Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits kainate selective glutamate receptor activity and transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Involved in excitatory postsynaptic potential; glutamatergic synaptic transmission; and regulation of synaptic vesicle fusion to presynaptic active zone membrane. Localizes to endoplasmic reticulum; hippocampal mossy fiber to CA3 synapse; and integral component of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; immune system; and visual system. Orthologous to human GRIK5 (glutamate ionotropic receptor kainate type subunit 5).