Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable structural molecule activity. Involved in several processes, including hair follicle morphogenesis; positive regulation of hair follicle development; and positive regulation of translation. Acts upstream of or within intermediate filament organization; keratinization; and morphogenesis of an epithelium. Located in cell periphery and cytoplasm. Is active in cornified envelope. Is expressed in several structures, including alimentary system; exocrine system; eyelid epithelium; immune system; and skin. Used to study pachyonychia congenita. Human ortholog(s) of this gene implicated in ectodermal dysplasia; pachyonychia congenita; and steatocystoma multiplex. Orthologous to human KRT17 (keratin 17).