Automated description from the Alliance of Genome Resources
Predicted to have several functions, including Hsp70 protein binding activity; chaperone binding activity; and protein homodimerization activity. Involved in several processes, including cellular response to leukemia inhibitory factor; positive regulation of bone resorption; and positive regulation of lymphocyte proliferation. Localizes to several cellular components, including the HFE-transferrin receptor complex; endosome; and extracellular exosome. Human ortholog(s) of this gene implicated in breast carcinoma; multiple myeloma; ovarian cancer; and primary immunodeficiency disease. Orthologous to human TFRC (transferrin receptor).