Automated description from the Alliance of Genome Resources (Release 5.1.1)
Enables ganglioside GT1b binding activity; protein homodimerization activity; and sialic acid binding activity. Involved in several processes, including central nervous system myelin formation; negative regulation of neuron apoptotic process; and positive regulation of myelination. Acts upstream of or within axon regeneration and transmission of nerve impulse. Located in Schmidt-Lanterman incisure; myelin sheath adaxonal region; and paranode region of axon. Is integral component of plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system gland; liver and biliary system; and nervous system. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 75. Orthologous to human MAG (myelin associated glycoprotein).