Automated description from the Alliance of Genome Resources
Exhibits integrin binding activity. Contributes to laminin binding activity. Involved in several processes, including cell migration involved in sprouting angiogenesis; cell morphogenesis involved in differentiation; and striated muscle cell differentiation. Localizes to several cellular components, including the Schaffer collateral - CA1 synapse; integral component of plasma membrane; and myelin sheath abaxonal region. Colocalizes with the cytoplasmic vesicle and perinuclear region of cytoplasm. Used to study Hirschsprung's disease. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and limb. Orthologous to human ITGB1 (integrin subunit beta 1).