Automated description from the Alliance of Genome Resources
Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including blood circulation; megakaryocyte development; and positive regulation of transcription by RNA polymerase II. Localizes to the nucleus. Used to study systemic scleroderma. Human ortholog(s) of this gene implicated in blood platelet disease and thrombocytopenia. Is expressed in several structures, including alimentary system; branchial arch; cardiovascular system; genitourinary system; and nervous system. Orthologous to human FLI1 (Fli-1 proto-oncogene, ETS transcription factor).