for normal digit patterning but not limb outgrowth. PLoS One. 2012;7(5):e37826 |
| 1 | J:154611 Chou SJ, Perez-Garcia CG, Kroll TT, O'Leary DD, Lhx2 specifies regional fate in Emx1 lineage of telencephalic progenitors generating cerebral cortex. Nat Neurosci. 2009 Nov;12(11):1381-9 |
| 1* | J:203431 Collette NM, Yee CS, Murugesh D, Sebastian A, Taher L, Gale NW, Economides AN, Harland RM, Loots GG, Sost and its paralog Sostdc1 coordinate digit number in a Gli3-dependent manner. Dev Biol. 2013 Nov 1;383(1):90-105 |
| 2* | J:34068 Constam DB, Calfon M, Robertson EJ, SPC4, SPC6, and the novel protease SPC7 are coexpressed with bone morphogenetic proteins at distinct sites during embryogenesis. J Cell Biol. 1996 Jul;134(1):181-91 |
| 1* | J:51599 Coucouvanis E, Martin GR, BMP signaling plays a role in visceral endoderm differentiation and cavitation in the early mouse embryo. Development. 1999 Feb;126(3):535-46 |
| 1 | J:103334 Cui YZ, Peng YF, Tian Q, Expression of man, a formin homology domain-containing gene in the mouse limb. Sheng Li Xue Bao. 2005 Aug 25;57(4):433-438 |
| 1* | J:100435 Currle DS, Cheng X, Hsu CM, Monuki ES, Direct and indirect roles of CNS dorsal midline cells in choroid plexus epithelia formation. Development. 2005 Aug;132(15):3549-59 |
| 1 | J:169302 da Silva S, Hasegawa H, Scott A, Zhou X, Wagner AK, Han BX, Wang F, Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-{beta} signaling. Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3395-400 |
| 8* | J:148775 Danesh SM, Villasenor A, Chong D, Soukup C, Cleaver O, BMP and BMP receptor expression during murine organogenesis. Gene Expr Patterns. 2009 Jun;9(5):255-65 |
| 1 | J:335592 de Lope C, Garcia-Lucena R, Magarinos M, Leon Y, Casa-Rodriguez N, Contreras N, Escudero-Iriarte C, Varela-Nieto I, Maire P, Palmero I, Dysfunction of programmed embryo senescence is linked to genetic developmental defects. Development. 2023 May 1;150(9):dev200903 |
| 3 | J:156972 De Rosa L, Antonini D, Ferone G, Russo MT, Yu PB, Han R, Missero C, p63 Suppresses non-epidermal lineage markers in a bone morphogenetic protein-dependent manner via repression of Smad7. J Biol Chem. 2009 Oct 30;284(44):30574-82 |
| 8 | J:92055 Dean C, Ito M, Makarenkova HP, Faber SC, Lang RA, Bmp7 regulates branching morphogenesis of the lacrimal gland by promoting mesenchymal proliferation and condensation. Development. 2004 Sep;131(17):4155-65 |
| 1 | J:132122 Delgado I, Dominguez-Frutos E, Schimmang T, Ros MA, The incomplete inactivation of Fgf8 in the limb ectoderm affects the morphogenesis of the anterior autopod through BMP-mediated cell death. Dev Dyn. 2008 Mar;237(3):649-58 |
| 1 | J:79553 Depew MJ, Lufkin T, Rubenstein JL, Specification of jaw subdivisions by Dlx genes. Science. 2002 Oct 11;298(5592):381-5 |
| 1 | J:108241 Desai J, Shannon ME, Johnson MD, Ruff DW, Hughes LA, Kerley MK, Carpenter DA, Johnson DK, Rinchik EM, Culiat CT, Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects. Hum Mol Genet. 2006 Apr 15;15(8):1329-41 |
| 4 | J:221164 Di Giovanni V, Walker KA, Bushnell D, Schaefer C, Sims-Lucas S, Puri P, Bates CM, Fibroblast growth factor receptor-Frs2alpha signaling is critical for nephron progenitors. Dev Biol. 2015 Apr 1;400(1):82-93 |
| 7* | J:82773 Dichmann DS, Miller CP, Jensen J, Scott Heller R, Serup P, Expression and misexpression of members of the FGF and TGFbeta families of growth factors in the developing mouse pancreas. Dev Dyn. 2003 Apr;226(4):663-74 |
| 9 | J:164103 Du Y, Xiao Q, Yip HK, Regulation of retinal progenitor cell differentiation by bone morphogenetic protein 4 is mediated by the smad/id cascade. Invest Ophthalmol Vis Sci. 2010 Jul;51(7):3764-73 |
| 5 | J:30057 Dudley AT, Lyons KM, Robertson EJ, A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye. Genes Dev. 1995 NOV 15;9(22):2795-2807 |
| 7* | J:39018 Dudley AT, Robertson EJ, Overlapping expression domains of bone morphogenetic protein family members potentially account for limited tissue defects in BMP7 deficient embryos. Dev Dyn. 1997 Mar;208(3):349-62 |
| 1 | J:162165 Dudley B, Palumbo C, Nalepka J, Molyneaux K, BMP signaling controls formation of a primordial germ cell niche within the early genital ridges. Dev Biol. 2010 Jul 1;343(1-2):84-93 |
| 2* | J:54066 Dupe V, Ghyselinck NB, Thomazy V, Nagy L, Davies PJA, Chambon P, Mark M, Essential roles of retinoic acid signaling in interdigital apoptosis and control of BMP-7 expression in mouse autopods. Dev Biol. 1999 Apr 1;208(1):30-43 |
| 1 | J:65763 Eggenschwiler JT, Anderson KV, Dorsal and lateral fates in the mouse neural tube require the cell-autonomous activity of the open brain gene. Dev Biol. 2000 Nov 15;227(2):648-60 |
| 2* | J:86841 Elms P, Siggers P, Napper D, Greenfield A, Arkell R, Zic2 is required for neural crest formation and hindbrain patterning during mouse development. Dev Biol. 2003 Dec 15;264(2):391-406 |
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| 3 | J:272386 Fan X, Wang D, Burgmaier JE, Teng Y, Romano RA, Sinha S, Yi R, Single Cell and Open Chromatin Analysis Reveals Molecular Origin of Epidermal Cells of the Skin. Dev Cell. 2018 Oct 8;47(1):21-37.e5 |
| 2 | J:213659 Fausett SR, Brunet LJ, Klingensmith J, BMP antagonism by Noggin is required in presumptive notochord cells for mammalian foregut morphogenesis. Dev Biol. 2014 Jul 1;391(1):111-24 |
| 3 | J:49552 Ferguson CA, Tucker AS, Christensen L, Lau AL, Matzuk MM, Sharpe PT, Activin is an essential early mesenchymal signal in tooth development that is required for patterning of the murine dentition. Genes Dev. 1998 Aug 15;12(16):2636-49 |
| 1 | J:192165 Forsman CL, Ng BC, Heinze RK, Kuo C, Sergi C, Gopalakrishnan R, Yee D, Graf D, Schwertfeger KL, Petryk A, BMP-binding protein twisted gastrulation is required in mammary gland epithelium for normal ductal elongation and myoepithelial compartmentalization. Dev Biol. 2013 Jan 1;373(1):95-106 |
| 2* | J:255607 Fu X, Xu J, Chaturvedi P, Liu H, Jiang R, Lan Y, Identification of Osr2 Transcriptional Target Genes in Palate Development. J Dent Res. 2017 Nov;96(12):1451-1458 |
| 3 | J:166947 Fujimori S, Novak H, Weissenbock M, Jussila M, Goncalves A, Zeller R, Galloway J, Thesleff I, Hartmann C, Wnt/beta-catenin signaling in the dental mesenchyme regulates incisor development by regulating Bmp4. Dev Biol. 2010 Dec 1;348(1):97-106 |
| 2 | J:140928 Furtado MB, Solloway MJ, Jones VJ, Costa MW, Biben C, Wolstein O, Preis JI, Sparrow DB, Saga Y, Dunwoodie SL, Robertson EJ, Tam PP, Harvey RP, BMP/SMAD1 signaling sets a threshold for the left/right pathway in lateral plate mesoderm and limits availability of SMAD4. Genes Dev. 2008 Nov 1;22(21):3037-49 |
| 1* | J:51570 Furuta Y, Hogan BLM, BMP4 is essential for lens induction in the mouse embryo. Genes Dev. 1998 Dec 1;12(23):3764-75 |
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| 6 | J:157308 Gai Z, Zhou G, Itoh S, Morimoto Y, Tanishima H, Hatamura I, Uetani K, Ito M, Muragaki Y, Trps1 functions downstream of Bmp7 in kidney development. J Am Soc Nephrol. 2009 Nov;20(11):2403-11 |
| 1 | J:264602 Gamer LW, Pregizer S, Gamer J, Feigenson M, Ionescu A, Li Q, Han L, Rosen V, The Role of Bmp2 in the Maturation and Maintenance of the Murine Knee Joint. J Bone Miner Res. 2018 Sep;33(9):1708-1717 |
| 2 | J:191791 Garrido-Allepuz C, Gonzalez-Lamuno D, Ros MA, Sirenomelia phenotype in bmp7;shh compound mutants: a novel experimental model for studies of caudal body malformations. PLoS One. 2012;7(9):e44962 |
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| 2 | J:172359 Goncalves A, Zeller R, Genetic Analysis Reveals an Unexpected Role of BMP7 in Initiation of Ureteric Bud Outgrowth in Mouse Embryos. PLoS One. 2011;6(4):e19370 |
| 2 | J:280117 Gong X, Guo X, Huang R, Liao H, Zhang Q, Yan J, Luo L, Zhang Q, Qiu A, Sun Y, Liang X, Expression of ILK in renal stroma is essential for multiple aspects of renal development. Am J Physiol Renal Physiol. 2018 Aug 1;315(2):F374-F385 |
| 3* | J:233000 Gornikiewicz B, Ronowicz A, Krzeminski M, Sachadyn P, Changes in gene methylation patterns in neonatal murine hearts: Implications for the regenerative potential. BMC Genomics. 2016;17:231 |
| 6 | J:104840 Grishina IB, Kim SY, Ferrara C, Makarenkova HP, Walden PD, BMP7 inhibits branching morphogenesis in the prostate gland and interferes with Notch signaling. Dev Biol. 2005 Dec 15;288(2):334-47 |
| 1 | J:80081 Gritli-Linde A, Bei M, Maas R, Zhang XM, Linde A, McMahon AP, Shh signaling within the dental epithelium is necessary for cell proliferation, growth and polarization. Development. 2002 Dec;129(23):5323-37 |
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| 2* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
| 1 | J:176341 Hagglund AC, Dahl L, Carlsson L, Lhx2 is required for patterning and expansion of a distinct progenitor cell population committed to eye development. PLoS One. 2011;6(8):e23387 |
| 1 | J:239666 Hagglund AC, Jones I, Carlsson L, A novel mouse model of anterior segment dysgenesis (ASD): conditional deletion of Tsc1 disrupts ciliary body and iris development. Dis Model Mech. 2017 Mar 01;10(3):245-257 |
| 2* | J:125119 Han J, Ishii M, Bringas P Jr, Maas RL, Maxson RE Jr, Chai Y, Concerted action of Msx1 and Msx2 in regulating cranial neural crest cell differentiation during frontal bone development. Mech Dev. 2007 Sep-Oct;124(9-10):729-45 |
| 1 | J:100475 Harfe BD, McManus MT, Mansfield JH, Hornstein E, Tabin CJ, The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb. Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):10898-903 |
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| 6 | J:47864 Helder MN, Karg H, Bervoets TJ, Vukicevic S, Burger EH, D'Souza RN, Woltgens JH, Karsenty G, Bronckers AL, Bone morphogenetic protein-7 (osteogenic protein-1, OP-1) and tooth development. J Dent Res. 1998 Apr;77(4):545-54 |
| 5* | J:28796 Helder MN, Ozkaynak E, Sampath KT, Luyten FP, Latin V, Oppermann H, Vukicevic S, Expression pattern of osteogenic protein-1 (bone morphogenetic protein-7) in human and mouse development. J Histochem Cytochem. 1995 Oct;43(10):1035-44 |
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| 5 | J:53380 Wawersik S, Purcell P, Rauchman M, Dudley AT, Robertson EJ, Maas R, BMP7 acts in murine lens placode development. Dev Biol. 1999 Mar 1;207(1):176-88 |
| 3 | J:300975 Weiss AC, Rivera-Reyes R, Englert C, Kispert A, Expansion of the renal capsular stroma, ureteric bud branching defects and cryptorchidism in mice with Wilms tumor 1 gene deletion in the stromal compartment of the developing kidney. J Pathol. 2020 Nov;252(3):290-303 |
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| 1 | J:149459 Wuelling M, Kaiser FJ, Buelens LA, Braunholz D, Shivdasani RA, Depping R, Vortkamp A, Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3. Dev Biol. 2009 Apr 1;328(1):40-53 |
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| 1 | J:187117 Xu J, Qi X, Gong J, Yu M, Zhang F, Sha H, Gao X, Fstl1 antagonizes BMP signaling and regulates ureter development. PLoS One. 2012;7(4):e32554 |
| 1 | J:184324 Xu K, Wu X, Shapiro E, Huang H, Zhang L, Hickling D, Deng Y, Lee P, Li J, Lepor H, Grishina I, Bmp7 functions via a polarity mechanism to promote cloacal septation. PLoS One. 2012;7(1):e29372 |
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| 1 | J:161524 Yang YP, Anderson RM, Klingensmith J, BMP antagonism protects Nodal signaling in the gastrula to promote the tissue interactions underlying mammalian forebrain and craniofacial patterning. Hum Mol Genet. 2010 Aug 1;19(15):3030-42 |
| 1* | J:166958 Yates LL, Papakrivopoulou J, Long DA, Goggolidou P, Connolly JO, Woolf AS, Dean CH, The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation. Hum Mol Genet. 2010 Dec 1;19(23):4663-76 |
| 2 | J:124256 Ybot-Gonzalez P, Gaston-Massuet C, Girdler G, Klingensmith J, Arkell R, Greene ND, Copp AJ, Neural plate morphogenesis during mouse neurulation is regulated by antagonism of Bmp signalling. Development. 2007 Sep;134(17):3203-11 |
| 6* | J:164472 Yi T, Tan K, Cho SG, Wang Y, Luo J, Zhang W, Li D, Liu M, Regulation of embryonic kidney branching morphogenesis and glomerular development by KISS1 receptor (Gpr54) through NFAT2- and Sp1-mediated Bmp7 expression. J Biol Chem. 2010 Jun 4;285(23):17811-20 |
| 2 | J:154982 Yun S, Saijoh Y, Hirokawa KE, Kopinke D, Murtaugh LC, Monuki ES, Levine EM, Lhx2 links the intrinsic and extrinsic factors that control optic cup formation. Development. 2009 Dec;136(23):3895-906 |
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| 1 | J:173972 Zhao H, Li S, Han D, Kaartinen V, Chai Y, Alk5-mediated transforming growth factor beta signaling acts upstream of fibroblast growth factor 10 to regulate the proliferation and maintenance of dental epithelial stem cells. Mol Cell Biol. 2011 May;31(10):2079-89 |
| 1 | J:182725 Zhao L, Zevallos SE, Rizzoti K, Jeong Y, Lovell-Badge R, Epstein DJ, Disruption of SoxB1-dependent Sonic hedgehog expression in the hypothalamus causes septo-optic dysplasia. Dev Cell. 2012 Mar 13;22(3):585-96 |
| 1 | J:78682 Zhao S, Chen Q, Hung FC, Overbeek PA, BMP signaling is required for development of the ciliary body. Development. 2002 Oct;129(19):4435-42 |
| 1 | J:156950 Zhao X, Brade T, Cunningham TJ, Duester G, Retinoic acid controls expression of tissue remodeling genes Hmgn1 and Fgf18 at the digit-interdigit junction. Dev Dyn. 2010 Feb;239(2):665-71 |
| 1* | J:66280 Zhao X, Zhang Z, Song Y, Zhang X, Zhang Y, Hu Y, Fromm SH, Chen Y, Transgenically ectopic expression of bmp4 to the msx1 mutant dental mesenchyme restores downstream gene expression but represses shh and bmp2 in the enamel knot of wild type tooth germ. Mech Dev. 2000 Dec;99(1-2):29-38 |
| 1 | J:55103 Zhao Y, Sheng HZ, Amini R, Grinberg A, Lee E, Huang S, Taira M, Westphal H, Control of hippocampal morphogenesis and neuronal differentiation by the LIM homeobox gene Lhx5. Science. 1999 May 14;284(5417):1155-8 |
| 2 | J:315014 Zhou C, Chen D, Ren J, Huang D, Li R, Luo H, Guan C, Cao Y, Wang W, FGF8 and BMP2 mediated dynamic regulation of dental mesenchyme proliferation and differentiation via Lhx8/Suv39h1 complex. J Cell Mol Med. 2021 Mar;25(6):3051-3062 |
| 1 | J:316215 Zhou N, Li N, Liu J, Wang Y, Gao J, Wu Y, Chen X, Liu C, Xiao J, Persistent Wnt/beta-catenin signaling in mouse epithelium induces the ectopic Dspp expression in cheek mesenchyme. Organogenesis. 2019;15(1):1-12 |
| 3 | J:278474 Zhu XJ, Liu Y, Dai ZM, Zhang X, Yang X, Li Y, Qiu M, Fu J, Hsu W, Chen Y, Zhang Z, BMP-FGF signaling axis mediates Wnt-induced epidermal stratification in developing mammalian skin. PLoS Genet. 2014 Oct;10(10):e1004687 |
| 1 | J:94396 Zou D, Silvius D, Fritzsch B, Xu PX, Eya1 and Six1 are essential for early steps of sensory neurogenesis in mammalian cranial placodes. Development. 2004 Nov;131(22):5561-72 |
| 10 | J:148972 Zouvelou V, Luder HU, Mitsiadis TA, Graf D, Deletion of BMP7 affects the development of bones, teeth, and other ectodermal appendages of the orofacial complex. J Exp Zoolog B Mol Dev Evol. 2009 Jan 6;312B(4):361-374 |
| 2 | J:149134 Zouvelou V, Passa O, Segklia K, Tsalavos S, Valenzuela DM, Economides AN, Graf D, Generation and functional characterization of mice with a conditional BMP7 allele. Int J Dev Biol. 2009;53(4):597-603 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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