Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables G protein-coupled serotonin receptor activity. Involved in several processes, including behavioral fear response; serotonin metabolic process; and serotonin receptor signaling pathway. Acts upstream of or within G protein-coupled serotonin receptor signaling pathway and gamma-aminobutyric acid signaling pathway. Predicted to be located in axon hillock and plasma membrane. Predicted to be active in GABA-ergic synapse; dendrite; and presynaptic membrane. Is expressed in several structures, including central nervous system; exocrine gland; eye; genitourinary system; and intestine. Used to study anxiety disorder. Human ortholog(s) of this gene implicated in alcohol dependence; anxiety disorder; depressive disorder; panic disorder; and withdrawal disorder. Orthologous to human HTR1A (5-hydroxytryptamine receptor 1A).