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Gene Expression Literature Summary
Symbol
Name
ID
Itga7
integrin alpha 7
MGI:102700

39 matching records from 39 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E3.5 E4 E4.5 E5 E5.5 E6.5 E7.5 E8.5 E9 E9.5 E10 E10.5 E11 E11.5 E12 E12.5 E13 E13.5 E14 E14.5 E15 E15.5 E16 E16.5 E17 E17.5 E18 E18.5 E P
Immunohistochemistry (section) 2 1 1 1 2 1 2 2 1 2 1 1 2 1 1 1 3 1 3 13
In situ RNA (section) 1 1 1 1 1 1 1 1 1 1 1 2
Immunohistochemistry (whole mount) 1 1 1 1
In situ reporter (knock in) 1 1 1 1 1 2 1
Northern blot 1 1
Western blot 1 1 1 1 1 1 1 4
RT-PCR 3 3 2 1 1 1 1 1 1 1 1 1 7

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Itga7  integrin alpha 7   (Synonyms: [a]7, alpha7)
Results  Reference
4*J:93087 Bajanca F, Luz M, Duxson MJ, Thorsteinsdottir S, Integrins in the mouse myotome: developmental changes and differences between the epaxial and hypaxial lineage. Dev Dyn. 2004 Oct;231(2):402-15
1J:96910 Blaess S, Graus-Porta D, Belvindrah R, Radakovits R, Pons S, Littlewood-Evans A, Senften M, Guo H, Li Y, Miner JH, Reichardt LF, Muller U, Beta1-integrins are critical for cerebellar granule cell precursor proliferation. J Neurosci. 2004 Mar 31;24(13):3402-12
7J:49179 Brancaccio M, Cabodi S, Belkin AM, Collo G, Koteliansky VE, Tomatis D, Altruda F, Silengo L, Tarone G, Differential onset of expression of alpha 7 and beta 1D integrins during mouse heart and skeletal muscle development. Cell Adhes Commun. 1998 Mar;5(3):193-205
2*J:97068 Cachaco AS, Pereira CS, Pardal RG, Bajanca F, Thorsteinsdottir S, Integrin repertoire on myogenic cells changes during the course of primary myogenesis in the mouse. Dev Dyn. 2005 Apr;232(4):1069-78
2J:195350 Chaen T, Konno T, Egashira M, Bai R, Nomura N, Nomura S, Hirota Y, Sakurai T, Imakawa K, Estrogen-dependent uterine secretion of osteopontin activates blastocyst adhesion competence. PLoS One. 2012;7(11):e48933
1J:84858 Chan CS, Weeber EJ, Kurup S, Sweatt JD, Davis RL, Integrin requirement for hippocampal synaptic plasticity and spatial memory. J Neurosci. 2003 Aug 6;23(18):7107-16
2J:153959 Conti FJ, Monkley SJ, Wood MR, Critchley DR, Muller U, Talin 1 and 2 are required for myoblast fusion, sarcomere assembly and the maintenance of myotendinous junctions. Development. 2009 Nov;136(21):3597-606
1*J:190037 Debrand E, Conti FJ, Bate N, Spence L, Mazzeo D, Pritchard CA, Monkley SJ, Critchley DR, Mice carrying a complete deletion of the talin2 coding sequence are viable and fertile. Biochem Biophys Res Commun. 2012 Sep 21;426(2):190-5
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
9J:100236 Flintoff-Dye NL, Welser J, Rooney J, Scowen P, Tamowski S, Hatton W, Burkin DJ, Role for the alpha7beta1 integrin in vascular development and integrity. Dev Dyn. 2005 Sep;234(1):11-21
3*J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
2J:50235 Gimond C, Baudoin C, van der Neut R, Kramer D, Calafat J, Sonnenberg A, Cre-loxP-mediated inactivation of the alpha6A integrin splice variant in vivo: evidence for a specific functional role of alpha6A in lymphocyte migration but not in heart development. J Cell Biol. 1998 Oct 5;143(1):253-66
1*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1*J:142018 Hager M, Bigotti MG, Meszaros R, Carmignac V, Holmberg J, Allamand V, Akerlund M, Kalamajski S, Brancaccio A, Mayer U, Durbeej M, Cib2 binds integrin alpha7Bbeta1D and is reduced in laminin alpha2 chain-deficient muscular dystrophy. J Biol Chem. 2008 Sep 5;283(36):24760-9
5*J:32724 Hierck BP, Poelmann RE, van Iperen L, Brouwer A, Gittenberger-de Groot AC, Differential expression of alpha-6 and other subunits of laminin binding integrins during development of the murine heart. Dev Dyn. 1996 May;206(1):100-11
1*J:118937 Kaji K, Nichols J, Hendrich B, Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells. Development. 2007 Mar;134(6):1123-32
3*J:142671 Kalsotra A, Xiao X, Ward AJ, Castle JC, Johnson JM, Burge CB, Cooper TA, A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart. Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20333-8
11J:72381 Klaffky E, Williams R, Yao CC, Ziober B, Kramer R, Sutherland A, Trophoblast-Specific Expression and Function of the Integrin alpha7 Subunit in the Peri-implantation Mouse Embryo. Dev Biol. 2001 Nov 1;239(1):161-75
3J:129899 Lathia JD, Patton B, Eckley DM, Magnus T, Mughal MR, Sasaki T, Caldwell MA, Rao MS, Mattson MP, ffrench-Constant C, Patterns of laminins and integrins in the embryonic ventricular zone of the CNS. J Comp Neurol. 2007 Dec 20;505(6):630-43
1J:242127 Liu Z, Li W, Ma X, Ding N, Spallotta F, Southon E, Tessarollo L, Gaetano C, Mukouyama YS, Thiele CJ, Essential role of the zinc finger transcription factor Casz1 for mammalian cardiac morphogenesis and development. J Biol Chem. 2014 Oct 24;289(43):29801-16
1J:217881 Mlih M, Host L, Martin S, Niederhoffer N, Monassier L, Terrand J, Messaddeq N, Radke M, Gotthardt M, Bruban V, Kober F, Bernard M, Canet-Soulas E, Abt-Jijon F, Boucher P, Matz RL, The Src Homology and Collagen A (ShcA) Adaptor Protein Is Required for the Spatial Organization of the Costamere/Z-disk Network during Heart Development. J Biol Chem. 2015 Jan 23;290(4):2419-30
1J:202072 Negron-Perez VM, Echevarria FD, Huffman SR, Rivera RM, Determination of allelic expression of h19 in pre- and peri-implantation mouse embryos. Biol Reprod. 2013 Apr;88(4):97
1*J:130047 Nishioka N, Yamamoto S, Kiyonari H, Sato H, Sawada A, Ota M, Nakao K, Sasaki H, Tead4 is required for specification of trophectoderm in pre-implantation mouse embryos. Mech Dev. 2008 Mar-Apr;125(3-4):270-83
2J:178574 Nitzki F, Zibat A, Frommhold A, Schneider A, Schulz-Schaeffer W, Braun T, Hahn H, Uncommitted precursor cells might contribute to increased incidence of embryonal rhabdomyosarcoma in heterozygous Patched1-mutant mice. Oncogene. 2011 Oct 27;30(43):4428-36
1J:242767 Nunes AM, Wuebbles RD, Sarathy A, Fontelonga TM, Deries M, Burkin DJ, Thorsteinsdottir S, Impaired fetal muscle development and JAK-STAT activation mark disease onset and progression in a mouse model for merosin-deficient congenital muscular dystrophy. Hum Mol Genet. 2017 Jun 01;26(11):2018-2033
2J:83980 Previtali SC, Dina G, Nodari A, Fasolini M, Wrabetz L, Mayer U, Feltri ML, Quattrini A, Schwann cells synthesize alpha7beta1 integrin which is dispensable for peripheral nerve development and myelination. Mol Cell Neurosci. 2003 Jun;23(2):210-8
2J:84372 Previtali SC, Nodari A, Taveggia C, Pardini C, Dina G, Villa A, Wrabetz L, Quattrini A, Feltri ML, Expression of laminin receptors in schwann cell differentiation: evidence for distinct roles. J Neurosci. 2003 Jul 2;23(13):5520-30
1J:253620 Pryce BR, Al-Zahrani KN, Dufresne S, Belkina N, Labreche C, Patino-Lopez G, Frenette J, Shaw S, Sabourin LA, Deletion of the Ste20-like kinase SLK in skeletal muscle results in a progressive myopathy and muscle weakness. Skelet Muscle. 2017 Feb 2;7(1):3
1J:76364 Pun S, Sigrist M, Santos AF, Ruegg MA, Sanes JR, Jessell TM, Arber S, Caroni P, An intrinsic distinction in neuromuscular junction assembly and maintenance in different skeletal muscles. Neuron. 2002 Apr 25;34(3):357-70
1J:203162 Ray A, Treloar HB, IgSF8: a developmentally and functionally regulated cell adhesion molecule in olfactory sensory neuron axons and synapses. Mol Cell Neurosci. 2012 Jul;50(3-4):238-49
1J:85864 Rossant J, Chazaud C, Yamanaka Y, Lineage allocation and asymmetries in the early mouse embryo. Philos Trans R Soc Lond B Biol Sci. 2003 Aug 29;358(1436):1341-8; discussion 1349
1J:146417 Schwander M, Shirasaki R, Pfaff SL, Muller U, Beta1 integrins in muscle, but not in motor neurons, are required for skeletal muscle innervation. J Neurosci. 2004 Sep 15;24(37):8181-91
2*J:32804 Shim C, Kwon HB, Kim K, Differential expression of laminin chain-specific mRNA transcripts during mouse preimplantation embryo development. Mol Reprod Dev. 1996 May;44(1):44-55
1J:69804 Sixt M, Engelhardt B, Pausch F, Hallmann R, Wendler O, Sorokin LM, Endothelial cell laminin isoforms, laminins 8 and 10, play decisive roles in T cell recruitment across the blood-brain barrier in experimental autoimmune encephalomyelitis. J Cell Biol. 2001 May 28;153(5):933-46
2*J:98502 Strumpf D, Mao CA, Yamanaka Y, Ralston A, Chawengsaksophak K, Beck F, Rossant J, Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocyst. Development. 2005 May;132(9):2093-102
1*J:16243 Sutherland AE, Calarco PG, Damsky CH, Developmental regulation of integrin expression at the time of implantation in the mouse embryo. Development. 1993 Dec;119(4):1175-86
1J:44406 van der Flier A, Gaspar AC, Thorsteinsdottir S, Baudoin C, Groeneveld E, Mummery CL, Sonnenberg A, Spatial and temporal expression of the beta1D integrin during mouse development. Dev Dyn. 1997 Dec;210(4):472-86
13J:37016 Velling T, Collo G, Sorokin L, Durbeej M, Zhang H, Gullberg D, Distinct alpha 7A beta 1 and alpha 7B beta 1 integrin expression patterns during mouse development: alpha 7A is restricted to skeletal muscle but alpha 7B is expressed in striated muscle, vasculature, and nervous system. Dev Dyn. 1996 Dec;207(4):355-71
8J:141490 Welser JV, Lange ND, Flintoff-Dye N, Burkin HR, Burkin DJ, Placental defects in alpha7 integrin null mice. Placenta. 2007 Nov-Dec;28(11-12):1219-28

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last database update
02/05/2019
MGI 6.13
The Jackson Laboratory