Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables peptidase activity. Acts upstream of or within zymogen activation. Predicted to be located in several cellular components, including acrosomal vesicle; apical part of cell; and extracellular space. Predicted to be part of protein-containing complex. Predicted to be active in secretory granule. Human ortholog(s) of this gene implicated in cardiomyopathy; chronic kidney disease; end stage renal disease; hypertension; and myocardial infarction. Orthologous to several human genes including KLK1 (kallikrein 1).