Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in central nervous system development and regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Used to study Scheuermann's disease. Human ortholog(s) of this gene implicated in Marshall-Smith syndrome and Sotos syndrome. Orthologous to human NFIX (nuclear factor I X).