Automated description from the Alliance of Genome Resources
Exhibits steroid 11-beta-monooxygenase activity. Involved in several processes, including aldosterone biosynthetic process; drinking behavior; and regulation of systemic arterial blood pressure by hormone. Localizes to the mitochondrion. Human ortholog(s) of this gene implicated in congenital adrenal hyperplasia; diabetes mellitus (multiple); dilated cardiomyopathy 1H; hypertension (multiple); and primary hyperaldosteronism (multiple). Is expressed in adrenal gland and gland. Orthologous to several human genes including CYP11B2 (cytochrome P450 family 11 subfamily B member 2).