Automated description from the Alliance of Genome Resources (Release 3.2)
Predicted to have identical protein binding activity; protease binding activity; and serine-type endopeptidase inhibitor activity. Involved in response to cytokine and response to peptide hormone. Localizes to extracellular region. Is expressed in gut and liver lobe. Human ortholog(s) of this gene implicated in several diseases, including alpha 1-antitrypsin deficiency; artery disease (multiple); chronic obstructive pulmonary disease (multiple); inflammatory bowel disease (multiple); and liver disease (multiple). Orthologous to human SERPINA1 (serpin family A member 1).