Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables identical protein binding activity and ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential. Acts upstream of or within monoatomic ion transmembrane transport and regulation of presynaptic membrane potential. Part of serotonin-activated cation-selective channel complex. Is expressed in several structures, including central nervous system; eye; gallbladder; genitourinary system; and gut. Human ortholog(s) of this gene implicated in irritable bowel syndrome. Orthologous to human HTR3A (5-hydroxytryptamine receptor 3A).