Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits several functions, including calmodulin binding activity; cation binding activity; and ion channel activity. Involved in several processes, including chemical synaptic transmission; learning or memory; and nervous system development. Localizes to several cellular components, including glutamatergic synapse; integral component of plasma membrane; and synaptic vesicle membrane. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; sensory organ; and skeleton. Used to study autism spectrum disorder and schizophrenia. Human ortholog(s) of this gene implicated in alcohol use disorder; autosomal dominant non-syndromic intellectual disability 8; and cerebral infarction. Orthologous to human GRIN1 (glutamate ionotropic receptor NMDA type subunit 1).