Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits several functions, including DNA (cytosine-5-)-methyltransferase activity; nucleic acid binding activity; and zinc ion binding activity. Involved in several processes, including DNA metabolic process; cellular response to amino acid stimulus; and negative regulation of gene expression. Localizes to nucleus; pericentric heterochromatin; and replication fork. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in Graves' disease; autosomal dominant cerebellar ataxia, deafness and narcolepsy; hereditary sensory neuropathy; and hereditary sensory neuropathy type 1E. Orthologous to human DNMT1 (DNA methyltransferase 1).