Automated description from the Alliance of Genome Resources (Release 3.1.1)
Predicted to have metalloendopeptidase activity. Involved in several processes, including cellular response to amino acid stimulus; negative regulation of protein kinase B signaling; and positive regulation of oxidative stress-induced cell death. Localizes to cytosol and mitochondrion. Is expressed in several structures, including axial skeleton thoracic region; genitourinary system; jaw; lung; and oral epithelium. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); end stage renal disease; esophagus adenocarcinoma; osteoarthritis; and von Hippel-Lindau disease. Orthologous to human MMP3 (matrix metallopeptidase 3).