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Gene Ontology Classifications
Symbol
Name
ID
Slc6a6
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
MGI:98488

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GO curators for mouse genes have assigned the following annotations to the gene product of Slc6a6. (This text reflects annotations as of Thursday, July 24, 2014.)
Summary from NCBI RefSeq


[Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a multi-pass membrane protein that is a member of a family of sodium and chloride-ion dependent transporters. The encoded protein transports taurine and beta-alanine. There is a pseudogene for this gene on chromosome 21. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
Summary text based on GO annotations supported by experimental evidence in mouse
Summary text based on GO annotations supported by experimental evidence in other organisms
Summary text based on GO annotations supported by structural data
Summary text for additional MGI annotations
References
  1. Heller-Stilb B et al. (2002) Disruption of the taurine transporter gene (taut) leads to retinal degeneration in mice. FASEB J, 16:231-3. (PubMed:11772953)
  2. Lane PW. (1992) Crimpy (cpy) a new recessive hair mutation on chromosome 15 of the mouse Mouse Genome, 90:682-83.
  3. Liu QR et al. (1992) Cloning and expression of a cDNA encoding the transporter of taurine and beta-alanine in mouse brain. Proc Natl Acad Sci U S A, 89:12145-9. (PubMed:1465453)
  4. Vinnakota S et al. (1997) Molecular characterization and in situ localization of a mouse retinal taurine transporter. J Neurochem, 69:2238-50. (PubMed:9375654)



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Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  ISS Inferred from sequence or structural similarity
  ISO Inferred from sequence orthology
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  NAS Non-traceable author statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/23/2014
MGI 5.20
The Jackson Laboratory