Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription factor binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including enteric nervous system development; neural crest cell migration; and positive regulation of morphogenesis of an epithelium. Acts upstream of or within several processes, including negative regulation of cell differentiation; nervous system development; and regulation of gene expression. Located in cytoplasm and nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Orthologous to human SOX8 (SRY-box transcription factor 8).