Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including lacrimal gland development; nervous system development; and neural crest cell migration. Localizes to extrinsic component of mitochondrial outer membrane and nucleus. Predicted to colocalize with chromatin. Is expressed in several structures, including alimentary system; genitourinary system; mesenchyme derived from neural crest; nervous system; and neurogenic placode. Used to study Kallmann syndrome; PCWH syndrome; and Waardenburg syndrome type 4C. Human ortholog(s) of this gene implicated in Kallmann syndrome; PCWH syndrome; Waardenburg syndrome type 2E; and Waardenburg syndrome type 4C. Orthologous to human SOX10 (SRY-box transcription factor 10).