Automated description from the Alliance of Genome Resources
Exhibits extracellular matrix binding activity. Involved in several processes, including extracellular matrix organization; skeletal muscle tissue development; and stress fiber assembly. Localizes to the elastic fiber. Used to study aortic valve disease; essential hypertension; and supravalvular aortic stenosis. Human ortholog(s) of this gene implicated in several diseases, including aortic aneurysm (multiple); aortic valve stenosis (multiple); cutis laxa (multiple); rheumatic disease (multiple); and vasculitis (multiple). Orthologous to human ELN (elastin).