Automated description from the Alliance of Genome Resources
Contributes to interleukin-11 binding activity and interleukin-11 receptor activity. Involved in several processes, including glycogen metabolic process; positive regulation of astrocyte differentiation; and regulation of Notch signaling pathway. Localizes to the dendrite; external side of plasma membrane; and neuronal cell body. Used to study rheumatoid arthritis and stomach cancer. Human ortholog(s) of this gene implicated in arteriosclerosis and hyperandrogenism. Is expressed in several structures, including bone marrow; early conceptus; female reproductive system; gonad; and nervous system. Orthologous to human IL6ST (interleukin 6 signal transducer).