Automated description from the Alliance of Genome Resources
Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in central nervous system development and regulation of transcription by RNA polymerase II. Predicted to localize to the nucleoplasm. Used to study Scheuermann's disease. Human ortholog(s) of this gene implicated in Marshall-Smith syndrome and Sotos syndrome. Orthologous to human NFIX (nuclear factor I X).