Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits long-chain fatty acid binding activity; oxidative phosphorylation uncoupler activity; and purine ribonucleotide binding activity. Involved in several processes, including brown fat cell differentiation; diet induced thermogenesis; and positive regulation of cold-induced thermogenesis. Localizes to mitochondrial inner membrane. Is expressed in adipose tissue; bone; submandibular gland; testis; and thymus. Human ortholog(s) of this gene implicated in hypertension and type 2 diabetes mellitus. Orthologous to human UCP1 (uncoupling protein 1).