Automated description from the Alliance of Genome Resources (Release 4.1.0)
Enables extracellular matrix binding activity. Acts upstream of or within several processes, including regulation of actin filament polymerization; skeletal muscle tissue development; and stress fiber assembly. Located in elastic fiber. Is expressed in several structures, including alimentary system; cardiovascular system; cranium; limb; and respiratory system. Used to study aortic valve disease; essential hypertension; and supravalvular aortic stenosis. Human ortholog(s) of this gene implicated in several diseases, including Williams-Beuren syndrome; aortic disease (multiple); autoimmune disease (multiple); cutis laxa (multiple); and retinal disease (multiple). Orthologous to human ELN (elastin).