Automated description from the Alliance of Genome Resources (Release 4.1.0)
Predicted to be involved in several processes, including antigen receptor-mediated signaling pathway; negative regulation of lymphocyte activation; and positive regulation of apoptotic process. Predicted to act upstream of or within adaptive immune response. Located in external side of plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); hematologic cancer (multiple); hepatitis B; kidney disease (multiple); and primary immunodeficiency disease (multiple). Orthologous to human CTLA4 (cytotoxic T-lymphocyte associated protein 4).