Automated description from the Alliance of Genome Resources
Exhibits several functions, including phosphatidylinositol 3-kinase binding activity; protein tyrosine kinase activity; and ubiquitin protein ligase binding activity. Involved in several processes, including hematopoietic or lymphoid organ development; negative regulation of cytokine production; and positive regulation of cytokine secretion. Localizes to the external side of plasma membrane. Used to study acute myeloid leukemia and juvenile myelomonocytic leukemia. Human ortholog(s) of this gene implicated in acute myeloid leukemia; precursor lymphoblastic lymphoma/leukemia; and prostate cancer. Orthologous to human FLT3 (fms related tyrosine kinase 3).