Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits extracellular matrix binding activity. Involved in several processes, including regulation of actin filament polymerization; skeletal muscle tissue development; and stress fiber assembly. Localizes to elastic fiber. Is expressed in several structures, including alimentary system; cardiovascular system; cranium; limb; and respiratory system. Used to study aortic valve disease; essential hypertension; and supravalvular aortic stenosis. Human ortholog(s) of this gene implicated in several diseases, including aortic disease (multiple); autoimmune disease of musculoskeletal system (multiple); cutis laxa (multiple); retinal disease (multiple); and vasculitis (multiple). Orthologous to human ELN (elastin).